Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   E3S73_RS02075 Genome accession   NZ_CP047799
Coordinates   366457..367719 (+) Length   420 a.a.
NCBI ID   WP_000472293.1    Uniprot ID   Q6GG31
Organism   Staphylococcus aureus strain UP_322     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 361457..372719
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3S73_RS02040 (E3S73_02040) infC 361985..362512 (+) 528 WP_001791219.1 translation initiation factor IF-3 -
  E3S73_RS02045 (E3S73_02045) rpmI 362541..362741 (+) 201 WP_001125540.1 50S ribosomal protein L35 -
  E3S73_RS02050 (E3S73_02050) rplT 362788..363144 (+) 357 WP_001138360.1 50S ribosomal protein L20 -
  E3S73_RS02055 (E3S73_02055) - 363286..363894 (+) 609 WP_000032653.1 NUDIX domain-containing protein -
  E3S73_RS02060 (E3S73_02060) - 363913..364842 (+) 930 WP_001280016.1 hypothetical protein -
  E3S73_RS02065 (E3S73_02065) - 364847..364957 (+) 111 WP_001790560.1 hypothetical protein -
  E3S73_RS02070 (E3S73_02070) tig 365005..366306 (+) 1302 WP_000127572.1 trigger factor -
  E3S73_RS02075 (E3S73_02075) clpX 366457..367719 (+) 1263 WP_000472293.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  E3S73_RS02080 (E3S73_02080) yihA 367873..368463 (+) 591 WP_000867694.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  E3S73_RS02085 (E3S73_02085) hemA 368680..370026 (+) 1347 WP_000545456.1 glutamyl-tRNA reductase -
  E3S73_RS02090 (E3S73_02090) ccsA 370048..370863 (+) 816 WP_001157326.1 cytochrome c biogenesis protein -
  E3S73_RS02095 (E3S73_02095) hemC 370905..371831 (+) 927 WP_001230225.1 hydroxymethylbilane synthase -
  E3S73_RS02100 (E3S73_02100) - 371853..372521 (+) 669 WP_000805946.1 uroporphyrinogen-III synthase -

Sequence

Protein


Download         Length: 420 a.a.        Molecular weight: 46279.44 Da        Isoelectric Point: 4.2645

>NTDB_id=362977 E3S73_RS02075 WP_000472293.1 366457..367719(+) (clpX) [Staphylococcus aureus strain UP_322]
MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAITELPTPKEIMDHLNEYVIGQEK
AKKSLAVAVYNHYKRIQQLGPKEDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENIL
LRLIQAADFDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTN
ILFILGGAFDGIEEVIKRRLGEKVIGFSSNEADKYDEQALLAQIRPEDLQAYGLIPEFIGRVPIVANLETLDVTALKNIL
TQPKNALVKQYTKMLELDDVDLEFTEEALSAISEKAIERKTGARGLRSIIEESLIDIMFDVPSNENVTKVVITAQTINEE
TEPELYDAEGNLINNSKTSA

Nucleotide


Download         Length: 1263 bp        

>NTDB_id=362977 E3S73_RS02075 WP_000472293.1 366457..367719(+) (clpX) [Staphylococcus aureus strain UP_322]
ATGTTTAAATTCAATGAAGATGAAGAAAATTTGAAATGCTCTTTCTGCGGAAAAGACCAAGATCAAGTAAAAAAACTTGT
AGCAGGAAGTGGTGTATATATTTGTAATGAGTGTATTGAATTATGCTCAGAAATCGTCGAAGAAGAATTAGCTCAAAACA
CTTCTGAAGCGATTACAGAATTACCTACTCCTAAAGAAATTATGGATCATTTAAACGAATATGTTATTGGTCAAGAAAAA
GCTAAAAAATCTTTAGCTGTGGCTGTTTATAACCACTATAAGCGTATTCAACAATTAGGACCAAAAGAAGATGATGTTGA
GTTACAAAAAAGTAACATTGCCTTAATTGGGCCAACAGGTAGTGGTAAAACATTATTAGCTCAAACATTAGCCAAGACGT
TGAATGTACCATTTGCAATTGCAGATGCGACAAGTTTAACTGAAGCTGGTTATGTAGGCGATGATGTTGAAAATATCTTG
TTGAGATTAATTCAAGCAGCTGACTTTGACATTGATAAAGCCGAAAAAGGTATTATTTATGTAGATGAAATTGATAAAAT
TGCACGTAAATCTGAAAACACATCTATAACACGTGACGTTTCAGGTGAAGGTGTTCAACAAGCATTGCTTAAAATCTTAG
AAGGTACAACTGCAAGTGTTCCGCCACAAGGTGGACGCAAACATCCAAACCAAGAAATGATTCAAATTGATACAACAAAT
ATCTTATTTATTCTTGGTGGTGCCTTTGATGGTATTGAAGAAGTGATTAAGCGCCGTCTTGGTGAAAAAGTTATTGGTTT
CTCAAGCAATGAAGCTGATAAATATGACGAACAAGCATTATTAGCACAAATTCGCCCAGAAGATTTGCAAGCCTATGGTT
TGATTCCTGAATTTATCGGACGTGTGCCAATTGTAGCTAATTTAGAAACATTAGATGTAACTGCGTTGAAAAACATCTTA
ACGCAACCTAAAAATGCACTTGTGAAACAATATACTAAAATGCTGGAATTAGATGATGTAGATTTAGAGTTCACTGAAGA
AGCTTTATCAGCAATTAGTGAAAAAGCAATTGAAAGAAAAACAGGTGCGCGTGGTTTACGTTCAATCATAGAAGAATCGT
TAATCGATATTATGTTTGATGTGCCTTCTAACGAAAATGTAACGAAGGTAGTTATTACAGCACAAACAATTAATGAAGAA
ACTGAACCAGAATTATACGACGCAGAAGGTAATTTAATTAATAATAGTAAAACATCAGCTTAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-305)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q6GG31

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

66.917

95

0.636
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.456

94.048

0.531