Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   MS6193_RS10330 Genome accession   NZ_CP047405
Coordinates   2126144..2126800 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain MS6193     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2121144..2131800
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MS6193_RS10300 (MS6193_02094) yecA 2122395..2123060 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  MS6193_RS10320 (MS6193_02098) pgsA 2123710..2124258 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  MS6193_RS10325 (MS6193_02099) uvrC 2124315..2126147 (-) 1833 WP_001283437.1 excinuclease ABC subunit UvrC Machinery gene
  MS6193_RS10330 (MS6193_02100) letA 2126144..2126800 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  MS6193_RS25805 - 2126942..2127013 (+) 72 Protein_2056 transcriptional regulator -
  MS6193_RS10335 yecU 2127096..2127272 (+) 177 WP_000590347.1 protein YecU -
  MS6193_RS10340 (MS6193_02101) yecF 2127259..2127483 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  MS6193_RS10345 (MS6193_02102) sdiA 2127550..2128272 (-) 723 WP_001154271.1 transcriptional regulator SdiA -
  MS6193_RS10350 (MS6193_02103) tcyN 2128502..2129254 (-) 753 WP_001273009.1 L-cystine ABC transporter ATP-binding protein TcyN -
  MS6193_RS10355 (MS6193_02104) tcyL 2129251..2129919 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  MS6193_RS10360 (MS6193_02105) dcyD 2129934..2130920 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=359515 MS6193_RS10330 WP_000611335.1 2126144..2126800(-) (letA) [Escherichia coli strain MS6193]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=359515 MS6193_RS10330 WP_000611335.1 2126144..2126800(-) (letA) [Escherichia coli strain MS6193]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486

Multiple sequence alignment