Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   M594_RS07675 Genome accession   NZ_CP047883
Coordinates   1566200..1568047 (-) Length   615 a.a.
NCBI ID   WP_173876420.1    Uniprot ID   -
Organism   Streptococcus mitis strain S022-V3-A4     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1561200..1573047
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M594_RS07650 (M594_07675) - 1562130..1562417 (-) 288 WP_173876415.1 rhodanese-like domain-containing protein -
  M594_RS07655 (M594_07680) - 1562532..1563110 (-) 579 WP_173876416.1 uracil-DNA glycosylase family protein -
  M594_RS07660 (M594_07685) pepV 1563164..1564564 (-) 1401 WP_173876417.1 dipeptidase PepV -
  M594_RS07665 (M594_07690) - 1564577..1565182 (-) 606 WP_173876418.1 nitroreductase family protein -
  M594_RS07670 (M594_07695) - 1565356..1566210 (-) 855 WP_173876419.1 metallophosphoesterase family protein -
  M594_RS07675 (M594_07700) uvrC 1566200..1568047 (-) 1848 WP_173876420.1 excinuclease ABC subunit UvrC Machinery gene
  M594_RS07680 (M594_07705) - 1568086..1568787 (-) 702 WP_173876421.1 M57 family metalloprotease -
  M594_RS07685 (M594_07710) - 1568850..1569629 (-) 780 WP_173876422.1 alpha/beta hydrolase -
  M594_RS07690 (M594_07715) - 1569698..1571359 (-) 1662 WP_000065614.1 ribonuclease J -
  M594_RS07695 (M594_07720) - 1571574..1572922 (+) 1349 WP_173875850.1 IS3 family transposase -

Sequence

Protein


Download         Length: 615 a.a.        Molecular weight: 70698.15 Da        Isoelectric Point: 8.7196

>NTDB_id=366326 M594_RS07675 WP_173876420.1 1566200..1568047(-) (uvrC) [Streptococcus mitis strain S022-V3-A4]
MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSYFRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEIN
LIKENKPKYNIMLKDDKSYPFIKITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
YYHIGQCMAHTICKKDESYFKSMAQEVSDFLKGQDDKIIDDLKGKMETAAQTMEFERAAEYRDLIQAIGTLRTKQRVMAK
DLQNRDVFGYYADKGWMCVQVFFVRQGKLIERDVNLFPYYNDPDEDFLTYVGQFYQEKSHLVPNEVLIPRDIDEEAVKAL
VDTKILKPQRGEKKQLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGTSPVSAMVV
FVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREGLTPPDLIVIDGGQGQVNIAKQVIQEELGLDIPIAGLQ
KNDKHQTHELLFGDPLEVVELSRNSQEFFLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSL
TKIKEASVDEIVEVGVPRAVAEAVQRKLNPQEEVELAQVAEERVDYQTEGDHHEP

Nucleotide


Download         Length: 1848 bp        

>NTDB_id=366326 M594_RS07675 WP_173876420.1 1566200..1568047(-) (uvrC) [Streptococcus mitis strain S022-V3-A4]
ATGAATAACTTGATTAAATCAAAACTAGAGCTCTTGCCGACCAGCCCTGGTTGCTACATTCACAAGGATAAAAACGGTAC
CATTATCTATGTAGGAAAGGCTAAAAATCTGCGTAACCGCGTGAGGTCTTATTTCCGTGGAAGTCATGATACCAAAACAG
AGGCCTTGGTGTCTGAAATTGTGGATTTTGAATTTATCGTTACGGAGTCTAATATTGAGGCACTTCTCCTAGAAATCAAT
CTGATCAAGGAAAATAAGCCTAAGTACAATATCATGCTCAAGGATGATAAGTCTTATCCTTTCATCAAAATTACCAATGA
GCGCTATCCTCGTTTGATTATCACCCGTCAGGTCAAGAAGGATGGAGGTCTCTATTTTGGTCCCTATCCAGATGTGGGAG
CAGCCAATGAAATCAAGCGACTACTGGATCGGATTTTCCCTTTTCGTAAGTGTACCAATCCTCCTTCTAAGGTTTGTTTT
TATTACCATATCGGTCAATGTATGGCCCACACTATCTGTAAGAAGGATGAGTCCTACTTCAAGTCTATGGCTCAGGAGGT
TTCTGATTTCCTAAAAGGGCAAGATGACAAAATCATTGATGACCTAAAGGGCAAGATGGAAACGGCAGCCCAGACTATGG
AATTTGAACGTGCGGCGGAATACCGTGACCTAATTCAAGCCATTGGAACGCTTCGAACCAAGCAACGGGTCATGGCCAAG
GATCTCCAAAATCGGGATGTCTTTGGTTACTATGCGGACAAGGGATGGATGTGTGTTCAGGTTTTCTTTGTCCGTCAGGG
AAAGCTTATTGAGCGCGATGTCAATCTTTTCCCTTATTATAATGATCCGGATGAGGACTTCTTGACCTACGTGGGACAAT
TCTATCAAGAAAAATCCCACCTGGTTCCCAATGAGGTACTAATTCCGCGGGATATTGACGAAGAAGCTGTCAAGGCTTTG
GTAGACACCAAGATTCTTAAGCCTCAGCGTGGAGAGAAAAAGCAACTGGTCAATTTGGCTATAAAGAATGCTCGAGTCAG
TCTAGAGCAGAAGTTCAATTTGTTAGAAAAATCTGTCGAAAAGACACAAGGAGCTATTGAAAATCTAGGACGCTTGCTCC
AAATTCCGACCCCAGTCCGCATCGAATCCTTCGATAACTCCAACATCATGGGAACTAGCCCTGTTTCTGCCATGGTGGTC
TTTGTCAACGGAAAACCTAGTAAGAAGGATTACCGTAAGTATAAAATCAAGACCGTAGTCGGGCCAGACGACTATGCCAG
TATGAGAGAAGTCATTCGCAGGCGCTATGGTCGAGTACAGCGTGAGGGATTAACGCCACCGGACTTGATTGTCATTGATG
GGGGACAGGGTCAAGTTAATATCGCCAAGCAAGTCATCCAAGAGGAGCTGGGCTTGGATATTCCAATTGCTGGGCTTCAA
AAGAACGACAAGCATCAAACCCATGAGCTGCTCTTCGGAGATCCGCTTGAGGTGGTGGAGTTATCTCGTAATTCTCAGGA
ATTTTTCCTTTTGCAACGCATTCAAGATGAGGTGCACCGCTTTGCCATTACTTTCCACCGCCAACTGCGCTCCAAAAATT
CCTTTTCTTCACAACTGGATGGAATTGACGGTCTGGGACCTAAACGCAAGCAGAATCTCATGAAACATTTCAAGTCTCTG
ACTAAAATCAAGGAAGCCAGTGTGGATGAGATTGTCGAAGTTGGAGTACCGAGAGCAGTAGCAGAGGCTGTGCAAAGAAA
GTTGAACCCGCAGGAAGAAGTGGAATTAGCTCAAGTGGCGGAAGAAAGAGTAGATTATCAAACAGAAGGAGATCATCATG
AACCATAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(196-228)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)

GIY-YIG catalytic domain (GIY-YIG)

(17-90)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

97.073

100

0.971
  uvrC Streptococcus pneumoniae R6

96.748

100

0.967
  uvrC Streptococcus pneumoniae D39

96.748

100

0.967