Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   GRI05_RS05620 Genome accession   NZ_CP047248
Coordinates   1142120..1143904 (-) Length   594 a.a.
NCBI ID   WP_012775432.1    Uniprot ID   A0A0H3MW45
Organism   Streptococcus suis strain LSM178     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1137120..1148904
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GRI05_RS05605 (GRI05_05745) - 1139880..1140044 (-) 165 WP_012775058.1 hypothetical protein -
  GRI05_RS05610 (GRI05_05750) obgE 1140418..1141731 (-) 1314 WP_011922805.1 GTPase ObgE -
  GRI05_RS05615 (GRI05_05755) - 1141935..1142063 (-) 129 WP_002935474.1 DUF4044 domain-containing protein -
  GRI05_RS05620 (GRI05_05760) uvrC 1142120..1143904 (-) 1785 WP_012775432.1 excinuclease ABC subunit UvrC Machinery gene
  GRI05_RS05625 (GRI05_05765) - 1144144..1144887 (+) 744 WP_011922278.1 ABC transporter ATP-binding protein -
  GRI05_RS05630 (GRI05_05770) - 1144884..1146494 (+) 1611 WP_011922277.1 permease -
  GRI05_RS05635 (GRI05_05775) - 1146522..1146965 (-) 444 WP_002935466.1 VOC family protein -
  GRI05_RS05640 (GRI05_05780) ldcB 1147054..1147809 (-) 756 WP_012775056.1 LD-carboxypeptidase LdcB/DacB -
  GRI05_RS05645 (GRI05_05785) - 1148160..1148411 (-) 252 WP_012775055.1 phage holin -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68141.24 Da        Isoelectric Point: 8.9394

>NTDB_id=358487 GRI05_RS05620 WP_012775432.1 1142120..1143904(-) (uvrC) [Streptococcus suis strain LSM178]
MNDLIKHKLELLPDSPGCYLHKNKYGKIIYVGKAKNLRNRVRSYFRGAHDTKTEALVAEIADFEFIVTDSNIEALLLEIN
LIQENKPRYNIMLKDDKSYPFIKITKERHPRLLITRQIKKDGGQYFGPYPDVGAANQTLKLLERLYPFRKCKLPENKYCL
YYHLGQCLAHGDNMPSLSDYDKMAKEVAQFLTGHDDKIIKEVQDKMKAAAGNLEFEKAAEYRDVLQSISTLRTKQRVMAH
DLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERNVNLFPYYNDAGEDFLTYIGQFYRDQQHLIPSEVLIPQDIDQEAVEAL
VDTKVIKPQRGEKKQLINLATKNARVSLEQKFNLLEKNLEKTYGAVENIGQLLGIPTPVRIEAFDNSNIMGTSPVSAMVV
FENGVPNKKEYRKYKINTVEGPDDYASMREVLQRRYSRVLRDGLTPPDLIIIDGGQGQVNVAKQVIEQELGMSIPIAGLQ
KNDKHQTHELLFGNPLEVVELPRNSQEFFLLHRIQDEVHRFAIEFHRQVRSKNSFSSKLDGIEGLGPKRKQTLMKHFKSI
GNIQSASLQEIAEAGVPYKVAEKVKESLSSKDEI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=358487 GRI05_RS05620 WP_012775432.1 1142120..1143904(-) (uvrC) [Streptococcus suis strain LSM178]
ATGAACGATTTGATCAAGCATAAATTGGAGTTACTACCAGATAGCCCTGGCTGTTACCTCCATAAAAACAAGTACGGTAA
GATTATCTATGTGGGCAAGGCCAAAAACCTACGCAATCGGGTGCGGTCTTATTTTCGTGGTGCCCATGATACCAAGACAG
AGGCTCTAGTGGCTGAAATTGCCGATTTTGAATTTATCGTGACGGATTCCAACATCGAGGCCCTCTTGCTAGAAATCAAT
CTGATTCAGGAAAACAAGCCACGCTATAACATCATGCTCAAGGATGACAAGTCTTATCCCTTCATCAAGATTACCAAGGA
ACGTCATCCACGGCTGCTCATTACTCGGCAGATTAAGAAGGATGGTGGTCAGTATTTTGGTCCCTATCCAGATGTGGGTG
CGGCCAACCAGACCCTCAAACTATTGGAGCGCCTCTATCCTTTCCGCAAGTGTAAATTGCCTGAGAACAAGTATTGTCTT
TATTATCATTTGGGGCAATGTTTGGCTCATGGAGACAATATGCCCAGCCTGTCTGACTATGACAAGATGGCCAAGGAAGT
GGCCCAGTTCTTGACAGGTCATGATGATAAGATTATCAAGGAAGTGCAGGACAAGATGAAGGCAGCTGCTGGCAATTTGG
AATTTGAAAAGGCTGCGGAATACCGGGATGTCCTCCAATCCATTTCAACCCTGCGGACCAAGCAACGTGTGATGGCTCAT
GACTTGCAGAATCGAGATGTCTTTGGCTACTACGTAGACAAGGGCTGGATGTGTGTGCAGGTTTTCTTTGTTCGGCAGGG
GAAACTGATTGAGCGGAATGTCAATCTTTTTCCATACTATAATGATGCGGGCGAAGACTTTTTGACCTACATCGGTCAGT
TTTACAGGGACCAGCAACATTTGATTCCCTCAGAGGTCTTGATACCGCAGGATATTGACCAAGAAGCCGTAGAAGCTCTG
GTAGATACCAAGGTCATCAAGCCCCAGCGTGGCGAGAAGAAGCAACTCATCAATCTGGCAACCAAGAATGCGCGTGTCAG
TCTGGAGCAGAAGTTTAATCTTTTGGAGAAAAATCTGGAGAAGACCTACGGTGCGGTGGAGAATATCGGTCAGCTTTTGG
GGATTCCGACGCCTGTGCGGATTGAGGCTTTCGATAACTCCAATATTATGGGGACTAGTCCTGTGTCGGCTATGGTTGTC
TTTGAAAATGGGGTGCCTAATAAAAAAGAATACCGCAAGTACAAGATTAATACGGTTGAGGGACCGGATGACTATGCTTC
CATGCGGGAAGTTTTGCAGCGGCGGTACAGTCGGGTGCTGCGGGACGGTTTGACACCGCCTGATTTGATTATCATTGACG
GTGGTCAGGGGCAGGTCAATGTCGCCAAGCAGGTCATCGAGCAGGAGTTGGGTATGTCCATTCCCATTGCAGGTTTGCAG
AAGAATGACAAGCACCAGACACACGAATTGCTCTTTGGTAATCCGCTGGAAGTAGTTGAGTTGCCTCGCAATTCACAGGA
ATTTTTCCTCCTGCATCGGATTCAAGATGAGGTTCACCGCTTTGCTATTGAGTTTCATCGTCAGGTTCGGTCAAAAAATT
CCTTCTCATCCAAATTGGACGGCATAGAAGGCTTGGGACCAAAACGCAAGCAGACTTTGATGAAGCATTTCAAGTCTATT
GGCAATATCCAGTCGGCCAGTCTACAAGAAATCGCAGAAGCAGGAGTGCCGTATAAAGTAGCGGAAAAGGTCAAGGAAAG
CCTTTCTTCAAAGGATGAGATTTGA

Domains

Predicted by InterProScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)

UvrB/uvrC motif (UVR)

(196-229)

GIY-YIG catalytic domain (GIY-YIG)

(17-90)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3MW45

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

76.728

99.832

0.766
  uvrC Streptococcus pneumoniae R6

76.391

99.832

0.763
  uvrC Streptococcus pneumoniae D39

76.391

99.832

0.763

Multiple sequence alignment