Detailed information NTG0359526

Bioinformatically predicted

Overview

• Name: comA/comEC
• Type: Machinery gene
• Locus tag: EA714_RS04270
• Genome accession: NZ_CP039520
• Coordinates: 906609..909041 (+)
• Length: 810 a.a.
• NCBI ID: WP_000472705.1
• Uniprot ID: A0A231SZ39
• Organism: Acinetobacter baumannii strain TG22627
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Prophage	901579..913718	906609..909041	within	0

Gene organization within MGE regions

Location: 901579..913718

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EA714_RS18895	-	901579..901725 (-)	147	WP_000691794.1	hypothetical protein	-
EA714_RS04245 (EA714_004245)	-	901759..902700 (-)	942	WP_000795874.1	hypothetical protein	-
EA714_RS04250 (EA714_004250)	-	902957..903442 (+)	486	WP_001985538.1	YaiI/YqxD family protein	-
EA714_RS04255 (EA714_004255)	-	903453..904361 (+)	909	WP_001140078.1	DMT family transporter	-
EA714_RS04260 (EA714_004260)	-	904609..905844 (+)	1236	WP_001984636.1	lipoprotein-releasing ABC transporter permease subunit	-
EA714_RS04265 (EA714_004265)	lolD	905837..906523 (+)	687	WP_000049403.1	lipoprotein-releasing ABC transporter ATP-binding protein LolD	-
EA714_RS04270 (EA714_004270)	comA/comEC	906609..909041 (+)	2433	WP_000472705.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
EA714_RS04275 (EA714_004275)	-	908994..909977 (-)	984	WP_001984639.1	lysophospholipid acyltransferase family protein	-
EA714_RS04280 (EA714_004280)	sppA	910114..911130 (+)	1017	WP_001286615.1	signal peptide peptidase SppA	-
EA714_RS04285 (EA714_004285)	-	911149..911958 (+)	810	WP_000114076.1	alpha/beta fold hydrolase	-
EA714_RS04290 (EA714_004290)	purN	912022..912651 (-)	630	WP_000975536.1	phosphoribosylglycinamide formyltransferase	-
EA714_RS04295 (EA714_004295)	purM	912648..913718 (-)	1071	WP_000071984.1	phosphoribosylformylglycinamidine cyclo-ligase	-

Sequence

Protein

• Length: 810 a.a.
• Molecular weight: 92426.69 Da
• Isoelectric Point: 8.6357

>NTDB_id=359526 EA714_RS04270 WP_000472705.1 906609..909041(+) (comA/comEC) [Acinetobacter baumannii strain TG22627]
MFKIILLGWIGGIALMGIDFPLIMQYEKVGEALLLLAFIFYLYKRPMFVDRPFLKAVFCLLCTTSLFMVGYHYAEKALIE
RLEQRETDTRNLDIIVYINRLSEEKDNKVQQTAQVLNFSKEPVNWLLYLKSNNQNLLKNNQNLELGHYYRISGKTRPAHS
YATPGAFDQEKWFIQRNIMSGFNVRYIEPLSLDEIYRLGYQQHLKEQQSFSNSFRLNIEKLRLTFRQILNSSSLQQKGLI
LALLTGDESLLSDETQLQFKQLGISHLLAISGPHVLIFAIMLSWACHQFISRYYPQIYLWKPKQVLMAVPCCLGVLIYTA
FVGFEIPALRTLLSAFIFIGFLLLKQPIKPFTLLVYSASLLLLIDPFSVLSAGFWLSYGACFILLRIYQTIAQLPEQQFL
SLSSKMIFMGKVLIESQGKIFIALSPLTLLFFQQISWVAPLTNIIAVPIVGGVIVPLNIMAACAWFIVKPFGNMLFHFND
MLLSILLSCLGLLEKLSLPLQGISLTPLSLLAISFAIIILFLPKGILPKTWGILCCLPLVIMNKTSQQIQLNILDVGQGQ
AIFLQHSEQNWLIDTGGSYDEKIFSIGQNVVVPFLRQQGVRQLDHVVLSHLDQDHSGAFPLIQQEIPVKQLISNEQLPND
LKQPFQYCHQGQQWHYPELDIQILWPKEKDLAFVASNQNQYSCVVYLQFKKVGGYQNFLIMGDAGWEAEYELLKDYPNLK
IDVLVLGHHGSKHSSAYDFLATLKPKLAIASAGFDNRYGHPSQQVIARLKALHIPLKSTVEQGTLSFVLENHKIVLHDRR
LDRLWLSRGF

Nucleotide

• Length: 2433 bp

>NTDB_id=359526 EA714_RS04270 WP_000472705.1 906609..909041(+) (comA/comEC) [Acinetobacter baumannii strain TG22627]
ATGTTTAAGATTATTCTATTGGGGTGGATTGGCGGTATTGCATTGATGGGAATAGATTTCCCTTTAATCATGCAATATGA
AAAAGTGGGCGAGGCTCTACTGTTACTTGCCTTTATTTTTTATCTTTATAAACGACCAATGTTCGTTGATCGACCATTTT
TAAAGGCAGTGTTTTGCTTATTATGTACAACAAGTCTTTTTATGGTTGGTTACCACTATGCTGAAAAAGCACTGATTGAA
CGATTAGAACAAAGAGAAACGGATACCCGAAATCTCGACATTATTGTTTATATAAACCGTTTAAGTGAAGAAAAAGATAA
TAAGGTTCAACAAACTGCACAAGTTCTAAATTTTTCTAAAGAACCGGTGAATTGGTTGCTATATTTAAAAAGTAATAATC
AAAATTTATTAAAGAATAATCAGAATCTTGAATTAGGTCACTATTATCGAATATCTGGAAAAACAAGACCTGCGCATAGT
TATGCCACCCCAGGAGCTTTTGATCAGGAAAAATGGTTTATTCAGCGAAATATTATGTCTGGTTTTAATGTGAGATATAT
TGAGCCTTTAAGTCTCGATGAAATCTATCGATTGGGCTATCAGCAACATTTAAAAGAACAACAGTCTTTTTCCAATAGTT
TTCGTTTAAATATAGAAAAACTTCGCTTAACTTTTAGGCAAATATTAAACAGCTCATCTCTACAGCAAAAGGGTTTAATT
TTAGCTTTGCTGACAGGTGATGAAAGCCTTTTATCAGATGAAACTCAACTACAGTTCAAACAATTAGGAATTAGTCATTT
ATTGGCGATCTCAGGCCCACATGTGCTCATTTTTGCCATTATGTTATCTTGGGCATGTCATCAATTTATCAGTCGTTATT
ATCCTCAAATTTACTTATGGAAACCGAAACAGGTTTTGATGGCTGTACCATGCTGCCTTGGTGTTTTAATTTATACTGCA
TTTGTAGGTTTCGAAATTCCTGCACTACGAACATTATTATCAGCATTTATATTTATTGGATTTCTATTATTAAAACAACC
TATTAAACCTTTTACATTACTCGTATATAGCGCAAGTCTACTGTTGCTAATTGACCCGTTTAGTGTGCTTTCTGCAGGTT
TTTGGCTGTCTTATGGGGCATGCTTTATTTTATTAAGAATTTACCAAACTATAGCGCAGCTACCTGAGCAACAGTTTTTA
AGTCTGAGCTCAAAAATGATTTTTATGGGTAAGGTGTTAATTGAGTCTCAAGGCAAAATATTTATTGCATTGAGTCCCTT
AACCTTACTTTTCTTTCAACAAATTTCTTGGGTTGCTCCATTAACCAATATTATTGCCGTGCCTATTGTTGGTGGTGTTA
TTGTCCCTTTAAACATCATGGCTGCTTGCGCATGGTTTATAGTAAAACCGTTTGGAAATATGCTTTTTCATTTCAATGAT
ATGTTGCTCAGCATATTGCTGAGTTGTTTGGGCTTATTAGAAAAACTCTCTTTACCATTACAAGGTATAAGCTTGACGCC
ACTGTCTTTATTAGCGATTAGTTTTGCCATAATTATTTTATTTTTACCTAAAGGAATTCTGCCCAAAACTTGGGGGATAT
TATGTTGTTTACCCTTAGTTATTATGAACAAAACGAGTCAACAAATTCAGCTTAATATTTTAGATGTTGGACAGGGGCAA
GCCATTTTTTTACAACATTCCGAACAAAACTGGTTAATTGATACAGGCGGTTCTTACGATGAAAAAATATTTAGTATTGG
ACAAAATGTTGTAGTGCCTTTTCTACGTCAGCAAGGCGTAAGACAATTAGATCATGTTGTGCTATCCCATCTTGATCAAG
ACCATAGTGGCGCGTTTCCTCTTATTCAACAAGAGATTCCTGTAAAGCAGCTTATTTCGAATGAACAATTACCAAATGAT
TTAAAGCAACCATTCCAATATTGCCATCAAGGGCAACAATGGCATTATCCTGAGTTAGATATTCAAATTTTATGGCCTAA
AGAAAAAGATCTGGCTTTTGTTGCTTCTAACCAGAATCAATATTCTTGTGTTGTATATCTTCAATTTAAAAAAGTTGGTG
GTTACCAAAATTTTCTTATTATGGGCGATGCAGGATGGGAAGCCGAATACGAGTTATTAAAAGATTATCCTAACTTGAAG
ATAGATGTGTTGGTGCTAGGGCATCATGGAAGTAAGCACAGTTCGGCTTATGATTTCTTGGCGACCTTAAAACCTAAACT
GGCCATTGCATCGGCAGGGTTTGATAACCGTTATGGCCATCCTAGCCAACAAGTTATAGCACGTTTAAAAGCTCTACATA
TTCCGCTAAAAAGCACTGTGGAACAAGGGACCTTAAGTTTTGTGTTGGAAAATCACAAAATAGTTTTACATGACCGACGT
TTGGATAGGCTCTGGTTGAGTAGAGGTTTTTAA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (33-188)

• Metallo-beta-lactamase superfamily (Lactamase_B) (555-639)

• Competence protein (Competence) (243-521)

3D structure

• AlphaFold DB: A0A231SZ39

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/comEC	Acinetobacter baumannii D1279779	98.025	100	0.98
comA/comEC	Acinetobacter baumannii strain A118	97.037	100	0.97
comA/comEC	Acinetobacter baylyi ADP1	50.246	100	0.504