Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   FD735_RS08125 Genome accession   NZ_CP040231
Coordinates   1549873..1550562 (-) Length   229 a.a.
NCBI ID   WP_070567257.1    Uniprot ID   A0A1E9G1L2
Organism   Streptococcus sp. 1643     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1544873..1555562
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FD735_RS08105 (FD735_08105) - 1545820..1546827 (-) 1008 WP_139658924.1 phosphomevalonate kinase -
  FD735_RS08110 (FD735_08110) mvaD 1546814..1547767 (-) 954 WP_139658925.1 diphosphomevalonate decarboxylase -
  FD735_RS08115 (FD735_08115) mvk 1547749..1548627 (-) 879 WP_139658926.1 mevalonate kinase -
  FD735_RS08120 (FD735_08120) cbpF 1548745..1549773 (-) 1029 WP_139658927.1 choline-binding protein CbpF -
  FD735_RS08125 (FD735_08125) covR 1549873..1550562 (-) 690 WP_070567257.1 response regulator transcription factor Regulator
  FD735_RS08130 (FD735_08130) gndA 1550574..1551998 (-) 1425 WP_061587344.1 NADP-dependent phosphogluconate dehydrogenase -
  FD735_RS08135 (FD735_08135) - 1552074..1553519 (-) 1446 WP_139658928.1 cell division site-positioning protein MapZ family protein -
  FD735_RS08140 (FD735_08140) - 1553532..1554689 (-) 1158 WP_139658929.1 class I SAM-dependent RNA methyltransferase -
  FD735_RS08150 (FD735_08150) gpsB 1555175..1555504 (-) 330 WP_033630347.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26784.96 Da        Isoelectric Point: 8.0259

>NTDB_id=362659 FD735_RS08125 WP_070567257.1 1549873..1550562(-) (covR) [Streptococcus sp. 1643]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNARLGDMTAQDFADKLSRTKPASVIMVL
DHREELQDQIETIQRFAVSYIYKPVIIDQLVARISAIFRGRDFIDQHCSQMKVPTSYRNLRMDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=362659 FD735_RS08125 WP_070567257.1 1549873..1550562(-) (covR) [Streptococcus sp. 1643]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTCGCTCATTTTCTCAGTCTGGAACTCCAAAAAGAGCAATA
CCGTGTTGATCTGGTTGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTCCAGACAGATTATGACTTGATTTTACTGAATG
CTCGTCTGGGGGATATGACGGCCCAGGATTTTGCAGACAAGCTGAGTCGGACAAAACCGGCCTCAGTGATCATGGTCTTA
GACCATCGCGAAGAATTGCAAGACCAGATTGAGACAATCCAGCGCTTCGCCGTTTCTTACATCTATAAGCCAGTGATTAT
TGATCAGCTGGTGGCTCGTATTTCAGCGATTTTCCGAGGTCGGGACTTTATCGACCAACACTGTAGTCAGATGAAGGTCC
CAACGTCTTATCGCAATTTGCGTATGGATGTAGAACATCATACCGTTTATCGTGGCGAGGAGATGATTGCTCTAACGCGC
CGTGAGTATGACCTTTTGGCCACTCTCATGGGAAGCAAGAAGGTCTTGACTCGTGAGCAGTTGTTGGAAAGTGTTTGGAA
GTACGAAAGTGCGACAGAAACCAATATCGTGGATGTTTATATCCGTTATCTACGTAGCAAGCTTGATGTAAAAGGTCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGATACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1E9G1L2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.696

100

0.489
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.491

99.563

0.463

Multiple sequence alignment