Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   E3S75_RS04380 Genome accession   NZ_CP047798
Coordinates   882082..883863 (-) Length   593 a.a.
NCBI ID   WP_000390521.1    Uniprot ID   -
Organism   Staphylococcus aureus strain UP_378     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 877082..888863
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3S75_RS04360 (E3S75_04360) racE 877471..878271 (-) 801 WP_001039660.1 glutamate racemase -
  E3S75_RS04365 (E3S75_04365) sdhB 878511..879326 (-) 816 WP_000132057.1 succinate dehydrogenase iron-sulfur subunit -
  E3S75_RS04370 (E3S75_04370) sdhA 879326..881092 (-) 1767 WP_000818278.1 succinate dehydrogenase flavoprotein subunit -
  E3S75_RS04375 (E3S75_04375) - 881144..881758 (-) 615 WP_149679774.1 succinate dehydrogenase cytochrome b558 subunit -
  E3S75_RS04380 (E3S75_04380) uvrC 882082..883863 (-) 1782 WP_000390521.1 excinuclease ABC subunit UvrC Machinery gene
  E3S75_RS04385 (E3S75_04385) - 884054..884125 (+) 72 WP_223200532.1 hypothetical protein -
  E3S75_RS04390 (E3S75_04390) trxA 884188..884502 (-) 315 WP_001018928.1 thioredoxin -
  E3S75_RS04395 (E3S75_04395) mutS/mutS2 884675..887023 (-) 2349 WP_160195120.1 endonuclease MutS2 Machinery gene
  E3S75_RS04400 (E3S75_04400) polX 887033..888744 (-) 1712 Protein_840 DNA polymerase/3'-5' exonuclease PolX -

Sequence

Protein


Download         Length: 593 a.a.        Molecular weight: 68653.34 Da        Isoelectric Point: 9.7443

>NTDB_id=362918 E3S75_RS04380 WP_000390521.1 882082..883863(-) (uvrC) [Staphylococcus aureus strain UP_378]
MEDYKQRIKNKLNVVPMEPGCYLMKDRNDQVIYVGKAKKLRNRLRSYFTGAHDAKTTRLVGEIRHFEFIVTSSETESLLL
ELNLIKQYQPRYNILLKDDKSYPFIKITKEKYPRLLVTRTVKQGTGKYFGPYPNAYSAQETKKLLDRIYPYRKCDKMPDK
LCLYYHIGQCLGPCVYDVDLSKYAQMTKEITDFLNGEDKTILKSLEERMLTASESLDFERAKEYRDLIQHIQNLTNKQKI
MSSDKTIRDVFGYSVDKGWMCIQVFFIRQGNMIKRDTTMIPLQQTEEEEFYTFIGQFYSLNQHILPKEVHVPRNLDKEMI
QSVVDTKIVQPARGPKKEMVDLAAHNAKVSLNNKFELISRDESRTIKAIEELGTQMGIQTPIRIEAFDNSNIQGVDPVSA
MVTFIDGKPDKKNYRKYKIKTVKGPDDYKSMREVVRRRYSRVLNEGLPLPDLIIVDGGKGHMNGVIDVLQNELGLDIPVA
GLQKNDKHQTSELLYGASAEIVPLKKNSQAFYLLHRIQDEVHRFAITFHRQTRQKTGLKSILDDIDGIGSKRKTLLLRSF
GSIKKMKEATLEDFKNLGIPENVAKNLHEQLHK

Nucleotide


Download         Length: 1782 bp        

>NTDB_id=362918 E3S75_RS04380 WP_000390521.1 882082..883863(-) (uvrC) [Staphylococcus aureus strain UP_378]
TTGGAAGATTATAAACAACGAATTAAAAATAAATTAAATGTTGTACCTATGGAACCGGGTTGCTATTTAATGAAAGACCG
CAATGATCAAGTGATATATGTTGGGAAAGCTAAAAAATTAAGAAATCGATTACGATCATATTTTACGGGCGCACACGATG
CTAAAACAACGAGACTTGTTGGAGAAATACGGCATTTTGAATTTATTGTCACATCTAGTGAAACAGAGTCATTATTACTT
GAATTAAATTTGATCAAACAATATCAACCTAGATACAACATTTTATTAAAAGATGATAAAAGTTATCCATTTATTAAAAT
AACAAAGGAAAAATATCCTAGACTACTAGTGACGAGAACTGTAAAACAAGGTACTGGCAAATATTTCGGACCGTATCCGA
ATGCATATTCTGCTCAAGAAACTAAAAAGTTATTAGACAGAATATATCCATATCGCAAATGTGATAAGATGCCAGATAAA
TTATGTCTTTATTACCATATTGGACAATGTTTAGGACCATGTGTATATGACGTTGATTTGAGTAAATACGCACAAATGAC
GAAGGAAATTACTGATTTTCTGAATGGGGAAGACAAAACAATTTTAAAAAGTTTAGAAGAGCGAATGTTAACTGCAAGTG
AATCACTTGATTTTGAACGGGCTAAAGAATATAGAGATTTAATTCAACATATTCAAAATCTAACTAATAAACAAAAAATT
ATGTCATCAGATAAAACGATTCGTGATGTCTTTGGTTATAGTGTTGATAAAGGCTGGATGTGTATCCAAGTTTTCTTTAT
ACGACAAGGTAATATGATAAAACGAGATACAACGATGATTCCATTACAGCAAACAGAAGAAGAAGAATTTTATACATTTA
TTGGACAATTTTATAGCTTAAACCAACATATTTTACCTAAGGAAGTTCATGTGCCGCGTAATTTGGATAAAGAAATGATT
CAATCTGTTGTGGACACTAAAATCGTTCAACCCGCGCGAGGTCCCAAAAAAGAGATGGTTGACCTAGCTGCACATAACGC
TAAAGTATCCTTAAATAATAAATTTGAATTAATATCACGTGATGAGTCCAGAACAATTAAAGCAATTGAAGAACTTGGAA
CACAAATGGGAATTCAAACACCAATTAGAATTGAAGCATTCGATAATTCTAATATTCAAGGTGTGGATCCAGTGTCAGCA
ATGGTTACATTTATCGACGGTAAACCAGACAAGAAAAATTATAGAAAGTATAAAATCAAAACGGTTAAAGGTCCAGATGA
TTACAAATCAATGAGAGAAGTAGTAAGACGCCGATATTCTCGCGTTTTAAACGAAGGATTACCATTACCTGATTTAATAA
TAGTAGATGGTGGTAAAGGACATATGAACGGGGTTATTGATGTGCTACAAAACGAATTAGGTCTTGATATCCCTGTTGCA
GGTTTGCAGAAAAATGATAAACACCAAACATCTGAATTATTATATGGCGCTAGTGCAGAAATTGTACCACTGAAGAAAAA
TAGCCAAGCATTTTATTTGTTGCACCGTATCCAAGATGAGGTTCACAGATTCGCAATCACCTTTCATAGACAAACACGTC
AAAAGACCGGCTTGAAATCAATACTTGATGATATAGATGGTATCGGTAGCAAACGTAAAACATTATTATTGCGTTCATTC
GGTTCAATCAAGAAAATGAAGGAAGCTACACTTGAAGATTTTAAAAATTTAGGTATTCCTGAAAACGTTGCAAAGAACCT
ACATGAACAATTGCATAAATAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(200-233)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(379-526)

GIY-YIG catalytic domain (GIY-YIG)

(19-93)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae R6

57.265

98.651

0.565
  uvrC Streptococcus pneumoniae TIGR4

57.265

98.651

0.565
  uvrC Streptococcus pneumoniae D39

57.265

98.651

0.565

Multiple sequence alignment