Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   HMU_RS05940 Genome accession   NC_013949
Coordinates   1251775..1252548 (+) Length   257 a.a.
NCBI ID   WP_013023452.1    Uniprot ID   D3UIQ8
Organism   Helicobacter mustelae 12198     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1246775..1257548
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMU_RS05920 (HMU11240) - 1247868..1248266 (+) 399 WP_013023448.1 hypothetical protein -
  HMU_RS05925 (HMU11250) - 1248274..1250490 (+) 2217 WP_013023449.1 endonuclease MutS2 -
  HMU_RS05930 (HMU11260) minD 1250754..1251548 (+) 795 WP_013023450.1 septum site-determining protein MinD -
  HMU_RS05935 (HMU11270) minE 1251545..1251775 (+) 231 WP_013023451.1 cell division topological specificity factor MinE -
  HMU_RS05940 (HMU11280) dprA 1251775..1252548 (+) 774 WP_013023452.1 DNA-processing protein DprA Machinery gene
  HMU_RS05945 (HMU11290) dprB 1252545..1252943 (+) 399 WP_041913181.1 Holliday junction resolvase RuvX Machinery gene
  HMU_RS05950 (HMU11300) - 1253050..1254054 (-) 1005 WP_013023454.1 MraY family glycosyltransferase -
  HMU_RS05955 (HMU11310) - 1254051..1254992 (-) 942 WP_013023455.1 ATPase, T2SS/T4P/T4SS family -
  HMU_RS05960 (HMU11320) - 1254976..1255350 (-) 375 WP_013023456.1 hypothetical protein -
  HMU_RS05965 (HMU11330) - 1255347..1255757 (-) 411 WP_013023457.1 periplasmic protein -
  HMU_RS05970 (HMU11340) - 1255757..1256047 (-) 291 WP_041913182.1 hypothetical protein -
  HMU_RS05975 (HMU11350) - 1256034..1256603 (-) 570 WP_013023459.1 hypothetical protein -
  HMU_RS05980 (HMU11360) - 1256600..1257199 (-) 600 WP_041913183.1 hypothetical protein -
  HMU_RS05985 (HMU11370) - 1257307..1257513 (-) 207 WP_013023461.1 DUF4006 family protein -

Sequence

Protein


Download         Length: 257 a.a.        Molecular weight: 28645.25 Da        Isoelectric Point: 8.4271

>NTDB_id=36708 HMU_RS05940 WP_013023452.1 1251775..1252548(+) (dprA) [Helicobacter mustelae 12198]
MQSHFDYHPLPQIPESLSALKLQQLFYVGRPELLQSSLKIAIVGSRNPNPYARAFVTQLASKLTPHATIISGGALGIDII
AHKAALPHTIMISPSSLDLIYPASNQHIIKEIAARALILSEYEKNTPPRPYSFLQRNRIVIGLSDIVIIPQADLGSGSMQ
SAKMALKLKKPLYVLPHRINESLGTKSLLSQNQARPIYDIEEFLKECEITPNARDEILEFCAQAPDYEVALEKFGNRLLE
YELDGKIRRENGKVIAL

Nucleotide


Download         Length: 774 bp        

>NTDB_id=36708 HMU_RS05940 WP_013023452.1 1251775..1252548(+) (dprA) [Helicobacter mustelae 12198]
ATGCAGAGCCATTTTGATTATCACCCCCTCCCACAAATCCCAGAAAGCCTATCTGCACTCAAGCTGCAGCAGCTTTTTTA
TGTGGGCAGGCCAGAGCTCCTGCAATCCTCTCTAAAAATTGCCATTGTTGGCTCGAGGAATCCCAATCCCTATGCCAGAG
CCTTTGTCACACAGCTTGCAAGCAAACTCACTCCCCATGCCACCATTATTAGCGGTGGGGCGCTTGGGATTGACATCATC
GCACACAAAGCAGCACTCCCCCACACCATCATGATTTCACCAAGCAGCCTAGATCTCATCTATCCTGCTAGCAATCAGCA
CATCATCAAAGAAATTGCCGCGCGCGCTCTGATTTTGAGCGAATATGAAAAAAACACACCTCCTAGGCCCTATAGCTTTT
TGCAACGCAATCGCATTGTGATTGGTCTAAGTGATATTGTCATCATCCCTCAAGCAGATCTAGGCAGTGGAAGCATGCAG
AGTGCAAAAATGGCGCTAAAGCTAAAAAAACCCCTCTATGTCCTTCCCCATCGCATCAATGAAAGCCTTGGCACCAAATC
CCTCCTTTCCCAAAATCAGGCAAGGCCAATCTATGATATTGAGGAATTTCTCAAAGAATGTGAAATTACACCAAATGCCA
GAGATGAGATTTTGGAATTTTGCGCACAAGCTCCAGATTATGAAGTGGCACTGGAAAAATTTGGCAATAGGCTTTTGGAA
TATGAGCTAGATGGCAAGATTAGGCGCGAAAATGGCAAGGTGATTGCGCTGTGA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(24-195)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB D3UIQ8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Helicobacter pylori 26695

53.409

100

0.549
  dprA Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

50.222

87.549

0.44

Multiple sequence alignment