Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   E8M03_RS06395 Genome accession   NZ_CP039448
Coordinates   1283906..1284778 (+) Length   290 a.a.
NCBI ID   WP_000620183.1    Uniprot ID   A0A6B1RG35
Organism   Staphylococcus aureus strain VGC1     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1278906..1289778
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E8M03_RS06370 (E8M03_06440) - 1279051..1279818 (+) 768 WP_000176399.1 ribonuclease HII -
  E8M03_RS06375 (E8M03_06445) sucC 1279927..1281093 (+) 1167 WP_001020801.1 ADP-forming succinate--CoA ligase subunit beta -
  E8M03_RS06380 (E8M03_06450) sucD 1281115..1282023 (+) 909 WP_000110253.1 succinate--CoA ligase subunit alpha -
  E8M03_RS06385 (E8M03_06455) - 1282310..1282462 (+) 153 Protein_1229 cell wall hydrolase -
  E8M03_RS06390 (E8M03_06460) fmhC 1282490..1283734 (+) 1245 WP_000672856.1 FemA/FemB family glycyltransferase FmhC -
  E8M03_RS06395 (E8M03_06465) dprA 1283906..1284778 (+) 873 WP_000620183.1 DNA-processing protein DprA Machinery gene
  E8M03_RS06400 (E8M03_06470) topA 1284951..1287026 (+) 2076 WP_001838647.1 type I DNA topoisomerase -
  E8M03_RS06405 (E8M03_06475) trmFO 1287182..1288489 (+) 1308 WP_000195254.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -

Sequence

Protein


Download         Length: 290 a.a.        Molecular weight: 33532.95 Da        Isoelectric Point: 9.5191

>NTDB_id=358662 E8M03_RS06395 WP_000620183.1 1283906..1284778(+) (dprA) [Staphylococcus aureus strain VGC1]
MIRLFLLKLYWAHFSTKQIHQFLMAYPNVIKEGGRKKDSYLCEWVNREENVHLLRKYYAFIKLDHNDIIKELQKLKVSYI
TYMDTEYPVLLKEIYQFPLLLFYKGNINLINNMHHLAVVGARDSTSYTQQSLEFLLSNDKSKYLTIVSGLAQGADAMAHQ
IALKYNLPTIAVLAFGHQIHYPKSTLALRNKIEEKGLVISEYPPHTPIAKYRFPERNRIISGLSKGVLITEAKEQSGSHI
TIDFALEQNRNVYVLPGSMFNPMTKGNLLRIQEGAKVVLNANDIFEDYYI

Nucleotide


Download         Length: 873 bp        

>NTDB_id=358662 E8M03_RS06395 WP_000620183.1 1283906..1284778(+) (dprA) [Staphylococcus aureus strain VGC1]
TTGATTAGACTATTTTTGCTTAAGTTATACTGGGCACACTTTTCGACTAAACAAATTCATCAATTTTTAATGGCATATCC
TAATGTAATTAAAGAGGGGGGCAGAAAAAAAGATAGTTATTTATGTGAATGGGTGAATAGGGAAGAAAATGTTCATTTAT
TACGTAAATACTATGCTTTTATAAAACTTGATCATAACGATATTATTAAAGAACTGCAGAAATTAAAAGTAAGTTACATT
ACATATATGGATACTGAATACCCAGTGCTATTAAAAGAAATATATCAATTTCCATTACTTCTTTTCTATAAAGGGAACAT
AAATTTAATAAATAATATGCATCATTTGGCAGTAGTAGGTGCAAGAGATTCTACAAGTTATACCCAACAGTCTTTAGAAT
TTTTATTATCAAATGATAAAAGCAAATATTTAACAATTGTTTCCGGCCTTGCTCAAGGAGCTGATGCAATGGCACATCAA
ATAGCTTTAAAATACAATCTCCCTACAATAGCAGTTTTAGCCTTTGGCCATCAAATACATTATCCCAAAAGTACATTAGC
ATTAAGAAATAAAATAGAAGAAAAAGGTTTAGTTATATCCGAATATCCACCACATACACCAATTGCTAAATATAGATTTC
CTGAGCGCAATAGAATTATCAGCGGTTTGTCAAAAGGGGTTTTAATTACTGAGGCTAAGGAACAAAGTGGCAGTCACATC
ACGATAGATTTTGCATTAGAGCAAAATAGAAATGTTTATGTTTTACCTGGATCTATGTTTAATCCTATGACAAAAGGTAA
TTTATTACGTATCCAAGAAGGAGCTAAGGTAGTATTAAACGCTAATGATATATTTGAAGACTACTATATTTAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(72-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6B1RG35

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Staphylococcus aureus MW2

98.276

100

0.983
  dprA Staphylococcus aureus N315

97.931

100

0.979

Multiple sequence alignment