Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   E8M06_RS08450 Genome accession   NZ_CP039462
Coordinates   1714855..1715544 (-) Length   229 a.a.
NCBI ID   WP_002942700.1    Uniprot ID   A0A126UNE5
Organism   Streptococcus suis strain WUSS351     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1709855..1720544
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E8M06_RS08425 (E8M06_08435) - 1710325..1711038 (-) 714 WP_024399628.1 NADPH-dependent oxidoreductase -
  E8M06_RS08430 (E8M06_08440) dnaI 1711035..1711934 (-) 900 WP_044752054.1 primosomal protein DnaI -
  E8M06_RS08435 (E8M06_08445) - 1711934..1713085 (-) 1152 WP_105120084.1 replication initiation/membrane attachment protein -
  E8M06_RS08440 (E8M06_08450) nrdR 1713072..1713563 (-) 492 WP_002938341.1 transcriptional regulator NrdR -
  E8M06_RS08445 (E8M06_08455) - 1713635..1714765 (-) 1131 WP_024390116.1 AI-2E family transporter -
  E8M06_RS08450 (E8M06_08460) covR 1714855..1715544 (-) 690 WP_002942700.1 winged helix-turn-helix domain-containing protein Regulator
  E8M06_RS08455 (E8M06_08465) gndA 1715626..1717053 (-) 1428 WP_002942698.1 NADP-dependent phosphogluconate dehydrogenase -
  E8M06_RS08460 (E8M06_08470) - 1717150..1717689 (-) 540 WP_014736258.1 DUF177 domain-containing protein -
  E8M06_RS08465 (E8M06_08475) trxB 1717699..1718616 (-) 918 WP_002942687.1 thioredoxin-disulfide reductase -
  E8M06_RS08470 (E8M06_08480) - 1718630..1718854 (-) 225 WP_014638521.1 DUF4059 family protein -
  E8M06_RS08475 (E8M06_08485) - 1718872..1720215 (-) 1344 WP_044756307.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26225.11 Da        Isoelectric Point: 5.3968

>NTDB_id=358861 E8M06_RS08450 WP_002942700.1 1714855..1715544(-) (covR) [Streptococcus suis strain WUSS351]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELAAELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=358861 E8M06_RS08450 WP_002942700.1 1714855..1715544(-) (covR) [Streptococcus suis strain WUSS351]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTGCAGAACTATTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACTGAAGTTAGTCAATATGGGGAAGAAGTTCTCTCTTATGCTGTTTCCTACGTAGTGAAGCCCTTTGTCAT
CAGTGATTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGATTTTATTGACAATAACTGTAAACAGGTTCACATGC
ATGCGGCCTATCGCGATTTGAAGGTTGATTTTCAAAATCGAACAGTAACTCGAGGTGATGAATTGATTAATTTGACCCGC
CGAGAGTATGATCTGTTGGCGACCTTAATGAATAGCCCAGAGCCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATAAAAACAGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A126UNE5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432

Multiple sequence alignment