Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   GW576_RS09570 Genome accession   NZ_CP048010
Coordinates   1942239..1942895 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain RUT3575     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1937239..1947895
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GW576_RS09540 (GW576_09515) dcyD 1938118..1939104 (+) 987 WP_001128218.1 D-cysteine desulfhydrase -
  GW576_RS09545 (GW576_09520) tcyL 1939119..1939787 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  GW576_RS09550 (GW576_09525) tcyN 1939784..1940536 (+) 753 WP_001273008.1 L-cystine ABC transporter ATP-binding protein TcyN -
  GW576_RS09555 (GW576_09530) sdiA 1940766..1941488 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  GW576_RS09560 (GW576_09535) yecF 1941556..1941780 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  GW576_RS09565 (GW576_09540) yecU 1941767..1941943 (-) 177 WP_000590347.1 protein YecU -
  GW576_RS24565 - 1942026..1942097 (-) 72 Protein_1817 transcriptional regulator -
  GW576_RS09570 (GW576_09545) letA 1942239..1942895 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  GW576_RS09575 (GW576_09550) uvrC 1942892..1944724 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  GW576_RS09580 (GW576_09555) pgsA 1944781..1945329 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  GW576_RS09600 (GW576_09575) yecA 1945979..1946644 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=367011 GW576_RS09570 WP_000611335.1 1942239..1942895(+) (letA) [Escherichia coli strain RUT3575]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=367011 GW576_RS09570 WP_000611335.1 1942239..1942895(+) (letA) [Escherichia coli strain RUT3575]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486

Multiple sequence alignment