Detailed information NTG0036383

Bioinformatically predicted

Overview

• Name: letS
• Type: Regulator
• Locus tag: LLO_RS06315
• Genome accession: NC_013861
• Coordinates: 1459946..1462678 (-)
• Length: 910 a.a.
• NCBI ID: WP_012979015.1
• Uniprot ID: -
• Organism: Legionella longbeachae NSW150
• Function: regulate competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1454946..1467678

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLO_RS06290 (llo1230)	-	1455089..1455625 (+)	537	Protein_1240	IS5 family transposase	-
LLO_RS06295 (llo1231)	-	1455798..1457198 (-)	1401	WP_003632056.1	APC family permease	-
LLO_RS06300 (llo1232)	-	1457529..1457852 (-)	324	WP_003632054.1	BolA family protein	-
LLO_RS06305 (llo1233)	pilA2	1457934..1458368 (-)	435	WP_003632053.1	pilin	Machinery gene
LLO_RS06310 (llo1234)	-	1458661..1459905 (-)	1245	WP_003632052.1	6-phosphofructokinase	-
LLO_RS06315 (llo1235)	letS	1459946..1462678 (-)	2733	WP_012979015.1	two-component system sensor histidine kinase LetS	Regulator
LLO_RS06320 (llo1236)	gltX	1462810..1464225 (+)	1416	WP_003632050.1	glutamate--tRNA ligase	-
LLO_RS06325 (llo1237)	-	1464222..1465496 (+)	1275	WP_003632048.1	serine hydrolase domain-containing protein	-
LLO_RS06330 (llo1238)	-	1465636..1466619 (+)	984	WP_003632046.1	hypothetical protein	-
LLO_RS06335 (llo1239)	gstA	1466678..1467280 (+)	603	WP_003632045.1	glutathione transferase GstA	-

Sequence

Protein

• Length: 910 a.a.
• Molecular weight: 102712.32 Da
• Isoelectric Point: 7.7707

>NTDB_id=36383 LLO_RS06315 WP_012979015.1 1459946..1462678(-) (letS) [Legionella longbeachae NSW150]
MKSIGIKYQLRITTLIPVFLVALLLAIFYNGLFGNDLKQHMSRLGEAYIRQLLPAAQYAMLRGDDRTLQGLINASTINPE
VKALAFYSSDGQLLAYRGGKHSLNKPFTAPKFTGDYIKSKQINPFTINFIAPVTIPKFNLYSNSSFKNILSPMASRADDI
LGWLSLDIDTRSMIIKRYQMLIVTIFITLFGLLVGLTIHYFLSKQIYLPISRLRRSMKQILRNEFETEIKTTSSGELGII
EQGCSHLQKKHLETIRDLNHHIEVATADLQQSLELLEEKNIELSLEKKKIEEKSRQKSEFIANMSHEIRTPMNGVIGFTN
VLLESKLDPLQLDYVKTIKSSAQDLLGIINDILDFSKIDAGKLHLDCIPLNIRHCIDEVLALAAPNAHKKGIDLIPITEL
NVPKIVLGDPFRVKQFISNLVTNAVKFTDHGYVLIRTNVEQETEKDYTLCITITDTGLGISPEDQSKLFTAFNQADTSIT
RRYGGSGLGLVICKKLCEEMKGRITFASELNKGSVFTAYIKVEKLVAYEVERNQVHPFAHFKMLCFDDNPMQLEALCNGL
GYWGIKCIAVSSLNQLAKELKDNKDCQIAFLNINKGYEQQITKLIAEHNYFPYVLISKWLINDYAALGAQGFLYKPISIQ
KLQDIIESLTNQENIEKSVNHELEGLREQLRFLHPDLLIAEDNPVNKMLLDSLLGTRSNITSVDNGEIAVSVCNEKKFSL
ILLDLRMPKINGLEAARLIRQKSEFNRHTPIVLISANGRDVNDIDLKKAGVNFCLQKPIDEKQLLIQILRIADKAKHSAI
DWQLCIQKASGNQSLAEEFLARFVEELLKNREEFIQLMHEKNVKQLGEVAHKLHGACCFSGVPTLQKKVVQVEKLAAHAA
SIEELAMPFAELIQSIDAVISEYENQKIKT

Nucleotide

• Length: 2733 bp

>NTDB_id=36383 LLO_RS06315 WP_012979015.1 1459946..1462678(-) (letS) [Legionella longbeachae NSW150]
TTGAAAAGCATTGGTATAAAGTATCAACTACGAATTACTACTTTAATTCCTGTTTTTCTCGTCGCCCTACTCCTTGCCAT
TTTTTATAATGGGTTGTTTGGTAATGACTTAAAACAACACATGTCTCGCCTTGGTGAAGCATATATCCGGCAATTACTTC
CGGCTGCCCAGTATGCTATGCTGCGTGGGGACGATCGAACCTTACAAGGCCTAATCAATGCCTCTACAATCAACCCCGAA
GTTAAAGCACTTGCTTTTTATAGTAGCGACGGTCAACTCCTTGCTTATCGTGGTGGCAAACATTCGCTTAACAAACCATT
TACTGCACCTAAATTCACCGGGGATTACATCAAAAGTAAACAAATTAACCCCTTTACTATTAATTTTATCGCGCCGGTTA
CGATTCCAAAATTCAATTTGTATTCCAATTCTTCTTTTAAAAATATTTTAAGTCCCATGGCATCCCGTGCTGATGACATT
CTTGGGTGGTTGTCTCTTGATATTGATACTCGTTCAATGATAATCAAACGTTATCAGATGCTTATTGTCACTATTTTCAT
TACTTTATTTGGGTTATTAGTAGGATTAACCATTCACTACTTTCTCTCCAAACAAATTTATTTACCTATTTCTCGTTTAC
GACGAAGCATGAAACAAATTTTGCGTAACGAGTTTGAAACAGAAATAAAAACAACAAGCTCTGGTGAATTAGGCATAATT
GAACAGGGATGTTCCCATTTGCAAAAAAAACACCTTGAAACGATACGTGATCTAAACCACCACATTGAGGTAGCCACGGC
TGATTTACAACAAAGTTTGGAACTCTTGGAAGAAAAAAATATTGAACTCTCCCTCGAAAAGAAAAAAATTGAAGAAAAAA
GTCGGCAAAAATCTGAGTTCATAGCCAATATGAGCCATGAAATTCGTACGCCGATGAATGGAGTTATTGGTTTTACTAAC
GTTTTGCTTGAAAGTAAACTCGATCCATTACAACTGGATTATGTAAAAACAATTAAATCATCAGCACAAGACTTATTAGG
GATTATCAATGATATTCTCGATTTCTCAAAAATTGATGCAGGAAAACTTCATCTCGATTGTATTCCGTTAAATATTCGCC
ATTGTATTGATGAAGTACTCGCTCTTGCAGCACCTAATGCCCATAAGAAGGGAATCGACTTAATTCCTATAACAGAACTA
AACGTACCTAAAATTGTTTTAGGGGATCCCTTCAGGGTGAAACAATTCATTAGCAACCTGGTAACTAATGCTGTTAAATT
TACCGATCATGGATATGTATTAATCCGTACCAATGTGGAGCAGGAAACGGAAAAAGATTACACTTTATGCATTACAATTA
CTGATACAGGCCTAGGTATTTCTCCTGAAGACCAAAGCAAATTATTTACAGCCTTCAATCAAGCAGATACAAGTATTACC
CGTCGTTATGGGGGCTCCGGACTTGGCTTGGTAATTTGCAAAAAACTCTGCGAGGAAATGAAAGGCCGTATTACTTTCGC
CAGCGAACTCAACAAAGGTTCTGTATTTACCGCTTATATCAAGGTTGAAAAATTGGTTGCTTATGAAGTTGAAAGAAATC
AAGTGCATCCTTTTGCGCATTTCAAAATGCTTTGTTTTGACGATAACCCAATGCAATTGGAAGCCCTGTGTAATGGCTTA
GGATATTGGGGAATAAAATGTATCGCTGTAAGTTCACTCAATCAACTCGCGAAAGAGCTGAAAGACAATAAAGACTGCCA
AATCGCATTTCTTAATATCAATAAAGGCTACGAACAGCAAATTACCAAGCTAATAGCCGAACATAATTATTTTCCCTATG
TATTAATCTCTAAATGGCTTATCAATGATTATGCAGCACTTGGAGCACAGGGATTTTTATATAAACCCATTAGCATCCAA
AAACTCCAAGATATTATTGAGTCATTAACAAATCAGGAAAATATTGAAAAGTCGGTTAACCATGAATTAGAAGGTTTAAG
GGAACAATTACGTTTCTTACATCCTGATCTTCTTATAGCTGAAGATAATCCAGTAAATAAAATGCTTCTTGATTCTTTAT
TAGGGACTCGTTCCAACATTACATCCGTTGATAATGGCGAAATAGCCGTATCGGTGTGTAATGAAAAGAAATTCAGTCTC
ATCTTGCTTGATTTGCGTATGCCTAAAATAAATGGCTTGGAAGCTGCTCGACTTATCCGCCAAAAATCAGAGTTTAATCG
TCATACACCAATAGTATTGATTAGTGCAAATGGTAGAGATGTTAATGATATTGATTTAAAGAAAGCTGGTGTAAATTTTT
GTTTGCAAAAGCCTATAGACGAAAAACAATTATTAATTCAAATTTTACGTATTGCAGATAAAGCAAAACACTCAGCAATA
GATTGGCAACTATGTATTCAAAAAGCCTCAGGAAATCAATCACTTGCTGAAGAGTTTCTTGCTCGGTTTGTAGAAGAATT
GCTTAAAAATCGTGAAGAGTTTATCCAATTAATGCATGAAAAAAATGTGAAGCAACTGGGCGAAGTGGCGCATAAACTTC
ATGGAGCATGTTGTTTTAGTGGTGTTCCCACGTTACAAAAAAAAGTAGTTCAGGTTGAAAAACTTGCTGCGCATGCTGCT
TCAATCGAAGAGTTAGCTATGCCTTTCGCAGAATTAATTCAAAGCATCGATGCGGTGATTAGTGAATACGAAAATCAAAA
AATAAAAACTTAG

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (408-523)

• His Kinase A (phospho-acceptor) domain (HisKA) (297-361)

• Single cache domain 4 (sCache_4) (35-179)

• Hpt domain (Hpt) (818-899)

• Response regulator receiver domain (Response_reg) (678-786)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
letS	Legionella pneumophila strain ERS1305867	77.925	99.56	0.776