Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   I33_RS07190 Genome accession   NC_017195
Coordinates   1413131..1415230 (-) Length   699 a.a.
NCBI ID   WP_041519253.1    Uniprot ID   -
Organism   Bacillus subtilis subsp. subtilis str. RO-NN-1     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 1408131..1420230
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I33_RS07160 (I33_1535) spo0E 1408187..1408444 (+) 258 WP_003218598.1 aspartyl-phosphate phosphatase Spo0E -
  I33_RS07165 (I33_1536) - 1408530..1408961 (+) 432 WP_014476625.1 hypothetical protein -
  I33_RS07170 (I33_1537) kinD 1408989..1410509 (-) 1521 WP_072557174.1 sporulation kinase KinD -
  I33_RS07175 (I33_1538) mhqR 1410702..1411139 (+) 438 WP_003232475.1 MarR family transcriptional regulator MhqR -
  I33_RS07180 (I33_1539) motB 1411179..1411964 (-) 786 WP_003232473.1 flagellar motor protein MotB -
  I33_RS07185 (I33_1540) motA 1411936..1412748 (-) 813 WP_014476627.1 flagellar motor stator protein MotA -
  I33_RS07190 (I33_1541) clpE 1413131..1415230 (-) 2100 WP_041519253.1 ATP-dependent protease ATP-binding subunit ClpE Regulator
  I33_RS07195 (I33_1542) - 1415596..1416639 (+) 1044 WP_014476629.1 membrane protein -
  I33_RS07200 (I33_1543) queC 1416952..1417611 (+) 660 WP_014476630.1 7-cyano-7-deazaguanine synthase QueC -
  I33_RS07205 (I33_1544) queD 1417604..1418053 (+) 450 WP_080009794.1 6-carboxytetrahydropterin synthase QueD -
  I33_RS07210 (I33_1545) queE 1418046..1418777 (+) 732 WP_014476632.1 7-carboxy-7-deazaguanine synthase QueE -
  I33_RS07215 (I33_1546) queF 1418795..1419292 (+) 498 WP_003218613.1 preQ(1) synthase -

Sequence

Protein


Download         Length: 699 a.a.        Molecular weight: 77777.83 Da        Isoelectric Point: 5.1284

>NTDB_id=35965 I33_RS07190 WP_041519253.1 1413131..1415230(-) (clpE) [Bacillus subtilis subsp. subtilis str. RO-NN-1]
MRCQHCQQNEATIRLNMQINSIHKQMVLCETCYNELTRKPSMSMGPQSFGFPFEQAFQPKEHSTAKQSGKKGLLDELAQN
ITNGAKAGLIDPVIGRDDEVARVIEILNRRNKNNPVLIGEPGVGKTAIAEGLALKIAEGDVPNKLKNKELYLLDVASLVA
NTGIRGQFEERMKQLITELKERKNVILFIDEIHLLVGAGSAEGSMDAGNILKPALARGELQVIGATTLKEYRQIEKDAAL
ERRFQPVMVQEPSIEQAILILQGIKDKYEAYHGVTFSDEAIKACVTLSSRYIQDRHLPDKAIDLLDEAGSKANLLIDELN
DEDAAERLTAIEAEKTKALEEENYELAAKLRDEELALEKKLNSSSAHTAVTVEAEHIQEIVEQKTGIPVGKLQADEQTKM
KELEAKLHERVIGQEAAVQKVAKAVRRSRAGLKSKNRPVGSFLFVGPTGVGKTELSKTLADELFGTKDAIIRLDMSEYME
KHAVSKIIGSPPGYVGHEEAGQLTEKVRRNPYSIVLLDEIEKAHPDVQHMFLQIMEDGRLTDSQGRTVSFKDTVIIMTSN
AGAGEKQTKVGFQSDDSVIEEQTLIDSLSMFFKPEFLNRFDSIIEFRSLEKEHLVKIVSLLLGELEETLAERGISLNVTD
EAKEKIAELGYHPSFGARPLRRTIQEWVEDEMTDLLLDNGGITSFHVILEDDKIKVQAK

Nucleotide


Download         Length: 2100 bp        

>NTDB_id=35965 I33_RS07190 WP_041519253.1 1413131..1415230(-) (clpE) [Bacillus subtilis subsp. subtilis str. RO-NN-1]
ATGCGTTGTCAACATTGTCAGCAAAACGAGGCGACGATTCGCCTTAACATGCAAATAAATTCAATTCATAAACAGATGGT
TCTGTGTGAAACTTGCTATAACGAACTGACCCGTAAACCTTCAATGAGTATGGGTCCTCAGTCTTTCGGATTTCCGTTTG
AACAGGCATTCCAGCCGAAAGAACACAGCACAGCAAAACAAAGCGGAAAAAAAGGGTTGCTTGATGAGCTGGCTCAAAAT
ATTACAAATGGTGCAAAAGCCGGTCTTATTGACCCCGTCATCGGCCGTGACGATGAAGTGGCGCGAGTGATCGAAATTCT
AAACCGCCGAAACAAAAACAATCCGGTTCTTATTGGTGAGCCGGGTGTAGGGAAAACTGCCATCGCTGAAGGGCTCGCTT
TAAAAATTGCTGAAGGTGATGTTCCAAACAAACTGAAAAACAAAGAGCTATATTTGCTTGATGTTGCATCCCTTGTTGCA
AACACAGGGATCAGAGGCCAATTTGAGGAGAGAATGAAACAGCTGATCACTGAGCTGAAGGAACGAAAAAATGTCATTCT
GTTCATTGATGAAATTCACCTTCTCGTCGGCGCAGGCTCTGCAGAAGGATCAATGGACGCCGGCAACATTCTCAAACCGG
CCTTAGCCAGAGGCGAACTGCAAGTCATTGGCGCGACAACACTAAAAGAATATCGTCAAATCGAAAAAGACGCCGCGCTG
GAAAGACGTTTTCAGCCTGTCATGGTACAGGAGCCTTCAATTGAACAGGCTATCCTCATTCTGCAAGGGATTAAAGACAA
ATACGAGGCGTACCATGGCGTAACATTCAGTGATGAAGCAATCAAAGCGTGTGTCACTTTATCATCCCGCTACATTCAGG
ACAGACACCTGCCGGATAAAGCAATTGATTTATTAGATGAAGCAGGTTCAAAAGCCAACCTGTTAATTGATGAACTGAAT
GACGAGGATGCCGCTGAACGCTTAACTGCAATTGAAGCCGAAAAAACAAAAGCCCTGGAAGAAGAAAATTACGAACTGGC
GGCAAAACTCCGTGATGAAGAACTCGCATTGGAGAAAAAACTGAACAGCTCCTCCGCTCATACCGCTGTCACTGTGGAAG
CTGAGCACATTCAGGAAATTGTTGAACAAAAAACAGGCATCCCTGTCGGCAAACTGCAGGCAGACGAACAAACGAAAATG
AAAGAACTCGAAGCAAAACTTCATGAACGCGTGATTGGACAAGAAGCCGCTGTTCAAAAAGTGGCAAAGGCGGTAAGACG
GAGTCGCGCCGGTTTAAAATCCAAAAACAGACCAGTCGGCTCCTTCCTCTTCGTAGGTCCTACCGGCGTAGGGAAAACAG
AGCTTTCTAAAACACTAGCAGATGAATTATTCGGGACAAAAGACGCTATTATCCGACTCGATATGAGCGAATACATGGAG
AAACACGCCGTATCTAAAATTATCGGTTCACCGCCTGGATATGTCGGCCATGAGGAAGCTGGACAATTAACTGAGAAAGT
GCGCCGCAATCCTTACAGCATTGTGTTGCTGGATGAGATTGAAAAAGCACACCCAGACGTTCAGCATATGTTCCTGCAAA
TTATGGAAGATGGCCGTCTGACAGACAGCCAAGGCAGAACCGTAAGCTTTAAAGACACTGTGATCATCATGACAAGTAAT
GCGGGTGCTGGTGAGAAACAAACGAAAGTCGGTTTCCAATCAGATGACAGTGTCATCGAAGAACAAACATTGATTGATTC
ACTGAGCATGTTCTTTAAACCTGAGTTCCTCAACCGTTTTGACAGCATTATTGAGTTCCGCTCATTGGAAAAAGAACATC
TGGTCAAAATCGTCAGTCTTCTTCTTGGAGAACTTGAAGAAACATTGGCTGAACGGGGCATCAGCTTGAATGTGACAGAT
GAAGCGAAAGAAAAAATCGCTGAGCTGGGCTACCACCCTTCATTCGGTGCACGTCCGCTTAGAAGAACCATCCAAGAATG
GGTTGAGGATGAAATGACCGATCTGCTGCTTGATAATGGCGGGATCACAAGTTTTCACGTGATTTTAGAAGATGATAAAA
TCAAAGTGCAAGCGAAATAA

Domains

Predicted by InterProScan.

AAA lid domain (AAA_lid_9)

(253-352)

ATPase family associated with various cellular activities (AAA) (AAA)

(116-247)

AAA domain (Cdc48 subfamily) (AAA_2)

(437-603)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(609-679)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

57.261

100

0.592
  clpC Lactococcus lactis subsp. cremoris KW2

56.148

100

0.588
  clpE Streptococcus pneumoniae TIGR4

55.062

100

0.568
  clpE Streptococcus pneumoniae Rx1

55.062

100

0.568
  clpE Streptococcus pneumoniae D39

55.062

100

0.568
  clpE Streptococcus pneumoniae R6

55.062

100

0.568
  clpC Bacillus subtilis subsp. subtilis str. 168

54.016

90.844

0.491
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.967

91.989

0.432
  clpC Streptococcus thermophilus LMD-9

45.763

92.847

0.425
  clpC Streptococcus pneumoniae D39

46.457

90.844

0.422
  clpC Streptococcus pneumoniae Rx1

46.457

90.844

0.422
  clpC Streptococcus pneumoniae TIGR4

46.299

90.844

0.421
  clpC Streptococcus thermophilus LMG 18311

45.3

92.847

0.421
  clpC Streptococcus mutans UA159

46.417

87.84

0.408
  clpA Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

41.914

86.695

0.363

Multiple sequence alignment