Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   E1949_RS13380 Genome accession   NZ_CP039160
Coordinates   2611934..2612599 (-) Length   221 a.a.
NCBI ID   WP_000697877.1    Uniprot ID   A0A0D1JN68
Organism   Staphylococcus aureus strain Lr6     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2606934..2617599
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E1949_RS13360 (E1949_13600) - 2607404..2607517 (-) 114 WP_011447078.1 hypothetical protein -
  E1949_RS13365 (E1949_13605) - 2608176..2610176 (-) 2001 WP_048538652.1 ABC transporter permease -
  E1949_RS13370 (E1949_13610) - 2610173..2610928 (-) 756 WP_000923760.1 ABC transporter ATP-binding protein -
  E1949_RS13375 (E1949_13615) braS 2611036..2611923 (-) 888 WP_000143427.1 nisin susceptibility-associated two-component system sensor histidine kinase NsaS Regulator
  E1949_RS13380 (E1949_13620) braR 2611934..2612599 (-) 666 WP_000697877.1 nisin susceptibility-associated two-component system response regulator NsaR Regulator
  E1949_RS13385 (E1949_13625) - 2612625..2612825 (-) 201 WP_000604727.1 hypothetical protein -
  E1949_RS13390 (E1949_13630) - 2613023..2614447 (+) 1425 WP_000953748.1 alkaline phosphatase -
  E1949_RS14540 (E1949_13635) - 2614507..2614608 (-) 102 WP_000731976.1 SE2200 family small protein -
  E1949_RS13400 (E1949_13640) - 2614730..2615185 (-) 456 WP_000106185.1 MarR family winged helix-turn-helix transcriptional regulator -
  E1949_RS13405 (E1949_13645) - 2615430..2616191 (-) 762 WP_000323441.1 alpha/beta hydrolase family protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25415.49 Da        Isoelectric Point: 4.7961

>NTDB_id=357316 E1949_RS13380 WP_000697877.1 2611934..2612599(-) (braR) [Staphylococcus aureus strain Lr6]
MKILIVEDDFVIAESLASELKKWNYGVIVVEQFDDILSIFNQHQPQLVLLDINLPTLNGFHWCQEIRKTSNVPIIFISSR
IDNMDQIMAIQMGGDDFIEKPFNLSLTIAKIQALLRRTYDLSVANDSLTVKGCTLILDEAKVVYQEQNIQLSLTELQILK
LLFQNEDKYVSRTALIEKCWESENFIDDNTLAVNMTRLRKKLNTIGVNDFIITKKNVGYKV

Nucleotide


Download         Length: 666 bp        

>NTDB_id=357316 E1949_RS13380 WP_000697877.1 2611934..2612599(-) (braR) [Staphylococcus aureus strain Lr6]
ATGAAAATATTAATTGTTGAAGATGATTTTGTTATAGCAGAAAGTTTAGCATCTGAACTTAAAAAATGGAATTACGGTGT
TATTGTCGTTGAACAATTTGATGATATACTGTCTATCTTTAACCAACATCAACCTCAGCTTGTATTGCTAGATATTAATT
TGCCAACGTTAAATGGTTTTCATTGGTGTCAAGAAATCCGAAAAACATCTAATGTGCCAATTATATTTATTAGTTCCCGT
ATTGATAATATGGACCAAATTATGGCAATACAAATGGGGGGAGATGATTTTATCGAAAAACCATTTAACTTGTCATTAAC
GATTGCCAAAATACAAGCATTATTGAGACGAACTTATGACTTGTCAGTAGCTAATGATTCATTGACGGTTAAAGGTTGTA
CATTAATATTAGATGAAGCAAAAGTCGTGTATCAAGAACAAAACATACAGCTATCTTTGACTGAATTACAAATATTAAAG
TTATTATTTCAAAATGAAGATAAATATGTAAGTAGAACTGCTTTAATTGAAAAATGTTGGGAATCAGAAAACTTCATAGA
TGATAACACATTAGCTGTTAACATGACACGCCTGCGTAAAAAATTAAATACTATTGGCGTTAATGATTTTATCATTACAA
AGAAAAATGTCGGATATAAAGTATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-111)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0D1JN68

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

100

100

1

Multiple sequence alignment