Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   SAA6159_RS09675 Genome accession   NC_017338
Coordinates   1984726..1985355 (-) Length   209 a.a.
NCBI ID   WP_000153535.1    Uniprot ID   Q7A2Q1
Organism   Staphylococcus aureus subsp. aureus JKD6159     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1979726..1990355
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SAA6159_RS09645 (SAA6159_01809) - 1980145..1980675 (-) 531 WP_000184381.1 acyl-CoA thioesterase -
  SAA6159_RS09650 (SAA6159_01810) - 1980765..1982021 (-) 1257 WP_078055786.1 aminopeptidase -
  SAA6159_RS09655 (SAA6159_01811) - 1982024..1982224 (-) 201 WP_000180460.1 DUF1128 family protein -
  SAA6159_RS09660 (SAA6159_01812) - 1982371..1982835 (+) 465 WP_000228666.1 low molecular weight protein-tyrosine-phosphatase -
  SAA6159_RS09665 (SAA6159_01813) - 1982842..1983117 (+) 276 WP_000428173.1 YtxH domain-containing protein -
  SAA6159_RS09670 (SAA6159_01814) - 1983395..1984612 (+) 1218 WP_045158466.1 YihY/virulence factor BrkB family protein -
  SAA6159_RS09675 (SAA6159_01815) vraR 1984726..1985355 (-) 630 WP_000153535.1 two-component system response regulator VraR Regulator
  SAA6159_RS09680 (SAA6159_01816) vraS 1985345..1986388 (-) 1044 WP_001017131.1 sensor histidine kinase Regulator
  SAA6159_RS09685 (SAA6159_01817) liaF 1986385..1987086 (-) 702 WP_000149064.1 cell wall-active antibiotics response protein LiaF -
  SAA6159_RS09690 (SAA6159_01818) - 1987101..1987487 (-) 387 WP_001110179.1 hypothetical protein -
  SAA6159_RS09695 (SAA6159_01819) map 1987704..1988462 (-) 759 WP_000636142.1 type I methionyl aminopeptidase -
  SAA6159_RS09700 (SAA6159_01820) - 1988990..1989976 (+) 987 WP_000999713.1 aromatic acid exporter family protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23559.32 Da        Isoelectric Point: 5.3935

>NTDB_id=36864 SAA6159_RS09675 WP_000153535.1 1984726..1985355(-) (vraR) [Staphylococcus aureus subsp. aureus JKD6159]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMEDMDGVEATTQIKKDLPQIKVL
MLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=36864 SAA6159_RS09675 WP_000153535.1 1984726..1985355(-) (vraR) [Staphylococcus aureus subsp. aureus JKD6159]
ATGACGATTAAAGTATTGTTTGTGGATGATCATGAAATGGTACGTATAGGAATTTCAAGTTATCTATCAACGCAAAGTGA
TATTGAAGTAGTTGGTGAAGGCGCTTCTGGTAAAGAAGCAATTGCCAAAGCCCATGAGTTGAAGCCAGATTTAATTTTAA
TGGATTTACTTATGGAAGACATGGATGGTGTAGAAGCGACGACTCAGATTAAAAAAGATTTACCGCAAATTAAAGTATTA
ATGTTAACTAGTTTTATTGAAGATAAAGAGGTATATCGTGCATTAGATGCAGGTGTCGATAGTTACATTTTAAAAACAAC
AAGTGCAAAAGATATCGCAGATGCAGTTCGTAAAACTTCTAGAGGAGAATCTGTTTTTGAACCGGAAGTTTTAGTGAAAA
TGCGTAATCGTATGAAAAAGCGCGCAGAGTTATATGAAATGCTTACAGAACGAGAAATGGAAATATTATTATTGATTGCG
AAAGGTTACTCAAATCAAGAAATTGCTAGTGCATCGCATATTACTATTAAAACGGTTAAGACACATGTGAGTAACATTTT
AAGTAAGTTAGAAGTGCAAGATAGAACACAAGCTGTTATCTATGCATTCCAACATAATTTAATTCAATAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 2RNJ
  PDB 4GVP
  PDB 4IF4
  PDB 7VE6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

100

100

1
  degU Bacillus subtilis subsp. subtilis str. 168

34.821

100

0.373

Multiple sequence alignment