Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   E8M03_RS13970 Genome accession   NZ_CP039448
Coordinates   2750505..2751170 (-) Length   221 a.a.
NCBI ID   WP_000697884.1    Uniprot ID   -
Organism   Staphylococcus aureus strain VGC1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2745505..2756170
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E8M03_RS13950 (E8M03_14110) - 2745965..2746078 (-) 114 WP_078065157.1 hypothetical protein -
  E8M03_RS13955 (E8M03_14115) - 2746747..2748747 (-) 2001 WP_000776726.1 ABC transporter permease -
  E8M03_RS13960 (E8M03_14120) - 2748744..2749499 (-) 756 WP_000923775.1 ABC transporter ATP-binding protein -
  E8M03_RS13965 (E8M03_14125) braS 2749607..2750494 (-) 888 WP_000143422.1 nisin susceptibility-associated two-component system sensor histidine kinase NsaS Regulator
  E8M03_RS13970 (E8M03_14130) braR 2750505..2751170 (-) 666 WP_000697884.1 nisin susceptibility-associated two-component system response regulator NsaR Regulator
  E8M03_RS13975 (E8M03_14135) - 2751196..2751396 (-) 201 WP_000604725.1 hypothetical protein -
  E8M03_RS13980 (E8M03_14140) - 2751594..2753018 (+) 1425 WP_000953738.1 alkaline phosphatase -
  E8M03_RS14920 (E8M03_14145) - 2753078..2753179 (-) 102 WP_000731972.1 SE2200 family small protein -
  E8M03_RS13990 (E8M03_14150) - 2753301..2753756 (-) 456 WP_000106183.1 MarR family winged helix-turn-helix transcriptional regulator -
  E8M03_RS13995 (E8M03_14155) - 2754001..2754762 (-) 762 WP_000323448.1 alpha/beta hydrolase family protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25406.50 Da        Isoelectric Point: 4.7961

>NTDB_id=358691 E8M03_RS13970 WP_000697884.1 2750505..2751170(-) (braR) [Staphylococcus aureus strain VGC1]
MKILIVEDDFVIAESLASELKKWNYGVIVVEQFDDILSIFNQHQPQLVLLDINLPTLNGFHWCQEIRKTSNVPIIFISSR
IDNMDQIMAIQMGGDDFIEKPFNLSLTIAKIQALLRRTYDLSVANDSMTVKGCTLILDEAKVVYQEQSIQLSLTELQILK
LLFQNEDKYVSRTALIEKCWESENFIDDNTLAVNMTRLRKKLNTIGVNDFIITKKNVGYKV

Nucleotide


Download         Length: 666 bp        

>NTDB_id=358691 E8M03_RS13970 WP_000697884.1 2750505..2751170(-) (braR) [Staphylococcus aureus strain VGC1]
ATGAAAATATTAATTGTTGAAGATGATTTTGTTATAGCAGAAAGTTTAGCATCTGAACTTAAAAAATGGAATTACGGTGT
TATTGTCGTTGAACAATTTGATGATATACTGTCTATCTTTAACCAACATCAACCTCAGCTTGTATTGCTAGATATTAATT
TGCCAACGTTAAATGGTTTTCATTGGTGTCAAGAAATCCGAAAAACATCTAATGTGCCAATTATATTTATTAGTTCCCGT
ATTGATAATATGGACCAAATTATGGCAATACAAATGGGGGGAGATGATTTTATCGAAAAACCATTTAATTTGTCATTAAC
GATTGCCAAAATTCAAGCATTATTGAGACGAACTTATGACTTGTCAGTAGCTAATGATTCGATGACGGTTAAAGGTTGTA
CATTAATATTAGATGAAGCAAAAGTCGTGTATCAAGAACAAAGCATACAGCTATCTTTGACTGAATTACAAATATTAAAG
TTATTATTTCAAAATGAAGATAAATATGTAAGTAGAACTGCTTTAATTGAAAAATGTTGGGAATCAGAAAACTTCATAGA
TGATAACACATTAGCTGTTAACATGACGCGCCTGCGTAAAAAATTAAATACTATTGGCGTTAATGATTTTATCATTACAA
AGAAAAATGTCGGATATAAAGTATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)

Response regulator receiver domain (Response_reg)

(3-111)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

99.095

100

0.991

Multiple sequence alignment