Detailed information NTG0357315

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: E1949_RS13375
• Genome accession: NZ_CP039160
• Coordinates: 2611036..2611923 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143427.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain Lr6
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2606036..2616923

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E1949_RS13340 (E1949_13580)	-	2606064..2606147 (+)	84	WP_031797553.1	hypothetical protein	-
E1949_RS13345 (E1949_13585)	-	2606255..2606752 (-)	498	WP_001065268.1	glutathione peroxidase	-
E1949_RS13350 (E1949_13590)	-	2606762..2607022 (-)	261	WP_001789910.1	hypothetical protein	-
E1949_RS13360 (E1949_13600)	-	2607404..2607517 (-)	114	WP_011447078.1	hypothetical protein	-
E1949_RS13365 (E1949_13605)	-	2608176..2610176 (-)	2001	WP_048538652.1	ABC transporter permease	-
E1949_RS13370 (E1949_13610)	-	2610173..2610928 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
E1949_RS13375 (E1949_13615)	braS	2611036..2611923 (-)	888	WP_000143427.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
E1949_RS13380 (E1949_13620)	braR	2611934..2612599 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
E1949_RS13385 (E1949_13625)	-	2612625..2612825 (-)	201	WP_000604727.1	hypothetical protein	-
E1949_RS13390 (E1949_13630)	-	2613023..2614447 (+)	1425	WP_000953748.1	alkaline phosphatase	-
E1949_RS14540 (E1949_13635)	-	2614507..2614608 (-)	102	WP_000731976.1	SE2200 family small protein	-
E1949_RS13400 (E1949_13640)	-	2614730..2615185 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
E1949_RS13405 (E1949_13645)	-	2615430..2616191 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34058.35 Da
• Isoelectric Point: 5.6439

>NTDB_id=357315 E1949_RS13375 WP_000143427.1 2611036..2611923(-) (braS) [Staphylococcus aureus strain Lr6]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHYEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=357315 E1949_RS13375 WP_000143427.1 2611036..2611923(-) (braS) [Staphylococcus aureus strain Lr6]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATTACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993