Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   FD735_RS01350 Genome accession   NZ_CP040231
Coordinates   233438..234262 (+) Length   274 a.a.
NCBI ID   WP_049505185.1    Uniprot ID   A0A1L8Q3D7
Organism   Streptococcus sp. 1643     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 228438..239262
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FD735_RS01315 (FD735_01315) asnA 228528..229520 (+) 993 WP_139658304.1 aspartate--ammonia ligase -
  FD735_RS01320 (FD735_01320) rsmD 229585..230124 (+) 540 WP_000706945.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  FD735_RS01325 (FD735_01325) coaD 230114..230602 (+) 489 WP_139658305.1 pantetheine-phosphate adenylyltransferase -
  FD735_RS01330 (FD735_01330) sepM 230586..231623 (+) 1038 WP_000730772.1 SepM family pheromone-processing serine protease Regulator
  FD735_RS01335 (FD735_01335) - 231679..231909 (+) 231 WP_002892633.1 DUF1146 family protein -
  FD735_RS01340 (FD735_01340) murA 231933..233216 (+) 1284 WP_049505186.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  FD735_RS01345 (FD735_01345) - 233203..233397 (+) 195 WP_000739701.1 DNA-directed RNA polymerase subunit beta -
  FD735_RS01350 (FD735_01350) endA 233438..234262 (+) 825 WP_049505185.1 DNA/RNA non-specific endonuclease Machinery gene
  FD735_RS01355 (FD735_01355) - 234403..235734 (+) 1332 WP_071851874.1 hemolysin family protein -
  FD735_RS01365 (FD735_01365) amiA 236237..238216 (+) 1980 WP_049505183.1 peptide ABC transporter substrate-binding protein Regulator

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29967.71 Da        Isoelectric Point: 9.9965

>NTDB_id=362624 FD735_RS01350 WP_049505185.1 233438..234262(+) (endA) [Streptococcus sp. 1643]
MDKKTRQALIGLLLFLLLAAGSYYIKQMQTAPNTPRTKVSQKKQASEAPSQELAESVLTESLKNQIKGGLEWNGAGAFVV
NGNKTNLDAKVSSKPYADNKTKIVGKETVPTVANALLSKATRQYKNREETGNGSTSWTPPGWHQVKNLKGVYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEDSTGQNYYESLVRKALDQNKRVRYRVTLHYATNENLVPSASQIE
AKSSDGELEFNVLIPNVQKGIQLDYRTGQVTVTN

Nucleotide


Download         Length: 825 bp        

>NTDB_id=362624 FD735_RS01350 WP_049505185.1 233438..234262(+) (endA) [Streptococcus sp. 1643]
ATGGACAAAAAAACAAGACAAGCTCTGATAGGGTTACTTCTATTCTTACTCTTGGCTGCTGGAAGCTACTATATCAAGCA
GATGCAGACAGCGCCAAACACCCCTAGAACCAAGGTTAGTCAGAAAAAACAAGCTTCAGAAGCTCCTAGTCAGGAGTTGG
CAGAAAGTGTCTTAACTGAGTCGCTCAAAAACCAAATCAAGGGGGGACTCGAGTGGAATGGGGCAGGTGCCTTTGTCGTA
AATGGCAATAAAACCAATCTAGATGCCAAGGTTTCCAGCAAACCCTATGCGGATAATAAAACAAAGATAGTTGGAAAAGA
AACAGTCCCAACTGTTGCCAATGCTCTCTTATCCAAAGCGACTCGGCAGTATAAAAATCGTGAAGAAACAGGCAACGGCT
CAACCTCCTGGACGCCACCAGGATGGCATCAGGTCAAGAATCTAAAGGGAGTCTATACACATGCAGTTGATAGAGGACAC
CTGCTGGGCTATGCCTTGATAGGTGGATTAGATGGCTTTGATGCTTCTACCAGCAATCCCAAGAACATTGCAGTTCAGAC
GGCTTGGGCCAACCAGGCTCAGGCGGAAGATTCGACAGGGCAGAACTACTATGAGAGTCTGGTTAGGAAAGCCTTAGATC
AGAATAAGAGAGTCCGTTATCGGGTAACTCTCCACTATGCTACGAATGAGAATTTGGTTCCATCTGCTTCACAAATTGAA
GCCAAGTCTTCAGATGGGGAATTGGAATTCAACGTCCTGATTCCAAATGTTCAAAAGGGTATCCAGCTTGATTACCGAAC
AGGTCAGGTCACGGTGACAAACTAG

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(76-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1L8Q3D7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

88.645

99.635

0.883
  endA Streptococcus pneumoniae D39

88.645

99.635

0.883
  endA Streptococcus pneumoniae R6

88.645

99.635

0.883
  endA Streptococcus pneumoniae TIGR4

88.645

99.635

0.883

Multiple sequence alignment