Detailed information NTG0365027

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: FC605_RS12945
• Genome accession: NZ_CP040528
• Coordinates: 2513091..2515421 (-)
• Length: 776 a.a.
• NCBI ID: WP_080529559.1
• Uniprot ID: -
• Organism: Bacillus subtilis strain PR10
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2508091..2520421

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FC605_RS12910 (FC605_12910)	yqxA	2508430..2508768 (-)	339	WP_038429322.1	YqxA family protein	-
FC605_RS12915 (FC605_12915)	spoIIP	2508785..2509990 (-)	1206	WP_038429323.1	spore autolysin SpoIIP	-
FC605_RS12920 (FC605_12920)	gpr	2510053..2511159 (-)	1107	WP_014480309.1	GPR endopeptidase	-
FC605_RS12925 (FC605_12925)	rpsT	2511363..2511629 (+)	267	WP_003229989.1	30S ribosomal protein S20	-
FC605_RS12930 (FC605_12930)	holA	2511644..2512687 (-)	1044	WP_029317888.1	DNA polymerase III subunit delta	-
FC605_RS12935 (FC605_12935)	-	2512727..2512876 (-)	150	WP_003229985.1	hypothetical protein	-
FC605_RS12940 (FC605_12940)	yqzM	2512917..2513051 (+)	135	WP_003229983.1	YqzM family protein	-
FC605_RS12945 (FC605_12945)	comEC	2513091..2515421 (-)	2331	WP_080529559.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
FC605_RS12950 (FC605_12950)	comEB	2515425..2515994 (-)	570	WP_003229978.1	ComE operon protein 2	-
FC605_RS12955 (FC605_12955)	comEA	2516061..2516678 (-)	618	WP_080529560.1	competence protein ComEA	Machinery gene
FC605_RS12960 (FC605_12960)	comER	2516762..2517583 (+)	822	WP_014480313.1	late competence protein ComER	-
FC605_RS12965 (FC605_12965)	yqeM	2517649..2518392 (-)	744	WP_029317885.1	class I SAM-dependent methyltransferase	-
FC605_RS12970 (FC605_12970)	rsfS	2518389..2518745 (-)	357	WP_014480315.1	ribosome silencing factor	-
FC605_RS12975 (FC605_12975)	yqeK	2518763..2519323 (-)	561	WP_014480316.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
FC605_RS12980 (FC605_12980)	nadD	2519313..2519882 (-)	570	WP_004398676.1	nicotinate-nucleotide adenylyltransferase	-
FC605_RS12985 (FC605_12985)	yhbY	2519894..2520184 (-)	291	WP_003226133.1	ribosome assembly RNA-binding protein YhbY	-

Sequence

Protein

• Length: 776 a.a.
• Molecular weight: 86579.15 Da
• Isoelectric Point: 7.3649

>NTDB_id=365027 FC605_RS12945 WP_080529559.1 2513091..2515421(-) (comEC) [Bacillus subtilis strain PR10]
MRNSRLLLPMAAASATAGITAAAYFPAIFLFILFLLIILIKTRHAFLIIVCFFSFILFFVLYAVTDSQNVSSYRQGTYQF
KAVIDTIPKIDGDRMSMMVETPDKEKWAAAYRIQSAGEKEQLLYIEPGMSCELTGTLEEPNHATVPGAFDYNEYLYRQHI
HWNYSVTSIQNCSEPENFKYKVLSLRKHIISFTNSLLPPGSAGIVQALTVGDRFYVEDEVLTAYQKLGVVHLLAISGLHV
GILTAGLFYIMIRLGITREKASILLLLFLPLYVMLTGAAPSVLRAALMSGVYLAGSLVKWRVHSATAICLSYIVLLLFNP
YHLFEAGFQLSFAVSFSLILSSSIFQQVKTSLGQLTIVSLIAQLGSLPILLYHFHQFSIISVPMNMLMVPFYTFCILPGA
VAGVLLLSLSASFGRLFFSWFDLLISWTNRLITNIADVDVFTIMIAHPAPVLLFLFTVTIILLLMAIEKRSLSQLMITGG
ICCTVLFLLFIYPCLSSEGEVDMIDIGQGDSMFVGAPHQRGRVLIDTGGTLSYSSEPWREKQHPFALGEKVLIPFLTAKG
IKQLDALILTHADQDHIGEAETLLKHHKVKRLVIPKGFVSEPKDEKVLQTAREEGVTIEEVKRGDVLQIKDLQFHVLSPG
APDPSSKNNSSLVLWMETGVLSWILTGDLEKEGEQEVMDVFPNIKADVLKVGHHGSKGSTGEEFIQQLQPKTAIISAGKN
NRYHHPHQKVLQLLQRHSIRVLRTDQNGTIQYRYKNRVGTFSVYPPYDTSDITETN

Nucleotide

• Length: 2331 bp

>NTDB_id=365027 FC605_RS12945 WP_080529559.1 2513091..2515421(-) (comEC) [Bacillus subtilis strain PR10]
ATGCGTAATTCGCGTTTGTTATTGCCTATGGCGGCAGCTTCGGCAACGGCTGGAATTACTGCCGCCGCTTATTTCCCCGC
TATTTTTCTTTTCATCCTCTTTCTCCTCATCATTTTAATCAAAACGAGGCACGCTTTTCTCATTATTGTTTGTTTCTTCT
CTTTTATATTGTTTTTTGTACTGTATGCAGTCACAGATTCTCAGAATGTCTCTTCCTATCGGCAGGGAACCTATCAATTC
AAGGCAGTGATTGACACTATTCCCAAAATTGACGGCGACCGTATGTCTATGATGGTTGAGACACCTGATAAGGAAAAATG
GGCTGCTGCGTATCGCATTCAGTCTGCTGGTGAAAAAGAACAGCTGTTATACATAGAACCAGGAATGTCATGTGAGTTGA
CTGGTACATTGGAAGAACCGAATCACGCAACTGTGCCGGGTGCATTTGATTATAACGAGTATCTTTATCGGCAGCATATT
CATTGGAACTACTCTGTCACGTCTATCCAAAACTGCAGCGAACCTGAAAATTTTAAGTACAAGGTGCTCAGCTTGAGAAA
ACATATCATATCATTCACAAACAGCCTTTTGCCTCCTGGTTCAGCAGGGATTGTACAGGCACTTACAGTTGGTGACAGAT
TTTATGTGGAGGATGAAGTGCTTACCGCGTATCAAAAGCTTGGTGTTGTCCATCTCTTGGCAATATCAGGACTCCATGTG
GGGATTTTGACAGCAGGTTTGTTTTATATCATGATTCGCCTTGGTATAACTAGAGAAAAGGCGTCAATTCTGTTGCTGTT
ATTTCTGCCACTCTATGTGATGTTGACCGGCGCTGCTCCTTCAGTGCTACGCGCCGCTCTCATGTCGGGTGTTTACTTAG
CTGGAAGCCTTGTCAAATGGCGTGTCCACTCTGCAACTGCAATTTGCCTTTCATACATCGTCCTTCTGCTCTTCAATCCT
TATCATCTCTTTGAAGCCGGTTTTCAGCTATCGTTCGCCGTCAGTTTTTCTTTAATTCTATCCTCTTCTATTTTTCAGCA
GGTTAAAACCTCCTTGGGACAGCTGACAATTGTATCACTCATCGCTCAGCTGGGCTCGCTTCCGATTCTTCTATATCATT
TTCATCAGTTTTCTATCATCAGCGTACCGATGAATATGTTGATGGTACCATTTTATACCTTCTGTATTTTGCCGGGAGCT
GTAGCAGGTGTTCTTCTATTAAGTCTTTCCGCTTCGTTTGGGAGATTGTTTTTCAGTTGGTTTGATTTATTGATAAGCTG
GACCAATAGGCTAATCACAAACATTGCAGATGTTGATGTGTTCACGATTATGATCGCACATCCTGCACCTGTTTTGCTTT
TTTTATTCACGGTCACGATCATCCTATTGCTTATGGCGATTGAAAAACGCTCCTTGTCGCAGTTGATGATAACCGGCGGC
ATTTGCTGCACGGTGCTGTTTCTGCTCTTTATATATCCGTGTCTTAGTTCCGAAGGAGAAGTGGATATGATAGATATTGG
ACAGGGTGACAGCATGTTTGTAGGTGCTCCGCATCAGCGGGGTCGTGTCTTAATTGATACCGGCGGCACTTTGTCTTACT
CGTCAGAGCCTTGGCGCGAAAAACAGCATCCGTTTGCACTGGGGGAAAAGGTGCTGATTCCGTTTTTAACTGCTAAGGGA
ATCAAACAGCTTGACGCTTTAATTCTGACGCACGCTGACCAAGATCATATCGGAGAGGCGGAGACTCTGCTGAAGCATCA
TAAAGTAAAGCGCCTCGTGATTCCGAAAGGGTTCGTTTCTGAACCTAAAGATGAGAAAGTGCTGCAGACAGCCAGAGAAG
AGGGAGTGACAATTGAAGAGGTGAAGCGAGGCGATGTATTGCAAATAAAGGATTTGCAGTTCCATGTACTGTCACCTGGA
GCACCTGATCCGTCAAGCAAAAATAATTCCTCTCTCGTTCTGTGGATGGAGACGGGCGTTCTGAGCTGGATTTTGACGGG
TGATCTGGAGAAAGAAGGGGAACAGGAGGTGATGGACGTGTTTCCAAATATTAAAGCAGATGTCTTAAAGGTGGGGCACC
ATGGGAGCAAAGGCTCTACCGGTGAAGAATTCATCCAACAGCTTCAGCCGAAAACGGCCATTATCTCAGCCGGGAAAAAC
AATCGGTACCATCATCCTCATCAAAAAGTTCTGCAACTATTACAGAGACATTCTATCCGCGTGCTGCGAACAGATCAAAA
CGGAACGATCCAATATAGATACAAAAACAGAGTTGGAACCTTTTCTGTCTATCCTCCATATGATACATCAGATATAACAG
AGACGAACTAA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (20-170)

• Competence protein (Competence) (208-469)

• Metallo-beta-lactamase superfamily (Lactamase_B) (507-718)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Bacillus subtilis subsp. subtilis str. 168	98.067	100	0.981