Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/comEC   Type   Machinery gene
Locus tag   MRUB_RS15345 Genome accession   NC_013946
Coordinates   3091046..3093085 (+) Length   679 a.a.
NCBI ID   WP_013015290.1    Uniprot ID   D3PQF9
Organism   Meiothermus ruber DSM 1279     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 3086046..3098085
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MRUB_RS15315 (Mrub_3042) - 3086089..3087693 (-) 1605 WP_013015284.1 acyl-CoA dehydrogenase family protein -
  MRUB_RS15320 (Mrub_3043) - 3087727..3088746 (+) 1020 WP_013015285.1 GntG family PLP-dependent aldolase -
  MRUB_RS15325 (Mrub_3044) - 3088754..3088948 (-) 195 WP_013015286.1 hypothetical protein -
  MRUB_RS15330 (Mrub_3045) - 3089001..3089681 (-) 681 WP_013015287.1 glycerophosphodiester phosphodiesterase -
  MRUB_RS15335 (Mrub_3046) - 3089915..3090652 (+) 738 WP_156113845.1 hypothetical protein -
  MRUB_RS15340 (Mrub_3047) - 3090699..3091049 (+) 351 WP_013015289.1 helix-hairpin-helix domain-containing protein -
  MRUB_RS15345 (Mrub_3048) comA/comEC 3091046..3093085 (+) 2040 WP_013015290.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  MRUB_RS15350 (Mrub_3049) - 3093087..3093905 (-) 819 WP_013015291.1 ParB/RepB/Spo0J family partition protein -
  MRUB_RS15355 (Mrub_3050) - 3093889..3094653 (-) 765 WP_036198776.1 ParA family protein -
  MRUB_RS15360 (Mrub_3051) rsmG 3094647..3095375 (-) 729 WP_013015293.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  MRUB_RS15365 (Mrub_3052) mnmG 3095450..3097258 (-) 1809 WP_041654092.1 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG -

Sequence

Protein


Download         Length: 679 a.a.        Molecular weight: 74242.23 Da        Isoelectric Point: 9.4932

>NTDB_id=36689 MRUB_RS15345 WP_013015290.1 3091046..3093085(+) (comA/comEC) [Meiothermus ruber DSM 1279]
MIPLALGAGALLGALSQLTPWAFLGLLAGLGLPQSARWLGLGAYILVTLHLGLAQDPWASQIGQWVRIEGTLREGFLHTP
QGRLYVHYFPNLQDGRYVLEGHLLRPSNKRNPGGFDQQTWLRGLGVTAVLRARQVVHYEPLPAGPHQWLQKQLVAGLSAP
VAALVTALTLGERRELGEAYEAFQQAGLAHTLALSGLHVAILTGFFVLLLYPLGRWRYPAALLLLLLYLWLVEPQPSLVR
AVIMAGFVLMGLFMGRGRVAVLPALSLALFVQLLLEPRTLLSLSAQLSYLAVLGMALVLPHLPRLEGWKQWVWSSVSVTL
AAQILILPLLLHHFHQLPLISPVANLLVLPLLSLLVPLGFLKLLMGGLLAWPTEILGSLVLGLVGWLSNGPLLRWGEITP
VGFILYYLGLLPLLLGLYGRLRWPHATGLAATAALASILSSYPPRAELWQLDVGQGDAILLRLPGRVEILVDGGRDWAYP
RLEQALRALGVDDLDLLIATHPDGDHVEAQLKVIRDFPVGALVSGPRAQGVALDDALHLAAHQRGIPVFFARRGSQLTLA
GARLHFLGPQGDELEDNERSLVFVLEYKNHKILFTGDAPVSAEVRWSAERVDILKVGHHGSETSTSDHLLQHFRPKLALI
GVGNNPYGHPSRAVLERLNQYGVQIRRTDIEGAIRIPLP

Nucleotide


Download         Length: 2040 bp        

>NTDB_id=36689 MRUB_RS15345 WP_013015290.1 3091046..3093085(+) (comA/comEC) [Meiothermus ruber DSM 1279]
ATGATCCCCCTGGCTCTGGGCGCTGGGGCCCTGCTGGGGGCTCTCAGCCAGCTAACCCCCTGGGCCTTCCTGGGCCTGCT
AGCAGGGCTTGGGCTCCCTCAGTCTGCGCGCTGGCTTGGTTTGGGAGCTTACATTCTGGTCACCCTGCACCTGGGTTTAG
CCCAGGATCCCTGGGCTTCCCAGATAGGACAGTGGGTGCGGATCGAAGGCACTCTTCGAGAGGGTTTTTTACACACCCCA
CAAGGGCGTTTATATGTGCATTACTTTCCCAATTTGCAGGATGGCCGTTACGTTTTGGAAGGCCACCTGCTGCGCCCCTC
AAACAAGCGCAACCCCGGGGGCTTTGATCAGCAAACCTGGCTGCGCGGCCTGGGGGTTACGGCAGTATTACGAGCTCGGC
AGGTTGTGCATTACGAGCCTTTACCGGCAGGCCCCCACCAATGGCTGCAAAAGCAGCTTGTGGCCGGGCTCTCCGCTCCA
GTAGCCGCCCTGGTCACGGCCCTGACCCTTGGGGAACGTCGCGAGTTGGGTGAGGCCTATGAGGCATTTCAGCAAGCCGG
CCTGGCCCATACCCTGGCCCTATCTGGTTTACACGTGGCAATCCTGACCGGCTTTTTTGTGCTCTTGCTCTATCCGCTGG
GCAGGTGGCGCTACCCTGCAGCCTTGCTTTTATTGCTGCTGTATCTGTGGCTTGTAGAGCCCCAGCCTTCGCTGGTACGG
GCAGTGATTATGGCGGGCTTTGTGTTGATGGGGCTGTTTATGGGGCGCGGCCGGGTAGCGGTCTTACCCGCTCTGTCGCT
GGCTTTATTCGTTCAGTTGTTGCTCGAGCCGCGTACCCTGCTCAGCCTTTCGGCACAGCTTTCCTATCTGGCCGTGCTGG
GCATGGCCCTGGTGCTGCCGCACCTGCCCAGGCTCGAGGGCTGGAAACAGTGGGTCTGGTCCTCGGTTAGCGTCACCCTT
GCAGCACAAATTCTGATCCTTCCCCTCTTGCTCCATCACTTCCACCAACTGCCGCTCATCTCTCCCGTTGCAAATCTGTT
GGTGCTGCCCTTGCTAAGCCTCCTGGTTCCCCTAGGCTTTCTCAAGCTACTGATGGGGGGTTTGCTGGCCTGGCCCACCG
AGATTCTCGGTTCGCTGGTTCTGGGACTGGTTGGGTGGCTGTCCAACGGCCCCTTGCTGCGCTGGGGTGAGATAACTCCT
GTAGGGTTCATCCTGTACTACCTTGGCCTTCTCCCATTACTGCTAGGCCTTTATGGTCGTCTTCGCTGGCCGCATGCAAC
GGGGCTTGCTGCCACAGCCGCGCTGGCCTCCATCTTGTCCAGTTACCCGCCCCGCGCCGAGCTCTGGCAGCTCGATGTGG
GCCAGGGCGATGCGATCCTGCTACGCCTTCCCGGCAGGGTAGAAATCTTAGTGGATGGGGGGCGCGACTGGGCTTATCCC
CGGCTAGAACAAGCCTTGCGGGCCTTGGGTGTGGACGATCTCGATCTGCTCATCGCCACCCACCCCGATGGGGATCATGT
GGAGGCCCAGTTGAAGGTTATACGGGATTTTCCAGTTGGTGCATTGGTTAGTGGGCCCAGGGCCCAGGGCGTTGCCTTGG
ATGATGCCTTACACCTGGCTGCACACCAGCGTGGAATCCCGGTCTTTTTTGCGCGCAGGGGAAGCCAGCTAACCCTGGCT
GGAGCCCGCCTCCATTTCTTGGGGCCGCAAGGTGACGAGCTCGAGGACAACGAGCGCAGTTTGGTTTTCGTGTTGGAGTA
TAAGAATCATAAGATACTCTTTACCGGTGATGCGCCCGTCTCAGCCGAGGTGCGCTGGTCTGCCGAGAGGGTGGATATCC
TAAAGGTGGGTCATCATGGTTCTGAGACCAGCACCAGTGATCACCTATTGCAGCATTTCCGTCCCAAGCTAGCCTTAATC
GGTGTGGGAAATAATCCGTATGGTCATCCGTCGAGGGCTGTACTAGAACGCCTAAACCAGTACGGCGTACAAATTCGACG
CACCGACATCGAGGGGGCCATACGGATTCCCTTGCCTTGA

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(452-639)

Competence protein (Competence)

(168-417)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB D3PQF9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/comEC Thermus thermophilus HB27

48.296

99.411

0.48
  comEC Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539

40.819

97.054

0.396

Multiple sequence alignment