Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   E3S96_RS04370 Genome accession   NZ_CP047828
Coordinates   880999..882780 (-) Length   593 a.a.
NCBI ID   WP_160190551.1    Uniprot ID   -
Organism   Staphylococcus aureus strain UP_1073     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 875999..887780
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3S96_RS04350 (E3S96_04350) racE 876388..877188 (-) 801 WP_001039660.1 glutamate racemase -
  E3S96_RS04355 (E3S96_04355) sdhB 877428..878243 (-) 816 WP_000132057.1 succinate dehydrogenase iron-sulfur subunit -
  E3S96_RS04360 (E3S96_04360) sdhA 878243..880009 (-) 1767 WP_000818278.1 succinate dehydrogenase flavoprotein subunit -
  E3S96_RS04365 (E3S96_04365) - 880061..880675 (-) 615 WP_000079317.1 succinate dehydrogenase cytochrome b558 subunit -
  E3S96_RS04370 (E3S96_04370) uvrC 880999..882780 (-) 1782 WP_160190551.1 excinuclease ABC subunit UvrC Machinery gene
  E3S96_RS04375 (E3S96_04375) - 882971..883042 (+) 72 WP_223200532.1 hypothetical protein -
  E3S96_RS04380 (E3S96_04380) trxA 883105..883419 (-) 315 WP_001018928.1 thioredoxin -
  E3S96_RS04385 (E3S96_04385) mutS/mutS2 883592..885940 (-) 2349 WP_001249279.1 endonuclease MutS2 Machinery gene
  E3S96_RS04390 (E3S96_04390) polX 885950..887662 (-) 1713 WP_000161953.1 DNA polymerase/3'-5' exonuclease PolX -

Sequence

Protein


Download         Length: 593 a.a.        Molecular weight: 68669.34 Da        Isoelectric Point: 9.7443

>NTDB_id=364435 E3S96_RS04370 WP_160190551.1 880999..882780(-) (uvrC) [Staphylococcus aureus strain UP_1073]
MEDYKQRIKNKLNVVPMEPGCYLMKDRNDQVIYVGKAKKLRNRLRSYFTGAHDAKTTRLVGEIRHFEFIVTSSETESLLL
ELNLIKQYQPRYNILLKDDKSYPFIKITKEKYPRLLVTRTVKQGTGKYFGPYPNAYSAQETKKLLDRIYPYRKCDKMPDK
LCLYYHIGQCLGPCVYDVDLSKYAQMTKEITDFLNGEDKTILKSLEERMLTASESLDFERAKEYRDLIQHIQNLTNKQKI
MSSDKTIRDVFGYSVDKGWMCIQVFFIRQGNMIKRDTTMIPLQQTEEEEFYTFIGQFYSLNQHILPKEVHVPRNLDKEMI
QSVVDTKIVQPARGPKKEMVDLAAHNAKVSLNNKFELISRDESRTIKAIEELGTQMGIQTPIRIESFDNSNIQGVDPVSA
MVTFIDGKPDKKNYRKYKIKTVKGPDDYKSMREVVRRRYSRVLNEGLPLPDLIIVDGGKGHMNGVIDVLQNELGLDIPVA
GLQKNDKHQTSELLYGASAEIVPLKKNSQAFYLLHRIQDEVHRFAITFHRQTRQKTGLKSILDDIDGIGSKRKTLLLRSF
GSIKKMKEATLEDFKNLGIPENVAKNLHEQLHK

Nucleotide


Download         Length: 1782 bp        

>NTDB_id=364435 E3S96_RS04370 WP_160190551.1 880999..882780(-) (uvrC) [Staphylococcus aureus strain UP_1073]
TTGGAAGATTATAAACAACGAATTAAAAATAAATTAAATGTTGTACCTATGGAACCGGGTTGCTATTTAATGAAAGACCG
CAATGATCAAGTGATATATGTTGGGAAAGCTAAAAAATTAAGAAATCGATTACGATCATATTTTACGGGCGCACACGATG
CTAAAACAACGAGACTTGTTGGAGAAATACGGCATTTTGAATTTATTGTCACATCTAGTGAAACAGAGTCATTATTACTT
GAATTAAATTTGATCAAACAATATCAACCTAGATACAACATTTTATTAAAAGATGATAAAAGTTATCCATTTATTAAAAT
AACAAAGGAAAAATATCCTAGACTACTAGTGACGAGAACTGTAAAACAAGGTACTGGCAAATATTTCGGACCGTATCCGA
ATGCATATTCTGCTCAAGAAACTAAAAAGTTATTAGACAGAATATATCCATATCGCAAATGTGATAAGATGCCAGATAAA
TTATGTCTTTATTACCATATTGGACAATGTTTAGGACCATGTGTATATGACGTTGATTTGAGTAAATACGCACAAATGAC
GAAGGAAATTACTGATTTTCTGAATGGGGAAGACAAAACAATTTTAAAAAGTTTAGAAGAGCGAATGTTAACTGCAAGTG
AATCACTTGATTTTGAACGGGCTAAAGAATATAGAGATTTAATTCAACATATTCAAAATCTAACTAATAAACAAAAAATT
ATGTCATCAGATAAAACGATTCGTGATGTCTTTGGTTATAGTGTTGATAAAGGCTGGATGTGTATCCAAGTTTTCTTTAT
ACGACAAGGTAATATGATAAAACGAGATACAACGATGATTCCATTACAGCAAACAGAAGAAGAAGAATTTTATACATTTA
TTGGACAATTTTATAGCTTAAACCAACATATTTTACCTAAGGAAGTTCATGTGCCGCGTAATTTGGATAAAGAAATGATT
CAATCTGTTGTGGACACTAAAATCGTTCAACCCGCGCGAGGTCCCAAAAAAGAGATGGTTGACCTAGCTGCACATAACGC
TAAAGTATCCTTAAATAATAAATTTGAATTAATATCACGTGATGAGTCCAGAACAATTAAAGCAATTGAAGAACTTGGAA
CACAAATGGGAATTCAAACACCAATTAGAATTGAATCATTCGATAATTCTAATATTCAAGGTGTGGATCCAGTGTCAGCA
ATGGTTACATTTATCGACGGTAAACCAGACAAGAAAAATTATAGAAAGTATAAAATCAAAACGGTTAAAGGTCCAGATGA
TTACAAATCAATGAGAGAAGTAGTAAGACGCCGATATTCTCGCGTTTTAAACGAAGGATTACCATTACCTGATTTAATAA
TAGTAGATGGTGGTAAAGGACATATGAACGGGGTTATTGATGTGCTACAAAACGAATTAGGTCTTGATATCCCTGTTGCA
GGTTTGCAGAAAAATGATAAACACCAAACATCTGAATTATTATATGGCGCTAGTGCAGAAATTGTACCACTGAAGAAAAA
TAGCCAAGCATTTTATTTGTTGCACCGTATCCAAGATGAGGTTCACAGATTCGCAATCACCTTTCATAGACAAACACGTC
AAAAGACCGGCTTGAAATCAATACTTGATGATATAGATGGTATCGGTAGCAAACGTAAAACATTATTATTGCGTTCATTC
GGTTCAATCAAGAAAATGAAGGAAGCTACACTTGAAGATTTTAAAAATTTAGGTATTCCTGAAAACGTTGCAAAGAACCT
ACATGAACAATTGCATAAATAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(200-233)

GIY-YIG catalytic domain (GIY-YIG)

(19-93)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(379-526)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae R6

57.436

98.651

0.567
  uvrC Streptococcus pneumoniae TIGR4

57.436

98.651

0.567
  uvrC Streptococcus pneumoniae D39

57.436

98.651

0.567