Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   E3S75_RS01645 Genome accession   NZ_CP047798
Coordinates   304991..306253 (+) Length   420 a.a.
NCBI ID   WP_000472293.1    Uniprot ID   Q6GG31
Organism   Staphylococcus aureus strain UP_378     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 299991..311253
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3S75_RS01610 (E3S75_01610) infC 300519..301046 (+) 528 WP_001807711.1 translation initiation factor IF-3 -
  E3S75_RS01615 (E3S75_01615) rpmI 301075..301275 (+) 201 WP_001125540.1 50S ribosomal protein L35 -
  E3S75_RS01620 (E3S75_01620) rplT 301322..301678 (+) 357 WP_001138360.1 50S ribosomal protein L20 -
  E3S75_RS01625 (E3S75_01625) - 301820..302428 (+) 609 WP_000032657.1 NUDIX domain-containing protein -
  E3S75_RS01630 (E3S75_01630) - 302447..303376 (+) 930 WP_001280025.1 hypothetical protein -
  E3S75_RS01635 (E3S75_01635) - 303381..303491 (+) 111 WP_001790560.1 hypothetical protein -
  E3S75_RS01640 (E3S75_01640) tig 303539..304840 (+) 1302 WP_000127572.1 trigger factor -
  E3S75_RS01645 (E3S75_01645) clpX 304991..306253 (+) 1263 WP_000472293.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  E3S75_RS01650 (E3S75_01650) yihA 306407..306997 (+) 591 WP_000867697.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  E3S75_RS01655 (E3S75_01655) hemA 307214..308560 (+) 1347 WP_000545465.1 glutamyl-tRNA reductase -
  E3S75_RS01660 (E3S75_01660) ccsA 308582..309397 (+) 816 WP_001157329.1 cytochrome c biogenesis protein -
  E3S75_RS01665 (E3S75_01665) hemC 309439..310365 (+) 927 WP_001230218.1 hydroxymethylbilane synthase -
  E3S75_RS01670 (E3S75_01670) - 310387..311055 (+) 669 WP_000805953.1 uroporphyrinogen-III synthase -

Sequence

Protein


Download         Length: 420 a.a.        Molecular weight: 46279.44 Da        Isoelectric Point: 4.2645

>NTDB_id=362884 E3S75_RS01645 WP_000472293.1 304991..306253(+) (clpX) [Staphylococcus aureus strain UP_378]
MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAITELPTPKEIMDHLNEYVIGQEK
AKKSLAVAVYNHYKRIQQLGPKEDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENIL
LRLIQAADFDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTN
ILFILGGAFDGIEEVIKRRLGEKVIGFSSNEADKYDEQALLAQIRPEDLQAYGLIPEFIGRVPIVANLETLDVTALKNIL
TQPKNALVKQYTKMLELDDVDLEFTEEALSAISEKAIERKTGARGLRSIIEESLIDIMFDVPSNENVTKVVITAQTINEE
TEPELYDAEGNLINNSKTSA

Nucleotide


Download         Length: 1263 bp        

>NTDB_id=362884 E3S75_RS01645 WP_000472293.1 304991..306253(+) (clpX) [Staphylococcus aureus strain UP_378]
ATGTTTAAATTTAATGAAGATGAAGAAAATTTGAAATGCTCTTTCTGCGGAAAAGACCAAGATCAAGTAAAAAAACTTGT
AGCAGGAAGTGGTGTATATATTTGTAATGAGTGTATTGAATTATGCTCAGAAATCGTCGAAGAAGAATTAGCTCAAAACA
CTTCTGAAGCGATTACAGAATTACCTACTCCTAAAGAAATTATGGATCATTTAAACGAATATGTTATTGGTCAAGAAAAA
GCTAAAAAATCTTTAGCTGTGGCTGTTTATAACCACTATAAGCGTATTCAACAATTAGGACCAAAAGAAGATGATGTTGA
ATTACAAAAAAGTAACATTGCCTTAATTGGGCCAACAGGTAGTGGTAAAACATTATTAGCTCAAACATTAGCCAAGACGT
TGAATGTACCATTTGCAATTGCAGATGCGACAAGTTTAACTGAAGCTGGTTATGTAGGCGATGATGTTGAAAATATCTTG
TTGAGATTAATTCAAGCAGCTGACTTTGACATTGATAAAGCCGAAAAAGGTATTATTTATGTAGATGAAATTGATAAAAT
TGCACGTAAATCTGAAAACACATCTATAACACGTGACGTTTCAGGTGAAGGTGTTCAACAAGCATTGCTTAAAATCTTAG
AAGGTACAACTGCAAGTGTTCCACCACAAGGTGGACGCAAACATCCAAACCAAGAAATGATTCAAATTGATACAACAAAT
ATCTTATTTATTCTTGGTGGTGCCTTTGATGGTATTGAAGAAGTGATTAAGCGCCGCCTTGGTGAAAAAGTTATTGGTTT
CTCAAGCAATGAAGCTGATAAATATGATGAACAAGCATTATTAGCACAAATTCGCCCAGAAGATTTGCAAGCCTATGGTT
TGATTCCTGAATTTATCGGACGTGTGCCAATTGTAGCTAATTTAGAAACATTAGATGTAACTGCGTTGAAAAACATCTTA
ACTCAACCTAAAAATGCACTTGTGAAACAATATACTAAAATGCTGGAATTAGATGATGTGGATTTAGAGTTCACTGAAGA
AGCTTTATCAGCAATTAGTGAAAAAGCAATTGAAAGAAAAACAGGTGCGCGTGGTTTACGTTCAATCATAGAAGAATCGT
TAATCGATATTATGTTTGATGTGCCTTCTAACGAAAATGTAACGAAGGTAGTTATTACAGCACAAACAATTAATGAAGAA
ACTGAACCAGAACTATACGACGCAGAAGGTAATTTAATTAATAATAGTAAAACATCAGCTTAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-305)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q6GG31

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

66.917

95

0.636
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.456

94.048

0.531