Detailed information NTG0366459

Bioinformatically predicted

Overview

• Name: comA
• Type: Machinery gene
• Locus tag: FF962_RS12120
• Genome accession: NZ_CP040684
• Coordinates: 2522627..2524852 (-)
• Length: 741 a.a.
• NCBI ID: WP_023100928.1
• Uniprot ID: A0A509JMW0
• Organism: Pseudomonas aeruginosa strain C79
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2517627..2529852

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FF962_RS12085 (FF962_12085)	murB	2518017..2519036 (-)	1020	WP_021265002.1	UDP-N-acetylmuramate dehydrogenase	-
FF962_RS12090 (FF962_12090)	-	2519033..2519497 (-)	465	WP_003106924.1	low molecular weight protein-tyrosine-phosphatase	-
FF962_RS12095 (FF962_12095)	kdsB	2519497..2520261 (-)	765	WP_003091155.1	3-deoxy-manno-octulosonate cytidylyltransferase	-
FF962_RS12100 (FF962_12100)	-	2520261..2520446 (-)	186	WP_003091157.1	Trm112 family protein	-
FF962_RS12105 (FF962_12105)	lpxK	2520484..2521482 (-)	999	WP_003130692.1	tetraacyldisaccharide 4'-kinase	-
FF962_RS12110 (FF962_12110)	-	2521482..2521922 (-)	441	WP_003091161.1	ExbD/TolR family protein	-
FF962_RS12115 (FF962_12115)	exbB	2521919..2522554 (-)	636	WP_003091163.1	MotA/TolQ/ExbB proton channel family protein	Machinery gene
FF962_RS12120 (FF962_12120)	comA	2522627..2524852 (-)	2226	WP_023100928.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
FF962_RS12125 (FF962_12125)	-	2524983..2525516 (+)	534	WP_003091165.1	DUF2062 domain-containing protein	-
FF962_RS12130 (FF962_12130)	-	2525592..2526836 (-)	1245	WP_003105198.1	lipoprotein-releasing ABC transporter permease subunit	-
FF962_RS12135 (FF962_12135)	lolD	2526906..2527589 (-)	684	WP_003091168.1	lipoprotein-releasing ABC transporter ATP-binding protein LolD	-
FF962_RS12140 (FF962_12140)	-	2527582..2528832 (-)	1251	WP_015502671.1	lipoprotein-releasing ABC transporter permease subunit	-
FF962_RS12145 (FF962_12145)	-	2528935..2529534 (+)	600	WP_003091172.1	PilZ domain-containing protein	-
FF962_RS12150 (FF962_12150)	-	2529544..2529852 (+)	309	WP_021265003.1	hypothetical protein	-

Sequence

Protein

• Length: 741 a.a.
• Molecular weight: 79964.54 Da
• Isoelectric Point: 10.5155

>NTDB_id=366459 FF962_RS12120 WP_023100928.1 2522627..2524852(-) (comA) [Pseudomonas aeruginosa strain C79]
MRLGLPALAAGLLALRFLAELPSVGWLLGMAAAGLLLLFGRLYWLGLFLLGFAWACGSAQVALDGRLAAELDGRTLWLEG
RVVDLPASGEGVTRFRLEEVSAARGVLLPERLRLSWRGAPPLMGGERWRLAVTLKRPRGLVNAAGFDYEAWLLAQRVGAV
GTVKAGQRLQPASGLDAWRDAWRQRLLAVDAQGRGAALAALVLGDGSGLSAAEWRMFQDTGTVHLMVISGSHISLLAGML
YGLVAALHRLGCWPRRLPWLPCACALGLLGAWSYGLMAGFEVPVRRACLMVSLALVWRLRFRHLGLLTPLLGTLVLVLLV
EPLASLQAGFWLSFLAVALLLWLFAGRLGRWRWWAAWGRAQWGMALGLAMPLLALGLPLSLSGAPANLLAVPWIELLVVP
PALAGSLLLWVPGLGEGLLRAAGVSLDLLFRALGLLAGLAEAWQPPAAAAWSVALGMLGALCWLAPAGLPLRALGAALLL
PALLPSSPPVEWGRAEVRVLDVGQGLAVLVRTREHALLYDSGARQGAFDMGERVVVPVLRSLDLRRLDGLLLSHADNDHA
GGAPTVASRFPPGWLVSGEPARLPSPLFADSCDERRWSWDGVVFEQWAWAQAGDSNDRSCVLRVEADGEVLLLTGDISRA
AEHAWLARQADPRVDWLLAPHHGSRSSSGVAFVLRTRPRHVLVSRGWRNAFGHPHGEVMERYARVAAQVHDTARDGALTF
LLGSRGGARRERDSAHFWREK

Nucleotide

• Length: 2226 bp

>NTDB_id=366459 FF962_RS12120 WP_023100928.1 2522627..2524852(-) (comA) [Pseudomonas aeruginosa strain C79]
ATGCGCCTGGGATTGCCAGCTCTCGCCGCGGGGCTGCTGGCCCTGCGCTTCCTGGCGGAATTGCCGTCGGTCGGCTGGCT
GCTGGGCATGGCCGCCGCCGGACTGTTGCTGCTGTTCGGCCGGCTGTACTGGCTGGGGTTGTTCCTGCTCGGGTTCGCCT
GGGCCTGCGGCTCGGCGCAAGTCGCCCTGGACGGACGCCTGGCCGCCGAGCTGGATGGTCGCACCCTTTGGCTGGAGGGG
CGTGTGGTCGATCTGCCGGCGAGCGGCGAGGGCGTCACGCGCTTCCGGCTGGAGGAGGTCAGCGCTGCGCGGGGCGTGCT
TCTTCCCGAGCGTCTGCGCCTGAGCTGGCGCGGCGCGCCGCCGCTGATGGGCGGCGAACGCTGGCGCCTGGCGGTGACCC
TGAAACGCCCCCGCGGCCTGGTGAACGCGGCGGGTTTCGACTACGAGGCCTGGTTGTTGGCGCAGCGGGTCGGTGCTGTG
GGCACGGTGAAGGCGGGCCAACGCCTGCAGCCGGCCAGCGGCCTGGATGCCTGGCGCGATGCCTGGCGCCAGCGCCTGCT
GGCGGTCGACGCACAGGGGCGCGGCGCCGCCCTGGCGGCGCTGGTGCTGGGGGATGGCTCGGGATTGAGCGCGGCCGAGT
GGCGAATGTTCCAGGACACCGGCACCGTGCATCTGATGGTCATCTCCGGTTCGCATATCTCGTTGCTGGCAGGGATGCTC
TATGGCCTGGTGGCGGCCTTGCATCGCCTGGGCTGCTGGCCGCGGCGCTTGCCCTGGCTGCCCTGTGCCTGCGCCCTGGG
TTTGCTTGGTGCCTGGAGCTACGGGTTGATGGCGGGTTTCGAGGTCCCGGTGCGGCGTGCTTGCCTGATGGTCAGCCTGG
CGCTGGTCTGGCGCCTGCGTTTCCGCCACCTGGGCTTGCTGACCCCGCTGCTGGGAACGCTGGTGCTGGTCTTGCTGGTC
GAGCCGCTGGCCAGCCTGCAGGCGGGGTTCTGGCTGTCGTTCCTGGCGGTTGCCCTGCTGCTCTGGCTGTTCGCCGGGCG
CCTTGGGCGCTGGCGCTGGTGGGCGGCCTGGGGGCGGGCGCAGTGGGGGATGGCGCTGGGGCTGGCGATGCCGCTGCTGG
CGCTGGGCCTGCCGTTGAGCCTGAGCGGAGCGCCGGCCAACCTGCTGGCGGTGCCTTGGATCGAACTGCTGGTAGTGCCC
CCGGCCCTGGCTGGGAGCCTGCTGCTATGGGTGCCCGGGCTGGGCGAGGGGCTGCTTCGCGCCGCTGGCGTTTCGCTGGA
CCTGCTGTTTCGTGCACTTGGCCTGCTGGCGGGCCTGGCCGAGGCGTGGCAGCCACCCGCCGCAGCGGCCTGGAGCGTAG
CGCTGGGCATGCTCGGCGCGCTCTGCTGGCTGGCGCCGGCTGGCTTGCCGTTGCGTGCCCTCGGTGCCGCGTTGCTACTG
CCGGCGTTGTTGCCGTCATCGCCGCCTGTCGAATGGGGGCGGGCGGAAGTGCGGGTGCTGGACGTCGGCCAGGGGCTGGC
CGTGCTGGTGCGTACCCGGGAGCATGCCTTGCTCTATGACAGCGGTGCGCGGCAGGGGGCGTTCGACATGGGCGAGCGGG
TGGTGGTGCCGGTGCTGCGCAGCCTGGACCTGCGGCGCCTGGACGGCCTGTTGCTGAGCCATGCCGACAACGACCATGCA
GGCGGTGCTCCTACGGTCGCTTCCCGATTCCCGCCGGGTTGGCTGGTCAGCGGCGAACCCGCGCGCCTGCCTTCGCCGTT
GTTCGCGGACAGCTGCGACGAGCGGCGCTGGTCCTGGGATGGCGTGGTTTTCGAACAGTGGGCATGGGCGCAGGCCGGCG
ACAGCAACGACCGCTCCTGCGTGCTGAGGGTCGAGGCCGATGGCGAAGTCCTGCTGCTGACCGGGGACATCTCGCGTGCG
GCCGAGCATGCCTGGCTGGCGCGACAGGCCGATCCGCGGGTCGACTGGTTGCTGGCGCCGCATCACGGCAGCCGCAGCTC
CTCCGGAGTCGCCTTCGTGTTGCGTACGCGGCCTCGCCATGTGCTGGTCTCGCGAGGTTGGCGCAACGCCTTCGGCCATC
CCCATGGCGAAGTGATGGAACGTTACGCGAGGGTCGCCGCGCAGGTCCACGACACGGCACGCGACGGTGCCCTGACGTTT
CTCCTCGGAAGCCGTGGCGGCGCACGCCGGGAGCGTGATTCGGCGCACTTCTGGCGGGAAAAATGA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (21-168)

• Metallo-beta-lactamase superfamily (Lactamase_B) (501-666)

• Competence protein (Competence) (201-464)

3D structure

• AlphaFold DB: A0A509JMW0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Pseudomonas stutzeri DSM 10701	59.223	97.301	0.576
comA	Ralstonia pseudosolanacearum GMI1000	35.742	100	0.367