Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   E4T61_RS05995 Genome accession   NZ_CP039297
Coordinates   1157445..1158101 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis isolate UFLA258     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1152445..1163101
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E4T61_RS05970 (E4T61_05970) oppF 1152974..1153891 (+) 918 WP_012117283.1 oligopeptide ABC transporter ATP-binding protein OppF -
  E4T61_RS05975 (E4T61_05975) - 1153998..1155185 (+) 1188 WP_059367234.1 putative glycoside hydrolase -
  E4T61_RS05980 (E4T61_05980) - 1155303..1155881 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  E4T61_RS05985 (E4T61_05985) spx 1156060..1156455 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  E4T61_RS05990 (E4T61_05990) - 1156513..1157169 (-) 657 WP_007409109.1 TerC family protein -
  E4T61_RS19790 - 1157352..1157462 (+) 111 Protein_1114 adaptor protein MecA -
  E4T61_RS05995 (E4T61_05995) mecA 1157445..1158101 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  E4T61_RS06000 (E4T61_06000) - 1158252..1159412 (+) 1161 WP_059367231.1 competence protein CoiA family protein -
  E4T61_RS06005 (E4T61_06005) pepF 1159640..1161469 (+) 1830 WP_094031915.1 oligoendopeptidase F Regulator
  E4T61_RS19685 - 1161507..1161674 (-) 168 WP_003155026.1 hypothetical protein -
  E4T61_RS06010 (E4T61_06010) spxH 1161960..1162862 (-) 903 WP_136396266.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=358002 E4T61_RS05995 WP_003155032.1 1157445..1158101(+) (mecA) [Bacillus velezensis isolate UFLA258]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=358002 E4T61_RS05995 WP_003155032.1 1157445..1158101(+) (mecA) [Bacillus velezensis isolate UFLA258]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment