Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   E3T12_RS06985 Genome accession   NZ_CP047779
Coordinates   1425017..1426279 (-) Length   420 a.a.
NCBI ID   WP_000472293.1    Uniprot ID   Q6GG31
Organism   Staphylococcus aureus strain UP_1559     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1420017..1431279
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3T12_RS06960 (E3T12_06960) - 1420215..1420883 (-) 669 WP_000805946.1 uroporphyrinogen-III synthase -
  E3T12_RS06965 (E3T12_06965) hemC 1420905..1421831 (-) 927 WP_001230225.1 hydroxymethylbilane synthase -
  E3T12_RS06970 (E3T12_06970) ccsA 1421873..1422688 (-) 816 WP_001157326.1 cytochrome c biogenesis protein -
  E3T12_RS06975 (E3T12_06975) hemA 1422710..1424056 (-) 1347 WP_000545456.1 glutamyl-tRNA reductase -
  E3T12_RS06980 (E3T12_06980) yihA 1424273..1424863 (-) 591 WP_000867694.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  E3T12_RS06985 (E3T12_06985) clpX 1425017..1426279 (-) 1263 WP_000472293.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  E3T12_RS06990 (E3T12_06990) tig 1426430..1427731 (-) 1302 WP_000127572.1 trigger factor -
  E3T12_RS06995 (E3T12_06995) - 1427779..1427889 (-) 111 WP_001790560.1 hypothetical protein -
  E3T12_RS07000 (E3T12_07000) - 1427894..1428823 (-) 930 WP_001280014.1 hypothetical protein -
  E3T12_RS07005 (E3T12_07005) - 1428842..1429450 (-) 609 WP_000032653.1 NUDIX domain-containing protein -
  E3T12_RS07010 (E3T12_07010) rplT 1429592..1429948 (-) 357 WP_001138360.1 50S ribosomal protein L20 -
  E3T12_RS07015 (E3T12_07015) rpmI 1429995..1430195 (-) 201 WP_001125540.1 50S ribosomal protein L35 -
  E3T12_RS07020 (E3T12_07020) infC 1430224..1430751 (-) 528 WP_001791219.1 translation initiation factor IF-3 -

Sequence

Protein


Download         Length: 420 a.a.        Molecular weight: 46279.44 Da        Isoelectric Point: 4.2645

>NTDB_id=361245 E3T12_RS06985 WP_000472293.1 1425017..1426279(-) (clpX) [Staphylococcus aureus strain UP_1559]
MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAITELPTPKEIMDHLNEYVIGQEK
AKKSLAVAVYNHYKRIQQLGPKEDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENIL
LRLIQAADFDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTN
ILFILGGAFDGIEEVIKRRLGEKVIGFSSNEADKYDEQALLAQIRPEDLQAYGLIPEFIGRVPIVANLETLDVTALKNIL
TQPKNALVKQYTKMLELDDVDLEFTEEALSAISEKAIERKTGARGLRSIIEESLIDIMFDVPSNENVTKVVITAQTINEE
TEPELYDAEGNLINNSKTSA

Nucleotide


Download         Length: 1263 bp        

>NTDB_id=361245 E3T12_RS06985 WP_000472293.1 1425017..1426279(-) (clpX) [Staphylococcus aureus strain UP_1559]
ATGTTTAAATTCAATGAAGATGAAGAAAATTTGAAATGCTCTTTCTGCGGAAAAGACCAAGATCAAGTAAAAAAACTTGT
AGCAGGAAGTGGTGTATATATTTGTAATGAGTGTATTGAATTATGCTCAGAAATCGTCGAAGAAGAATTAGCTCAAAACA
CTTCTGAAGCGATTACAGAATTACCTACTCCTAAAGAAATTATGGATCATTTAAACGAATATGTTATTGGTCAAGAAAAA
GCTAAAAAATCTTTAGCTGTGGCTGTTTATAACCACTATAAGCGTATTCAACAATTAGGACCAAAAGAAGATGATGTTGA
GTTACAAAAAAGTAACATTGCCTTAATTGGGCCAACAGGTAGTGGTAAAACATTATTAGCTCAAACATTAGCCAAGACGT
TGAATGTACCATTTGCAATTGCAGATGCGACAAGTTTAACTGAAGCTGGTTATGTAGGCGATGATGTTGAAAATATCTTG
TTGAGATTAATTCAAGCAGCTGACTTTGACATTGATAAAGCCGAAAAAGGTATTATTTATGTAGATGAAATTGATAAAAT
TGCACGTAAATCTGAAAACACATCTATAACACGTGACGTTTCAGGTGAAGGTGTTCAACAAGCATTGCTTAAAATCTTAG
AAGGTACAACTGCAAGTGTTCCGCCACAAGGTGGACGCAAACATCCAAACCAAGAAATGATTCAAATTGATACAACAAAT
ATCTTATTTATTCTTGGTGGTGCCTTTGATGGTATTGAAGAAGTGATTAAGCGCCGTCTTGGTGAAAAAGTTATTGGTTT
CTCAAGCAATGAAGCTGATAAATATGACGAACAAGCATTATTAGCACAAATTCGCCCAGAAGATTTGCAAGCCTATGGTT
TGATTCCTGAATTTATCGGACGTGTGCCAATTGTAGCTAATTTAGAAACATTAGATGTAACTGCGTTGAAAAACATCTTA
ACGCAACCTAAAAATGCACTTGTGAAACAATATACTAAAATGCTGGAATTAGATGATGTAGATTTAGAGTTCACTGAAGA
AGCTTTATCAGCAATTAGTGAAAAAGCAATTGAAAGAAAAACAGGTGCGCGTGGTTTACGTTCAATCATAGAAGAATCGT
TAATCGATATTATGTTTGATGTGCCTTCTAACGAAAATGTAACGAAGGTAGTTATTACAGCACAAACAATTAATGAAGAA
ACTGAACCAGAATTATACGACGCAGAAGGTAATTTAATTAATAATAGTAAAACATCAGCTTAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-305)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q6GG31

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

66.917

95

0.636
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.456

94.048

0.531

Multiple sequence alignment