Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   FDP16_RS01390 Genome accession   NZ_CP040798
Coordinates   262923..265055 (+) Length   710 a.a.
NCBI ID   WP_176798302.1    Uniprot ID   A0A7H8UY64
Organism   Streptococcus sanguinis strain CGMH058     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 261700..276548 262923..265055 within 0


Gene organization within MGE regions


Location: 261700..276548
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FDP16_RS01385 (FDP16_01440) - 261700..262464 (+) 765 WP_176798301.1 amino acid ABC transporter ATP-binding protein -
  FDP16_RS01390 (FDP16_01445) clpC 262923..265055 (+) 2133 WP_176798302.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  FDP16_RS01395 (FDP16_01450) hsdR 265851..268184 (+) 2334 WP_176798303.1 EcoAI/FtnUII family type I restriction enzme subunit R -
  FDP16_RS01400 (FDP16_01455) - 268197..269660 (+) 1464 WP_176798304.1 class I SAM-dependent DNA methyltransferase -
  FDP16_RS12025 - 269660..270520 (+) 861 WP_371277763.1 restriction endonuclease subunit S -
  FDP16_RS12030 (FDP16_01470) - 270501..271181 (+) 681 WP_371277765.1 restriction endonuclease subunit S -
  FDP16_RS01415 (FDP16_01475) - 271135..271689 (-) 555 WP_176799755.1 restriction endonuclease subunit S -
  FDP16_RS01420 (FDP16_01480) psrA 271723..271986 (-) 264 Protein_261 tyrosine-type DNA invertase PsrA -
  FDP16_RS01425 (FDP16_01485) - 272084..273019 (+) 936 WP_176798305.1 IS30 family transposase -
  FDP16_RS01430 (FDP16_01490) - 272977..273582 (-) 606 WP_371277767.1 tyrosine-type recombinase/integrase -
  FDP16_RS01435 (FDP16_01495) - 273639..275015 (-) 1377 Protein_264 restriction endonuclease subunit S -
  FDP16_RS12035 (FDP16_01505) - 275300..275443 (-) 144 Protein_265 cell envelope -
  FDP16_RS01450 (FDP16_01510) - 275577..276548 (+) 972 WP_176799757.1 serine hydrolase -

Sequence

Protein


Download         Length: 710 a.a.        Molecular weight: 78380.25 Da        Isoelectric Point: 4.8018

>NTDB_id=367197 FDP16_RS01390 WP_176798302.1 262923..265055(+) (clpC) [Streptococcus sanguinis strain CGMH058]
MNNNYNNFNNMDDLFNQLMGRMGGYNSEHRRYLINGREVTPEEFAQYRATGKLPGQGEQTSQTAAQGPKQDGILAKLGRN
LTQEARDGKLDPVIGRNKEIQETAEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISVDISGLEA
GTQYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKPALSRGELTVIGATTQDEYRNTILK
NAALARRFNEVKVNAPSAEDTYQILRGIRDLYEKHHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQH
PVTDVHAVEHEIAEQKDKQEAAVEKEDFEAALNAKTRIEELEKKIQNHTEDMKVTATINDVAESVERMTGVPVSQMGASD
IERLKGMNDRLKAKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGTKEAIIRLDMS
EYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVI
IATSNAGFGYEAGLEEDAEKPDLMDRLKAYFRPEFLNRFNAVIEFSHLKKEDLMEIVNLMLIEVNQTLSKKEIDLAVSDA
AKEFLRDAGYDQVMGVRPLRRVIEQQIRDKVTDFHLDNLDAKHLTADLEDGVLVIREKGAAASEEDKQAE

Nucleotide


Download         Length: 2133 bp        

>NTDB_id=367197 FDP16_RS01390 WP_176798302.1 262923..265055(+) (clpC) [Streptococcus sanguinis strain CGMH058]
ATGAACAACAACTACAACAATTTTAACAATATGGACGACCTTTTCAACCAACTCATGGGGCGCATGGGCGGCTACAACAG
CGAACACCGGCGCTACTTGATTAATGGTAGAGAGGTCACACCGGAAGAGTTTGCTCAGTACCGGGCTACTGGCAAGCTCC
CTGGTCAAGGAGAGCAGACTAGCCAGACTGCTGCTCAAGGACCTAAGCAAGATGGTATCCTGGCTAAGTTAGGTCGCAAT
CTGACTCAGGAAGCTCGTGATGGTAAGTTAGATCCAGTCATTGGGCGCAATAAGGAAATCCAAGAAACTGCTGAAATCCT
TTCCCGCCGGACTAAGAACAATCCGGTTCTGGTCGGAGATGCCGGAGTTGGTAAGACAGCTGTCGTAGAAGGATTGGCTC
AGGCCATCGTCAATGGTGATGTGCCAGCGGCCATCAAGAACAAGGAAATTATTTCTGTTGATATTTCCGGTCTGGAAGCT
GGGACTCAGTATCGTGGTAGCTTTGAAGAAAATATCCAAAACTTAGTCAATGAAGTCAAGGAAGCCGGCAACATTATCCT
CTTCTTTGATGAAATCCATCAAATCTTGGGAGCAGGATCTACTGGCGGAGACAGCGGTTCCAAGGGCTTGGCGGATATTC
TCAAACCAGCGCTTTCTCGTGGGGAGTTGACCGTTATCGGGGCTACTACTCAGGACGAGTACCGTAACACCATTCTTAAA
AATGCAGCTCTGGCTCGCCGGTTCAATGAAGTCAAGGTCAATGCACCGTCTGCTGAGGATACCTATCAGATTCTTCGAGG
CATTCGGGACCTGTACGAAAAGCACCACAATGTCATCCTGCCGGATGAAGTGCTGAAAGCGGCTGTGGACTACTCTGTTC
AGTATATTCCACAGCGGAGCCTGCCAGACAAGGCGATTGACCTGGTCGACGTGACTGCTGCCCACCTGGCAGCCCAGCAT
CCAGTAACCGATGTTCATGCGGTTGAACATGAGATTGCTGAGCAAAAAGACAAGCAGGAAGCAGCTGTTGAAAAAGAAGA
TTTTGAAGCAGCTCTGAATGCCAAGACCCGCATTGAAGAGCTGGAAAAGAAAATTCAAAACCACACCGAGGATATGAAGG
TTACTGCTACGATCAACGATGTAGCAGAGTCTGTTGAGCGGATGACGGGAGTGCCTGTCTCACAGATGGGTGCCAGCGAC
ATTGAGCGCCTCAAGGGCATGAATGACCGTCTCAAAGCCAAGGTTATTGGTCAAGACAAGGCTGTAGAAGCTGTGGCTAG
GGCTATCCGCCGTAACCGTGCAGGTTTTGATGAAGGCAACCGTCCAATCGGAAGCTTCCTCTTCGTTGGTCCGACAGGTG
TCGGCAAGACTGAGCTGGCTAAGCAACTGGCTCTAGATATGTTCGGTACCAAGGAAGCGATTATCCGTCTGGATATGTCA
GAATACTCCGACCGGACTGCTGTTTCCAAGCTGATTGGTACCACTGCAGGCTATGTCGGCTATGATGATAACAGCAATAC
CTTGACTGAGCGTGTGCGCCGTAATCCTTACTCTATCATCCTCTTGGATGAGATTGAAAAGGCGGATCCACAGGTGATTA
CCCTTCTCCTTCAAGTTCTGGATGACGGTCGTTTGACAGATGGTCAAGGGAATACAGTCAACTTCAAGAACACGGTTATC
ATTGCGACTTCCAATGCCGGATTTGGCTATGAAGCAGGCTTGGAAGAGGATGCAGAAAAGCCTGATCTGATGGATCGACT
CAAAGCTTATTTCCGTCCAGAGTTCCTCAATCGTTTCAATGCAGTTATTGAGTTCTCTCATCTCAAGAAAGAAGATTTGA
TGGAGATTGTGAATCTCATGCTGATTGAAGTAAATCAAACCTTGAGCAAGAAAGAAATTGATCTGGCTGTATCTGATGCA
GCTAAGGAATTCCTGCGCGATGCTGGTTATGACCAGGTCATGGGTGTTCGTCCGCTCCGTCGTGTCATCGAGCAGCAAAT
TCGTGACAAGGTGACTGACTTCCACTTGGATAATCTAGATGCTAAGCACTTGACGGCCGATTTAGAAGATGGTGTCTTGG
TTATCCGGGAAAAAGGCGCTGCCGCATCTGAAGAAGACAAGCAGGCAGAATAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(441-601)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(608-678)

AAA lid domain (AAA_lid_9)

(257-352)

ATPase family associated with various cellular activities (AAA) (AAA)

(116-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7H8UY64

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. cremoris KW2

48.169

100

0.482
  clpE Streptococcus mutans UA159

46.705

98.31

0.459
  clpE Streptococcus pneumoniae Rx1

48.103

92.817

0.446
  clpE Streptococcus pneumoniae D39

48.103

92.817

0.446
  clpE Streptococcus pneumoniae R6

48.103

92.817

0.446
  clpE Streptococcus pneumoniae TIGR4

48.103

92.817

0.446
  clpC Bacillus subtilis subsp. subtilis str. 168

45.538

91.549

0.417
  clpC Streptococcus pneumoniae D39

42.476

89.859

0.382
  clpC Streptococcus pneumoniae TIGR4

42.476

89.859

0.382
  clpC Streptococcus pneumoniae Rx1

42.476

89.859

0.382
  clpC Streptococcus thermophilus LMG 18311

42.492

88.169

0.375
  clpC Streptococcus mutans UA159

42.834

87.465

0.375
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

42.857

86.761

0.372
  clpC Streptococcus thermophilus LMD-9

42.147

87.887

0.37

Multiple sequence alignment