Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   GTQ78_RS08710 Genome accession   NZ_CP047571
Coordinates   1818067..1818723 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain 2EC1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1813067..1823723
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GTQ78_RS08680 (GTQ78_08680) dcyD 1813946..1814932 (+) 987 WP_001128227.1 D-cysteine desulfhydrase -
  GTQ78_RS08685 (GTQ78_08685) tcyL 1814947..1815615 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  GTQ78_RS08690 (GTQ78_08690) tcyN 1815612..1816364 (+) 753 WP_001273015.1 L-cystine ABC transporter ATP-binding protein TcyN -
  GTQ78_RS08695 (GTQ78_08695) sdiA 1816594..1817316 (+) 723 WP_005758534.1 transcriptional regulator SdiA -
  GTQ78_RS08700 (GTQ78_08700) yecF 1817384..1817608 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  GTQ78_RS08705 (GTQ78_08705) yecU 1817595..1817771 (-) 177 WP_000590344.1 protein YecU -
  GTQ78_RS24240 - 1817809..1817925 (-) 117 WP_001302039.1 hypothetical protein -
  GTQ78_RS08710 (GTQ78_08710) letA 1818067..1818723 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  GTQ78_RS08715 (GTQ78_08715) uvrC 1818720..1820552 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  GTQ78_RS08720 (GTQ78_08720) pgsA 1820609..1821157 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  GTQ78_RS08740 (GTQ78_08740) - 1821853..1822593 (-) 741 WP_032176377.1 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=360002 GTQ78_RS08710 WP_000611328.1 1818067..1818723(+) (letA) [Escherichia coli strain 2EC1]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=360002 GTQ78_RS08710 WP_000611328.1 1818067..1818723(+) (letA) [Escherichia coli strain 2EC1]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482