Detailed information NTG0358690

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: E8M03_RS13965
• Genome accession: NZ_CP039448
• Coordinates: 2749607..2750494 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143422.1
• Uniprot ID: A0AB73JC73
• Organism: Staphylococcus aureus strain VGC1
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2744607..2755494

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E8M03_RS13930 (E8M03_14090)	-	2744616..2744708 (+)	93	WP_010956583.1	hypothetical protein	-
E8M03_RS13935 (E8M03_14095)	-	2744816..2745313 (-)	498	WP_001065268.1	glutathione peroxidase	-
E8M03_RS13940 (E8M03_14100)	-	2745323..2745583 (-)	261	WP_011382405.1	hypothetical protein	-
E8M03_RS13950 (E8M03_14110)	-	2745965..2746078 (-)	114	WP_078065157.1	hypothetical protein	-
E8M03_RS13955 (E8M03_14115)	-	2746747..2748747 (-)	2001	WP_000776726.1	ABC transporter permease	-
E8M03_RS13960 (E8M03_14120)	-	2748744..2749499 (-)	756	WP_000923775.1	ABC transporter ATP-binding protein	-
E8M03_RS13965 (E8M03_14125)	braS	2749607..2750494 (-)	888	WP_000143422.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
E8M03_RS13970 (E8M03_14130)	braR	2750505..2751170 (-)	666	WP_000697884.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
E8M03_RS13975 (E8M03_14135)	-	2751196..2751396 (-)	201	WP_000604725.1	hypothetical protein	-
E8M03_RS13980 (E8M03_14140)	-	2751594..2753018 (+)	1425	WP_000953738.1	alkaline phosphatase	-
E8M03_RS14920 (E8M03_14145)	-	2753078..2753179 (-)	102	WP_000731972.1	SE2200 family small protein	-
E8M03_RS13990 (E8M03_14150)	-	2753301..2753756 (-)	456	WP_000106183.1	MarR family winged helix-turn-helix transcriptional regulator	-
E8M03_RS13995 (E8M03_14155)	-	2754001..2754762 (-)	762	WP_000323448.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34031.29 Da
• Isoelectric Point: 5.8962

>NTDB_id=358690 E8M03_RS13965 WP_000143422.1 2749607..2750494(-) (braS) [Staphylococcus aureus strain VGC1]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGVGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=358690 E8M03_RS13965 WP_000143422.1 2749607..2750494(-) (braS) [Staphylococcus aureus strain VGC1]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTGTTGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99