Detailed information NTG0357909

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: GQY29_RS05190
• Genome accession: NZ_CP047191
• Coordinates: 962160..962945 (+)
• Length: 261 a.a.
• NCBI ID: WP_002951720.1
• Uniprot ID: Q5M305
• Organism: Streptococcus thermophilus strain EU01
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 957160..967945

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GQY29_RS05165 (GQY29_05165)	pflA	957436..958236 (+)	801	WP_002946980.1	pyruvate formate-lyase-activating protein	-
GQY29_RS05170 (GQY29_05170)	-	958472..958822 (+)	351	WP_236552684.1	hypothetical protein	-
GQY29_RS10350	-	958883..959056 (+)	174	WP_011681546.1	hypothetical protein	-
GQY29_RS05175 (GQY29_05175)	-	959128..959699 (-)	572	Protein_935	IS30 family transposase	-
GQY29_RS05180 (GQY29_05180)	-	959879..960331 (-)	453	WP_002946987.1	universal stress protein	-
GQY29_RS05185 (GQY29_05185)	-	960686..961900 (+)	1215	WP_002951721.1	pyridoxal phosphate-dependent aminotransferase	-
GQY29_RS05190 (GQY29_05190)	codY	962160..962945 (+)	786	WP_002951720.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
GQY29_RS05195 (GQY29_05195)	-	963008..963559 (+)	552	WP_002946999.1	isochorismatase family cysteine hydrolase	-
GQY29_RS05200 (GQY29_05200)	-	963683..964531 (+)	849	WP_024703985.1	MetQ/NlpA family ABC transporter substrate-binding protein	-
GQY29_RS05205 (GQY29_05205)	msrA	964543..965052 (+)	510	WP_024703984.1	peptide-methionine (S)-S-oxide reductase MsrA	-
GQY29_RS05210 (GQY29_05210)	-	965205..966646 (+)	1442	Protein_942	6-phospho-beta-glucosidase	-
GQY29_RS10725	-	967083..967247 (+)	165	WP_231838381.1	glycosyltransferase	-
GQY29_RS05220 (GQY29_05220)	-	967186..967404 (+)	219	WP_014621899.1	glycosyl transferase	-
GQY29_RS05225 (GQY29_05225)	gatC	967579..967881 (+)	303	WP_002884769.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	-

Sequence

Protein

• Length: 261 a.a.
• Molecular weight: 28919.13 Da
• Isoelectric Point: 4.5802

>NTDB_id=357909 GQY29_RS05190 WP_002951720.1 962160..962945(+) (codY) [Streptococcus thermophilus strain EU01]
MANLLDKTRKITSILQRSVDSLEGDLPYNNMAAQLADIIDCNAAIVNGGGALLGFAMKYKTNNDRVEKFFKAKQLPEEYI
RGISRVYDTQENIGIDSDLTIFPVELKDDFPDGLTTIAPIYGGGMRLGSFIIWRNDHDFVDDDLILVEIASTVVGLQLLH
LQTENLEETIRKQTAINMAINTLSYSEIKAVSAILNELDGLEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLNEGIYDKLKEYE

Nucleotide

• Length: 786 bp

>NTDB_id=357909 GQY29_RS05190 WP_002951720.1 962160..962945(+) (codY) [Streptococcus thermophilus strain EU01]
ATGGCAAATTTGCTTGATAAAACACGTAAAATTACTTCTATCTTGCAACGCTCAGTAGATAGTTTGGAAGGAGATCTTCC
ATACAACAACATGGCTGCTCAGTTGGCAGATATTATTGATTGTAATGCTGCTATTGTAAATGGTGGAGGTGCTCTCCTTG
GTTTTGCTATGAAATACAAAACCAACAATGACCGTGTGGAAAAGTTTTTTAAAGCTAAACAACTTCCAGAGGAATACATA
CGTGGTATCAGCCGTGTTTATGATACTCAAGAAAATATCGGTATTGACAGTGACTTGACCATCTTCCCAGTGGAATTAAA
AGATGATTTCCCTGACGGTTTGACTACAATTGCACCAATCTATGGTGGTGGTATGCGTCTTGGTTCTTTCATTATTTGGC
GTAACGACCATGATTTTGTGGACGACGACCTTATCTTGGTTGAGATTGCATCTACAGTAGTTGGTTTGCAATTGTTGCAT
CTTCAAACAGAAAACTTGGAAGAAACGATTCGTAAACAAACAGCTATTAATATGGCTATTAATACCTTGTCTTACTCAGA
AATCAAGGCAGTTTCAGCTATCTTGAATGAGTTGGACGGTTTAGAAGGTCGTTTGACAGCCTCTGTTATCGCGGACCGTA
TCGGAATTACTCGTTCTGTTATTGTTAATGCTCTTCGTAAATTAGAATCAGCTGGTATTATTGAAAGTCGTTCGCTTGGT
ATGAAAGGCACTTACCTTAAAGTCCTTAACGAAGGTATCTACGACAAATTGAAAGAATACGAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (3-182)

• CodY helix-turn-helix domain (HTH_CodY) (201-261)

3D structure

• AlphaFold DB: Q5M305

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Lactococcus lactis subsp. lactis strain DGCC12653	64.591	98.467	0.636
codY	Bacillus subtilis subsp. subtilis str. 168	53.036	94.636	0.502