Detailed information NTG0357746

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: GR131_RS12750
• Genome accession: NZ_CP047147
• Coordinates: 2993722..2994843 (+)
• Length: 373 a.a.
• NCBI ID: WP_030770839.1
• Uniprot ID: A0ABY3GYB8
• Organism: Streptomyces sp. GF20
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 2988722..2999843

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GR131_RS12730 (GR131_12730)	-	2989148..2989369 (-)	222	WP_003948872.1	hypothetical protein	-
GR131_RS12735 (GR131_12735)	-	2989483..2991225 (-)	1743	WP_010645242.1	sigma factor-like helix-turn-helix DNA-binding protein	-
GR131_RS12740 (GR131_12740)	-	2991504..2992079 (+)	576	WP_003948874.1	dihydrofolate reductase family protein	-
GR131_RS12745 (GR131_12745)	radA/sms	2992133..2993551 (+)	1419	WP_003948876.1	DNA repair protein RadA	Machinery gene
GR131_RS12750 (GR131_12750)	disA	2993722..2994843 (+)	1122	WP_030770839.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
GR131_RS12755 (GR131_12755)	-	2994927..2995745 (-)	819	WP_236570758.1	hypothetical protein	-
GR131_RS12760 (GR131_12760)	-	2996101..2996850 (+)	750	WP_008404973.1	phosphatase PAP2 family protein	-
GR131_RS12765 (GR131_12765)	-	2996963..2998015 (+)	1053	WP_008404974.1	A/G-specific adenine glycosylase	-
GR131_RS12770 (GR131_12770)	-	2998234..2998773 (+)	540	WP_003948881.1	SigE family RNA polymerase sigma factor	-
GR131_RS12775 (GR131_12775)	-	2998794..2999462 (+)	669	WP_018895477.1	hypothetical protein	-

Sequence

Protein

• Length: 373 a.a.
• Molecular weight: 40273.14 Da
• Isoelectric Point: 5.1034

>NTDB_id=357746 GR131_RS12750 WP_030770839.1 2993722..2994843(+) (disA) [Streptomyces sp. GF20]
MAANDRATAPGKSGGPGADGLMRASLSAVAPGTQLRDGLERILRGNTGGLIVLGWDRTVESMCTGGFVLDVEFSATRLRE
LCKLDGGIVLDKDLTKILRAGVQLVPDPTIPTDETGTRHRTADRVSKQVNFPVVSVSQSMRLIALYVDGQRRVLEDSAAI
LSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVSQRLEMVRRIAAEIAEYVVELGTDGRLLALQLDELIAG
VEPERELVVRDYVPEPTAKRSRTVDEALTELGKLSHTELLELPVVARALGYTGSPEALDSAVSPRGFRLLAKVPRLPGAI
IDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1122 bp

>NTDB_id=357746 GR131_RS12750 WP_030770839.1 2993722..2994843(+) (disA) [Streptomyces sp. GF20]
GTGGCAGCCAATGACCGGGCAACGGCCCCCGGCAAGTCCGGCGGGCCCGGTGCCGACGGGCTGATGCGTGCCTCGCTGAG
CGCCGTCGCCCCCGGCACCCAGCTGCGGGACGGGCTGGAGCGGATTCTGCGGGGGAACACCGGCGGACTCATCGTGCTCG
GCTGGGACAGGACCGTCGAGTCGATGTGTACCGGCGGCTTCGTGCTGGACGTCGAGTTCTCCGCGACCCGCCTGCGCGAG
CTGTGCAAGCTCGACGGCGGCATCGTCCTCGACAAGGACCTCACCAAGATCCTGCGCGCCGGAGTCCAGCTCGTCCCCGA
CCCGACCATCCCCACCGACGAGACCGGCACCCGGCACCGCACCGCCGACCGCGTCTCCAAGCAGGTCAACTTCCCCGTGG
TCTCGGTCAGCCAGTCGATGCGGCTGATCGCGCTCTACGTGGACGGGCAGCGCCGGGTCCTGGAGGACTCGGCCGCCATC
CTCTCCCGCGCCAACCAGGCCCTCGCGACGCTGGAGCGGTACAAGCTCCGGCTGGACGAGGTGGCCGGCACGCTCTCGGC
GCTGGAGATCGAGGACCTGGTGACGGTCCGCGACGTCACGGCCGTCTCGCAGCGGCTGGAGATGGTCCGCCGGATCGCCG
CCGAGATCGCCGAGTACGTGGTGGAACTGGGCACCGACGGGCGTCTGCTCGCCCTCCAGCTGGACGAGCTGATCGCCGGC
GTCGAGCCCGAACGCGAGCTGGTCGTCCGGGACTACGTGCCGGAACCCACGGCGAAGCGTTCCCGGACGGTGGACGAGGC
GCTGACGGAGCTGGGCAAACTCAGCCACACCGAGCTGCTCGAACTGCCCGTGGTGGCGCGGGCGCTCGGCTACACCGGCT
CGCCGGAGGCGCTGGACTCGGCGGTGTCGCCGCGCGGCTTCCGCCTCCTGGCGAAGGTGCCGCGGCTGCCCGGGGCCATC
ATCGACCGGCTGGTGGAGCACTTCGGCGGCCTCCAGAAGCTGCTGGCGGCCAGTGTGGACGACCTGCAGACGGTGGACGG
CGTCGGCGAGGCCCGCGCCCGCAGCGTCCGCGAGGGCCTCTCCCGCCTGGCCGAGTCGTCGATCCTGGAGCGGTACGTCT
GA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (37-150)

• Helix-hairpin-helix motif (HHH_2) (323-358)

• DisA bacterial checkpoint controller linker region (DisA-linker) (154-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	46.532	92.761	0.432