Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   GQ601_RS12295 Genome accession   NZ_CP047646
Coordinates   2552398..2553660 (+) Length   420 a.a.
NCBI ID   WP_000472293.1    Uniprot ID   Q6GG31
Organism   Staphylococcus aureus strain 19/Msa0875     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2547398..2558660
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GQ601_RS12260 (GQ601_12320) infC 2547926..2548453 (+) 528 WP_001791162.1 translation initiation factor IF-3 -
  GQ601_RS12265 (GQ601_12325) rpmI 2548482..2548682 (+) 201 WP_001125540.1 50S ribosomal protein L35 -
  GQ601_RS12270 (GQ601_12330) rplT 2548729..2549085 (+) 357 WP_001138360.1 50S ribosomal protein L20 -
  GQ601_RS12275 (GQ601_12335) - 2549227..2549835 (+) 609 WP_000032657.1 NUDIX domain-containing protein -
  GQ601_RS12280 (GQ601_12340) - 2549854..2550783 (+) 930 WP_001280020.1 hypothetical protein -
  GQ601_RS12285 (GQ601_12345) - 2550788..2550898 (+) 111 WP_001790560.1 hypothetical protein -
  GQ601_RS12290 (GQ601_12350) tig 2550946..2552247 (+) 1302 WP_000127572.1 trigger factor -
  GQ601_RS12295 (GQ601_12355) clpX 2552398..2553660 (+) 1263 WP_000472293.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  GQ601_RS12300 (GQ601_12360) yihA 2553814..2554404 (+) 591 WP_000867697.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  GQ601_RS12305 (GQ601_12365) hemA 2554621..2555967 (+) 1347 WP_000545455.1 glutamyl-tRNA reductase -
  GQ601_RS12310 (GQ601_12370) - 2555989..2556804 (+) 816 WP_001157328.1 cytochrome c biogenesis protein -
  GQ601_RS12315 (GQ601_12375) hemC 2556846..2557772 (+) 927 WP_001230221.1 hydroxymethylbilane synthase -
  GQ601_RS12320 (GQ601_12380) - 2557794..2558462 (+) 669 WP_000805952.1 uroporphyrinogen-III synthase -

Sequence

Protein


Download         Length: 420 a.a.        Molecular weight: 46279.44 Da        Isoelectric Point: 4.2645

>NTDB_id=360556 GQ601_RS12295 WP_000472293.1 2552398..2553660(+) (clpX) [Staphylococcus aureus strain 19/Msa0875]
MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAITELPTPKEIMDHLNEYVIGQEK
AKKSLAVAVYNHYKRIQQLGPKEDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENIL
LRLIQAADFDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTN
ILFILGGAFDGIEEVIKRRLGEKVIGFSSNEADKYDEQALLAQIRPEDLQAYGLIPEFIGRVPIVANLETLDVTALKNIL
TQPKNALVKQYTKMLELDDVDLEFTEEALSAISEKAIERKTGARGLRSIIEESLIDIMFDVPSNENVTKVVITAQTINEE
TEPELYDAEGNLINNSKTSA

Nucleotide


Download         Length: 1263 bp        

>NTDB_id=360556 GQ601_RS12295 WP_000472293.1 2552398..2553660(+) (clpX) [Staphylococcus aureus strain 19/Msa0875]
ATGTTTAAATTCAATGAAGATGAAGAAAATTTGAAATGCTCTTTCTGCGGAAAAGACCAAGATCAAGTAAAAAAACTTGT
AGCAGGAAGTGGTGTATATATTTGTAATGAGTGTATTGAATTATGCTCAGAAATCGTCGAAGAAGAATTAGCTCAAAACA
CTTCTGAAGCGATTACAGAATTACCTACTCCTAAAGAAATTATGGATCATTTAAACGAATATGTTATTGGTCAAGAAAAA
GCTAAAAAATCTTTAGCTGTGGCTGTTTATAACCACTATAAGCGTATTCAACAATTAGGACCAAAAGAAGATGATGTTGA
ATTACAAAAAAGTAACATTGCCTTAATTGGGCCAACAGGTAGTGGTAAAACATTATTAGCTCAAACATTAGCCAAGACGT
TGAATGTACCATTTGCAATTGCAGATGCGACAAGTTTAACTGAAGCTGGTTATGTAGGCGATGATGTTGAAAATATCTTG
TTGAGATTAATTCAAGCAGCTGACTTTGACATTGATAAAGCCGAAAAAGGTATTATTTATGTAGATGAAATTGATAAAAT
TGCACGTAAATCTGAAAACACATCTATAACACGTGACGTTTCAGGTGAAGGTGTTCAACAAGCATTGCTTAAAATCTTAG
AAGGTACGACTGCAAGTGTTCCGCCACAAGGTGGACGCAAACATCCAAACCAAGAAATGATTCAAATTGATACAACAAAT
ATCTTATTTATTCTTGGTGGTGCCTTTGATGGTATTGAAGAAGTGATTAAGCGCCGTCTTGGTGAAAAAGTTATTGGTTT
CTCAAGCAATGAAGCTGATAAATATGACGAACAAGCATTATTAGCACAAATTCGCCCAGAAGATTTGCAAGCCTATGGTT
TGATTCCTGAATTTATCGGACGTGTGCCAATTGTAGCTAATTTAGAAACATTAGATGTAACTGCGTTGAAAAACATCTTA
ACGCAACCTAAAAATGCACTTGTGAAACAATATACTAAAATGCTGGAATTAGATGATGTGGATTTAGAGTTCACTGAAGA
AGCTTTATCAGCAATTAGTGAAAAAGCAATTGAAAGAAAAACAGGTGCGCGTGGTTTACGTTCAATCATAGAAGAATCAT
TAATCGATATTATGTTTGATGTGCCTTCTAACGAAAATGTAACGAAGGTAGTTATTACAGCACAAACAATTAATGAAGAA
ACTGAACCAGAACTATACGACGCAGAAGGTAATTTAATTAATAATAGTAAAACATCAGCTTAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-305)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q6GG31

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

66.917

95

0.636
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.456

94.048

0.531