Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   E3S88_RS06555 Genome accession   NZ_CP047792
Coordinates   1343218..1344480 (-) Length   420 a.a.
NCBI ID   WP_000472293.1    Uniprot ID   Q6GG31
Organism   Staphylococcus aureus strain UP_794     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1338218..1349480
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3S88_RS06530 (E3S88_06530) - 1338416..1339084 (-) 669 WP_124780555.1 uroporphyrinogen-III synthase -
  E3S88_RS06535 (E3S88_06535) hemC 1339106..1340032 (-) 927 WP_124780553.1 hydroxymethylbilane synthase -
  E3S88_RS06540 (E3S88_06540) ccsA 1340074..1340889 (-) 816 WP_001157326.1 cytochrome c biogenesis protein -
  E3S88_RS06545 (E3S88_06545) hemA 1340911..1342257 (-) 1347 WP_095257021.1 glutamyl-tRNA reductase -
  E3S88_RS06550 (E3S88_06550) yihA 1342474..1343064 (-) 591 WP_000867697.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  E3S88_RS06555 (E3S88_06555) clpX 1343218..1344480 (-) 1263 WP_000472293.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  E3S88_RS06560 (E3S88_06560) tig 1344631..1345932 (-) 1302 WP_000127572.1 trigger factor -
  E3S88_RS06565 (E3S88_06565) - 1345980..1346090 (-) 111 WP_001790560.1 hypothetical protein -
  E3S88_RS06570 (E3S88_06570) - 1346095..1347024 (-) 930 WP_001280020.1 hypothetical protein -
  E3S88_RS06575 (E3S88_06575) - 1347043..1347651 (-) 609 WP_000032657.1 NUDIX domain-containing protein -
  E3S88_RS06580 (E3S88_06580) rplT 1347793..1348149 (-) 357 WP_001138360.1 50S ribosomal protein L20 -
  E3S88_RS06585 (E3S88_06585) rpmI 1348196..1348396 (-) 201 WP_001125540.1 50S ribosomal protein L35 -
  E3S88_RS06590 (E3S88_06590) infC 1348425..1348952 (-) 528 WP_001791162.1 translation initiation factor IF-3 -

Sequence

Protein


Download         Length: 420 a.a.        Molecular weight: 46279.44 Da        Isoelectric Point: 4.2645

>NTDB_id=362403 E3S88_RS06555 WP_000472293.1 1343218..1344480(-) (clpX) [Staphylococcus aureus strain UP_794]
MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAITELPTPKEIMDHLNEYVIGQEK
AKKSLAVAVYNHYKRIQQLGPKEDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENIL
LRLIQAADFDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTN
ILFILGGAFDGIEEVIKRRLGEKVIGFSSNEADKYDEQALLAQIRPEDLQAYGLIPEFIGRVPIVANLETLDVTALKNIL
TQPKNALVKQYTKMLELDDVDLEFTEEALSAISEKAIERKTGARGLRSIIEESLIDIMFDVPSNENVTKVVITAQTINEE
TEPELYDAEGNLINNSKTSA

Nucleotide


Download         Length: 1263 bp        

>NTDB_id=362403 E3S88_RS06555 WP_000472293.1 1343218..1344480(-) (clpX) [Staphylococcus aureus strain UP_794]
ATGTTTAAATTCAATGAAGATGAAGAAAATTTGAAATGCTCTTTCTGCGGAAAAGACCAAGATCAAGTAAAAAAACTTGT
AGCAGGAAGTGGTGTATATATTTGTAATGAGTGTATTGAATTATGCTCAGAAATCGTCGAAGAAGAATTAGCTCAAAACA
CTTCTGAAGCGATTACAGAATTACCTACTCCTAAAGAAATTATGGATCATTTAAACGAATATGTTATTGGTCAAGAAAAA
GCTAAAAAATCTTTAGCTGTGGCTGTTTATAACCACTATAAGCGTATTCAACAATTAGGACCAAAAGAAGATGATGTTGA
GTTACAAAAAAGTAACATTGCATTAATTGGGCCAACAGGTAGTGGTAAAACATTATTAGCTCAAACATTAGCCAAGACGT
TGAATGTACCATTTGCAATTGCAGATGCGACAAGTTTAACTGAAGCTGGTTATGTAGGCGATGATGTTGAAAATATCTTG
TTGAGATTAATTCAAGCAGCTGACTTTGACATTGATAAAGCCGAAAAAGGTATTATTTATGTAGATGAAATTGATAAAAT
TGCTCGTAAATCTGAAAACACATCTATAACACGTGACGTTTCAGGTGAAGGTGTTCAACAAGCATTGCTTAAAATCTTAG
AAGGTACAACTGCAAGTGTTCCGCCACAAGGTGGACGCAAACATCCAAACCAAGAAATGATTCAAATTGATACAACAAAT
ATCTTATTTATTCTTGGTGGTGCCTTTGATGGTATTGAAGAAGTGATTAAGCGCCGTCTTGGTGAAAAAGTTATTGGTTT
CTCAAGCAATGAAGCTGATAAATATGACGAACAAGCATTATTAGCACAAATTCGCCCAGAAGATTTGCAAGCCTATGGTT
TGATTCCTGAATTTATCGGACGTGTGCCAATTGTAGCTAATTTAGAAACATTAGATGTAACTGCGTTGAAAAACATCTTA
ACGCAACCTAAAAATGCACTTGTGAAACAATATACTAAAATGCTGGAATTAGATGATGTAGATTTAGAGTTCACTGAAGA
AGCTTTATCAGCAATTAGTGAAAAAGCAATTGAAAGAAAAACAGGTGCGCGTGGTTTACGTTCAATCATAGAAGAATCAT
TAATCGATATTATGTTTGATGTGCCTTCTAACGAAAATGTAACGAAGGTAGTTATTACAGCACAAACAATTAATGAAGAA
ACTGAACCAGAATTATACGACGCAGAAGGTAATTTAATTAATAATAGTAAAACATCAGCTTAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-305)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q6GG31

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

66.917

95

0.636
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.456

94.048

0.531

Multiple sequence alignment