Detailed information NTG0368517

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: SSPS47_RS19530
• Genome accession: NZ_CP048397
• Coordinates: 4369981..4371114 (-)
• Length: 377 a.a.
• NCBI ID: WP_078075735.1
• Uniprot ID: A0A1U9QSN1
• Organism: Streptomyces sp. S4.7
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 4364981..4376114

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSPS47_RS19505 (SSPS47_19750)	-	4365259..4366125 (-)	867	WP_164252181.1	hypothetical protein	-
SSPS47_RS19510 (SSPS47_19755)	-	4366113..4366733 (-)	621	WP_164252182.1	SigE family RNA polymerase sigma factor	-
SSPS47_RS19515 (SSPS47_19760)	-	4367037..4367948 (-)	912	WP_164252183.1	A/G-specific adenine glycosylase	-
SSPS47_RS19520 (SSPS47_19765)	-	4368102..4368866 (-)	765	WP_164252184.1	phosphatase PAP2 family protein	-
SSPS47_RS19525 (SSPS47_19770)	-	4369048..4369890 (+)	843	WP_164252185.1	hypothetical protein	-
SSPS47_RS19530 (SSPS47_19775)	disA	4369981..4371114 (-)	1134	WP_078075735.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
SSPS47_RS19535 (SSPS47_19780)	radA/sms	4371159..4372571 (-)	1413	WP_164252186.1	DNA repair protein RadA	Machinery gene
SSPS47_RS19540 (SSPS47_19785)	-	4372678..4374546 (+)	1869	WP_239064984.1	hypothetical protein	-
SSPS47_RS19545 (SSPS47_19790)	-	4374572..4375390 (-)	819	WP_147878339.1	hypothetical protein	-

Sequence

Protein

• Length: 377 a.a.
• Molecular weight: 40512.47 Da
• Isoelectric Point: 4.9406

>NTDB_id=368517 SSPS47_RS19530 WP_078075735.1 4369981..4371114(-) (disA) [Streptomyces sp. S4.7]
MAANDRAAAPGKSGGGSGGSGTEALMRASLSAVAPGMALRDGLERILRGNTGGLIVLGMDKTVETMCTGGFVLDVEFTAT
RLRELCKLDGALILDKDITKILRAGVQLVPDASIPTEETGTRHRTADRVSKQCGFPVISVSQSMRLIALYVDGERRVLEE
SAAILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVSQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDE
LIAGVEPERELVVRDYVPEPTAKRSRTVAEAMTELDALSHTELLELPVVARALGYSGSPETLDSAVSPRGYRLLAKVPRL
PGAIIERLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1134 bp

>NTDB_id=368517 SSPS47_RS19530 WP_078075735.1 4369981..4371114(-) (disA) [Streptomyces sp. S4.7]
GTGGCAGCCAACGACCGGGCAGCAGCACCCGGAAAGTCCGGTGGTGGCTCCGGTGGATCCGGCACCGAAGCGCTGATGCG
CGCCTCACTGAGCGCCGTAGCGCCCGGCATGGCGCTGCGTGACGGGCTGGAGCGGATCCTCCGGGGGAACACCGGCGGTC
TCATCGTCCTGGGCATGGACAAGACCGTCGAGACGATGTGCACGGGCGGCTTCGTGCTGGACGTGGAATTCACCGCCACG
AGGCTCCGCGAGCTCTGCAAGCTCGACGGCGCGCTCATTCTCGACAAAGACATCACCAAAATTCTGCGGGCCGGTGTCCA
GCTCGTGCCCGACGCCTCCATCCCCACCGAGGAGACCGGCACGCGCCACCGCACGGCGGACCGGGTGTCCAAGCAGTGCG
GGTTCCCGGTGATCTCCGTGTCCCAGTCGATGCGGCTGATCGCGCTGTACGTGGACGGGGAGCGCCGGGTCCTGGAGGAG
TCGGCGGCGATCCTGTCGCGCGCCAACCAGGCGCTGGCGACCCTGGAGCGGTACAAGCTCCGGCTGGACGAGGTCGCGGG
CACGCTCTCCGCGCTGGAGATCGAGGACCTGGTGACGGTCCGGGACGTGACGGCGGTGTCGCAGCGCCTGGAGATGGTGC
GCAGGATCGCCACGGAGATCGCCGAGTACGTGGTCGAGTTGGGCACCGACGGGCGGCTTCTCTCCCTCCAGCTCGACGAG
TTGATCGCGGGCGTCGAGCCCGAGCGTGAGCTCGTCGTACGGGACTACGTGCCCGAGCCGACGGCGAAGCGGTCGCGCAC
GGTCGCCGAGGCGATGACCGAGCTTGACGCGCTCTCCCACACGGAGCTGCTGGAACTGCCCGTCGTGGCCCGTGCGTTGG
GCTACAGCGGTTCGCCCGAGACACTGGACTCGGCGGTCTCACCGCGCGGCTACCGGCTGCTGGCCAAGGTGCCGCGTCTG
CCGGGCGCCATCATCGAGCGGCTGGTCGAGCACTTCGGCGGTCTCCAGAAGCTGCTGGCGGCGAGCGTCGACGATCTCCA
GACGGTGGACGGCGTGGGCGAGGCGCGGGCGCGCAGCGTGCGCGAGGGGCTGTCGCGGCTTGCGGAGTCGTCGATTTTGG
AGCGGTACGTCTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller linker region (DisA-linker) (158-300)

• Helix-hairpin-helix motif (HHH_2) (327-362)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (41-154)

3D structure

• AlphaFold DB: A0A1U9QSN1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.938	94.695	0.435