Detailed information NTG0363510

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: EQO03_RS09075
• Genome accession: NZ_CP040344
• Coordinates: 1726625..1729060 (+)
• Length: 811 a.a.
• NCBI ID: WP_000971179.1
• Uniprot ID: A0A063CE58
• Organism: Bacillus albus strain DLOU-Yingkou
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1721625..1734060

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQO03_RS09060	ctsR	1724350..1724811 (+)	462	WP_048526354.1	transcriptional regulator CtsR	-
EQO03_RS09065	-	1724985..1725533 (+)	549	WP_048526355.1	UvrB/UvrC motif-containing protein	-
EQO03_RS09070	-	1725538..1726602 (+)	1065	WP_048526356.1	protein arginine kinase	-
EQO03_RS09075	clpC	1726625..1729060 (+)	2436	WP_000971179.1	ATP-dependent protease ATP-binding subunit ClpC	Regulator
EQO03_RS09080	radA	1729157..1730533 (+)	1377	WP_157409255.1	DNA repair protein RadA	Machinery gene
EQO03_RS09085	disA	1730537..1731610 (+)	1074	WP_048526357.1	DNA integrity scanning diadenylate cyclase DisA	-
EQO03_RS09090	-	1731771..1732880 (+)	1110	WP_048526358.1	PIN/TRAM domain-containing protein	-
EQO03_RS09095	ispD	1732897..1733577 (+)	681	WP_071757382.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-

Sequence

Protein

• Length: 811 a.a.
• Molecular weight: 90530.34 Da
• Isoelectric Point: 6.4056

>NTDB_id=363510 EQO03_RS09075 WP_000971179.1 1726625..1729060(+) (clpC) [Bacillus albus strain DLOU-Yingkou]
MMFGRFTERAQKVLALSQEEAIRIGHNNIGTEHILLGLVREGEGIAAKALIALGLSPEKVQKEVEALIGRGTEASQTVHY
TPRAKKVIELSMDEARKLGHSYVGTEHILLGLIREGEGVAARVLNNLGVSLNKARQQVLQLLGSNEASSGHQGGSSTNAN
TPTLDSLARDLTVVARENRLDPVIGRGKEIQRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQQIVNNEVPETLRDKRV
MTLDMGTVVAGTKYRGEFEDRLKKVMDEIRQAGNIILFIDELHTLIGAGGAEGAIDASNILKPSLARGELQCIGATTLDE
YRKYIEKDAALERRFQPIHVDEPSLDESTQILKGLRDRYEAHHRVSITDDAIDAAVKLSDRYITDRFLPDKAIDLIDEAA
SKVRLRSYTTPPNLKELEVKLEEIRKEKDAAVQSQEFEKAASLRDMEQRLREKLEDTKRQWKEQQGKENSEVTVEDIANV
VSTWTRIPVSKLAQTETDKLLNLESILHDRVIGQDEAVVAVAKAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALA
ESMFGDEDAMIRIDMSEYMEKHSTSRLVGSPPGYVGYEEGGQLTEKVRRKPYSVVLLDEVEKAHPDVFNILLQVLEDGRL
TDSKGRTVDFRNTIVIMTSNVGAEALKRNKHLGFNVQDESRDYSDMKGKVMDELKKAFRPEFLNRIDEIIVFHMLEKKHI
QEIVTLMVNQLVNRLKEQEIELHLTEGAISAIADKGFDREYGARPLRRAIQKHVEDRLSEELLKGAIEKGQKVIFDVEGE
SFVIHSAEKVK

Nucleotide

• Length: 2436 bp

>NTDB_id=363510 EQO03_RS09075 WP_000971179.1 1726625..1729060(+) (clpC) [Bacillus albus strain DLOU-Yingkou]
ATGATGTTTGGAAGATTTACAGAAAGAGCACAGAAAGTATTAGCTTTATCTCAAGAGGAAGCAATTCGCATTGGGCATAA
TAATATTGGAACAGAACATATTTTACTTGGGCTTGTACGCGAAGGTGAAGGAATTGCAGCAAAAGCGTTAATTGCTCTTG
GATTAAGTCCAGAGAAAGTTCAAAAAGAGGTAGAAGCGTTAATTGGACGCGGAACAGAAGCTTCTCAAACTGTACATTAT
ACACCGCGTGCTAAAAAGGTTATTGAGTTGTCGATGGATGAAGCTCGTAAGTTAGGTCATTCTTACGTTGGAACAGAACA
TATCCTACTCGGTTTAATCCGTGAGGGTGAAGGTGTAGCAGCACGAGTTTTAAATAACTTAGGTGTTAGCCTAAATAAGG
CAAGACAACAAGTATTGCAACTGCTTGGAAGTAATGAAGCAAGTTCAGGTCACCAAGGTGGTTCTTCAACAAATGCAAAT
ACACCAACACTTGATAGTTTAGCGCGTGATTTAACGGTTGTTGCACGTGAAAATCGTTTAGATCCTGTTATTGGGCGTGG
TAAAGAAATTCAACGTGTAATTGAAGTTTTAAGCCGTAGAACAAAAAATAATCCCGTGTTAATTGGAGAGCCTGGTGTAG
GTAAAACGGCAATCGCAGAAGGATTAGCACAACAAATCGTAAATAATGAAGTTCCTGAAACTTTAAGAGATAAGCGCGTT
ATGACACTAGATATGGGTACAGTGGTAGCTGGAACGAAATATCGTGGTGAATTTGAAGATCGTTTGAAGAAAGTAATGGA
TGAAATTCGTCAAGCGGGAAATATCATTCTATTTATTGATGAACTTCATACATTAATTGGTGCAGGTGGAGCAGAAGGTG
CTATTGATGCATCGAACATTTTAAAACCATCTTTAGCACGCGGAGAGTTACAATGTATTGGGGCGACAACGTTAGACGAA
TATCGCAAATATATTGAAAAAGACGCGGCTTTAGAGAGACGTTTCCAACCAATTCACGTTGATGAGCCAAGTTTAGATGA
ATCAACTCAAATCTTGAAAGGTTTACGTGATCGTTATGAGGCGCATCACCGCGTGTCTATTACAGATGATGCAATTGATG
CAGCTGTAAAGCTTTCAGATCGTTATATTACAGATCGTTTCTTACCAGATAAAGCAATTGATTTAATTGATGAAGCTGCT
TCAAAGGTTCGTTTACGCTCTTATACAACACCACCAAATCTAAAAGAGCTTGAAGTGAAGCTTGAGGAAATTAGAAAAGA
AAAAGATGCAGCTGTACAAAGTCAAGAATTTGAAAAAGCTGCTTCCTTACGTGATATGGAACAACGCTTACGTGAGAAGT
TAGAAGATACGAAGCGTCAATGGAAAGAGCAACAAGGAAAAGAAAATTCAGAAGTGACAGTAGAAGATATTGCAAATGTC
GTTTCTACGTGGACTCGTATTCCGGTTTCTAAGCTTGCACAAACAGAGACTGATAAATTATTAAACTTAGAATCGATTCT
TCACGATCGTGTTATTGGTCAAGATGAAGCGGTAGTAGCTGTAGCGAAAGCTGTTCGTCGTGCTAGAGCAGGATTGAAAG
ATCCGAAGCGTCCGATTGGTTCGTTTATTTTCTTAGGACCAACAGGTGTAGGTAAAACAGAGCTAGCAAGAGCTTTAGCA
GAATCTATGTTCGGTGATGAGGATGCAATGATTCGCATCGATATGTCTGAGTACATGGAGAAGCATTCTACTTCTCGTTT
AGTTGGATCTCCTCCAGGATATGTTGGATATGAAGAAGGTGGACAATTAACAGAAAAGGTTCGCCGTAAGCCATATTCAG
TTGTCTTATTAGATGAAGTAGAGAAAGCTCATCCTGATGTGTTTAACATTTTACTACAAGTATTAGAAGATGGTCGCTTA
ACAGATTCTAAAGGGCGTACAGTTGATTTCCGTAATACAATTGTTATTATGACATCTAACGTTGGTGCAGAGGCGTTAAA
ACGTAATAAACATCTTGGATTTAACGTACAAGATGAGAGCCGCGATTATTCAGATATGAAAGGTAAAGTAATGGATGAAC
TGAAAAAGGCATTTCGTCCAGAGTTCTTAAACCGTATTGATGAAATTATCGTGTTCCATATGCTTGAGAAAAAACATATT
CAAGAGATTGTAACACTTATGGTAAATCAGTTAGTGAACCGCTTAAAAGAGCAAGAAATTGAATTGCATTTAACTGAAGG
AGCAATTTCAGCTATTGCTGATAAAGGATTCGACCGAGAGTATGGTGCTCGCCCGCTTCGTAGAGCAATTCAGAAGCATG
TAGAAGATAGACTATCGGAAGAGCTTTTAAAAGGTGCTATTGAGAAAGGACAAAAAGTTATCTTTGATGTTGAAGGAGAA
TCATTTGTCATTCATAGTGCTGAAAAGGTAAAATAA

Domains

Predicted by InterproScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (18-69)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (93-143)

• AAA domain (Cdc48 subfamily) (AAA_2) (537-709)

• ATPase family associated with various cellular activities (AAA) (AAA) (206-318)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (715-793)

• AAA lid domain (AAA_lid_9) (345-446)

3D structure

• AlphaFold DB: A0A063CE58

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	85.926	99.877	0.858
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	50.5	98.644	0.498
clpC	Streptococcus thermophilus LMD-9	45.969	100	0.471
clpC	Streptococcus mutans UA159	44.881	100	0.465
clpC	Streptococcus thermophilus LMG 18311	45.476	100	0.465
clpC	Streptococcus pneumoniae D39	46.675	98.274	0.459
clpC	Streptococcus pneumoniae Rx1	46.675	98.274	0.459
clpC	Streptococcus pneumoniae TIGR4	46.375	98.644	0.457
clpE	Streptococcus mutans UA159	53.538	80.148	0.429
clpE	Streptococcus pneumoniae R6	52.705	79.778	0.42
clpE	Streptococcus pneumoniae TIGR4	52.705	79.778	0.42
clpE	Streptococcus pneumoniae Rx1	52.705	79.778	0.42
clpE	Streptococcus pneumoniae D39	52.705	79.778	0.42
clpC	Lactococcus lactis subsp. cremoris KW2	51.893	78.175	0.406