Detailed information NTG0365840

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: FF957_RS14350
• Genome accession: NZ_CP040619
• Coordinates: 2768519..2769406 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain J01
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2763519..2774406

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FF957_RS14315 (FF957_14315)	-	2763538..2763630 (+)	93	WP_010956583.1	hypothetical protein	-
FF957_RS14320 (FF957_14320)	-	2763738..2764235 (-)	498	WP_001065268.1	glutathione peroxidase	-
FF957_RS14325 (FF957_14325)	-	2764245..2764505 (-)	261	WP_001789910.1	hypothetical protein	-
FF957_RS14335 (FF957_14335)	-	2764887..2765000 (-)	114	WP_011447078.1	hypothetical protein	-
FF957_RS14340 (FF957_14340)	-	2765659..2767659 (-)	2001	WP_000776751.1	ABC transporter permease	-
FF957_RS14345 (FF957_14345)	-	2767656..2768411 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
FF957_RS14350 (FF957_14350)	braS	2768519..2769406 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
FF957_RS14355 (FF957_14355)	braR	2769417..2770082 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
FF957_RS14360 (FF957_14360)	-	2770108..2770308 (-)	201	WP_000604728.1	hypothetical protein	-
FF957_RS14365 (FF957_14365)	-	2770506..2771930 (+)	1425	WP_000953744.1	alkaline phosphatase	-
FF957_RS15430 (FF957_14370)	-	2771990..2772091 (-)	102	WP_000731972.1	SE2200 family small protein	-
FF957_RS14375 (FF957_14375)	-	2772213..2772668 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
FF957_RS14380 (FF957_14380)	-	2772913..2773674 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=365840 FF957_RS14350 WP_000143419.1 2768519..2769406(-) (braS) [Staphylococcus aureus strain J01]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=365840 FF957_RS14350 WP_000143419.1 2768519..2769406(-) (braS) [Staphylococcus aureus strain J01]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997