Detailed information NTG0367995

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: FHQ17_RS04360
• Genome accession: NZ_CP040883
• Coordinates: 936907..937953 (+)
• Length: 348 a.a.
• NCBI ID: WP_001830374.1
• Uniprot ID: A0A0N1EGU4
• Organism: Staphylococcus epidermidis strain O47
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 931907..942953

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FHQ17_RS04335 (FHQ17_04525)	-	933048..933584 (+)	537	WP_002470337.1	hypothetical protein	-
FHQ17_RS04340 (FHQ17_04530)	-	933735..934721 (-)	987	WP_001830388.1	aromatic acid exporter family protein	-
FHQ17_RS04345 (FHQ17_04535)	map	934895..935650 (+)	756	WP_002457092.1	type I methionyl aminopeptidase	-
FHQ17_RS04350 (FHQ17_04540)	-	935808..936194 (+)	387	WP_001830382.1	hypothetical protein	-
FHQ17_RS04355 (FHQ17_04545)	liaF	936209..936910 (+)	702	WP_001830436.1	cell wall-active antibiotics response protein LiaF	-
FHQ17_RS04360 (FHQ17_04550)	vraS	936907..937953 (+)	1047	WP_001830374.1	sensor histidine kinase	Regulator
FHQ17_RS04365 (FHQ17_04555)	vraR	937943..938572 (+)	630	WP_001830439.1	two-component system response regulator VraR	Regulator
FHQ17_RS04370 (FHQ17_04560)	-	938629..939807 (-)	1179	WP_001830411.1	YihY/virulence factor BrkB family protein	-
FHQ17_RS04375 (FHQ17_04565)	-	940214..940498 (-)	285	WP_001830401.1	YtxH domain-containing protein	-
FHQ17_RS04380 (FHQ17_04570)	-	940506..940970 (-)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
FHQ17_RS04385 (FHQ17_04575)	-	941111..941326 (+)	216	WP_001830421.1	DUF1128 domain-containing protein	-
FHQ17_RS04390 (FHQ17_04580)	-	941328..942569 (+)	1242	WP_001832467.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40066.49 Da
• Isoelectric Point: 5.8512

>NTDB_id=367995 FHQ17_RS04360 WP_001830374.1 936907..937953(+) (vraS) [Staphylococcus epidermidis strain O47]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVLLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=367995 FHQ17_RS04360 WP_001830374.1 936907..937953(+) (vraS) [Staphylococcus epidermidis strain O47]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAGGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTCTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCA
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAAAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCCAGGGAATTACATGATTCTGTTAGT
CAACAATTATTTGCTGCGAGCATGATGCTATCGGCGATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTATTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTTTAGGTGAAGGAATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTGTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGCATTGAAGATCACTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACAAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GGTTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0N1EGU4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	93.023	98.851	0.92