Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   GZS16_RS09485 Genome accession   NZ_CP048310
Coordinates   2013497..2014153 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain 32-4     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2008497..2019153
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GZS16_RS09455 (GZS16_09455) dcyD 2009377..2010363 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  GZS16_RS09460 (GZS16_09460) tcyL 2010378..2011046 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  GZS16_RS09465 (GZS16_09465) tcyN 2011043..2011795 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  GZS16_RS09470 (GZS16_09470) sdiA 2012025..2012747 (+) 723 WP_001154276.1 transcriptional regulator SdiA -
  GZS16_RS09475 (GZS16_09475) yecF 2012814..2013038 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  GZS16_RS09480 (GZS16_09480) yecU 2013025..2013201 (-) 177 WP_000590347.1 protein YecU -
  GZS16_RS26015 - 2013284..2013355 (-) 72 Protein_1876 transcriptional regulator -
  GZS16_RS09485 (GZS16_09485) letA 2013497..2014153 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  GZS16_RS09490 (GZS16_09490) uvrC 2014150..2015982 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  GZS16_RS09495 (GZS16_09495) pgsA 2016039..2016587 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  GZS16_RS09515 (GZS16_09515) - 2017283..2018023 (-) 741 WP_047149284.1 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=367705 GZS16_RS09485 WP_000611335.1 2013497..2014153(+) (letA) [Escherichia coli strain 32-4]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=367705 GZS16_RS09485 WP_000611335.1 2013497..2014153(+) (letA) [Escherichia coli strain 32-4]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486