Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   GZS09_RS09285 Genome accession   NZ_CP048359
Coordinates   1959889..1960545 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain 53     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1954889..1965545
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GZS09_RS09255 (GZS09_09255) dcyD 1955769..1956755 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  GZS09_RS09260 (GZS09_09260) tcyL 1956770..1957438 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  GZS09_RS09265 (GZS09_09265) tcyN 1957435..1958187 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  GZS09_RS09270 (GZS09_09270) sdiA 1958417..1959139 (+) 723 WP_001474368.1 transcriptional regulator SdiA -
  GZS09_RS09275 (GZS09_09275) yecF 1959206..1959430 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  GZS09_RS09280 (GZS09_09280) yecU 1959417..1959593 (-) 177 WP_001307856.1 protein YecU -
  GZS09_RS26295 - 1959676..1959747 (-) 72 Protein_1834 transcriptional regulator -
  GZS09_RS09285 (GZS09_09285) letA 1959889..1960545 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  GZS09_RS09290 (GZS09_09290) uvrC 1960542..1962374 (+) 1833 WP_001283426.1 excinuclease ABC subunit UvrC Machinery gene
  GZS09_RS09295 (GZS09_09295) pgsA 1962431..1962979 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  GZS09_RS09315 (GZS09_09315) yecA 1963628..1964293 (+) 666 Protein_1838 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=368191 GZS09_RS09285 WP_000611328.1 1959889..1960545(+) (letA) [Escherichia coli strain 53]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=368191 GZS09_RS09285 WP_000611328.1 1959889..1960545(+) (letA) [Escherichia coli strain 53]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482