Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   GUU88_RS18265 Genome accession   NZ_CP047594
Coordinates   3766829..3767488 (+) Length   219 a.a.
NCBI ID   WP_160194483.1    Uniprot ID   -
Organism   Escherichia coli strain LD27-1     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 3761829..3772488
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GUU88_RS18240 (GUU88_18240) ygiS 3763112..3764719 (-) 1608 WP_001295629.1 ABC transporter substrate-binding protein -
  GUU88_RS18245 (GUU88_18245) mqsA 3764852..3765247 (-) 396 WP_000650107.1 type II toxin-antitoxin system antitoxin MqsA -
  GUU88_RS18250 (GUU88_18250) mqsR 3765249..3765545 (-) 297 WP_000415584.1 type II toxin-antitoxin system toxin MqsR -
  GUU88_RS18255 (GUU88_18255) ygiV 3765750..3766232 (-) 483 WP_053266176.1 GyrI-like domain-containing protein -
  GUU88_RS18260 (GUU88_18260) ygiW 3766285..3766677 (-) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  GUU88_RS18265 (GUU88_18265) ciaR 3766829..3767488 (+) 660 WP_160194483.1 quorum sensing response regulator transcription factor QseB Regulator
  GUU88_RS18270 (GUU88_18270) qseC 3767485..3768834 (+) 1350 WP_072656973.1 quorum sensing histidine kinase QseC -
  GUU88_RS18275 (GUU88_18275) ygiZ 3768880..3769212 (-) 333 WP_000917684.1 DUF2645 family protein -
  GUU88_RS18280 (GUU88_18280) mdaB 3769531..3770112 (+) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  GUU88_RS18285 (GUU88_18285) ygiN 3770143..3770457 (+) 315 WP_000958598.1 putative quinol monooxygenase -
  GUU88_RS18290 (GUU88_18290) parE 3770505..3772397 (-) 1893 WP_000195296.1 DNA topoisomerase IV subunit B -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24677.59 Da        Isoelectric Point: 6.9850

>NTDB_id=360278 GUU88_RS18265 WP_160194483.1 3766829..3767488(+) (ciaR) [Escherichia coli strain LD27-1]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLLLTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLSRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=360278 GUU88_RS18265 WP_160194483.1 3766829..3767488(+) (ciaR) [Escherichia coli strain LD27-1]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGCTCCTGACCGCG
CGCGATGCGCTGGCGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGTCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGTT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

37.445

100

0.388
  ciaR Streptococcus pneumoniae D39

37.445

100

0.388
  ciaR Streptococcus pneumoniae R6

37.445

100

0.388
  ciaR Streptococcus pneumoniae TIGR4

37.445

100

0.388