Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   E1949_RS09740 Genome accession   NZ_CP039160
Coordinates   1915201..1915830 (-) Length   209 a.a.
NCBI ID   WP_000153528.1    Uniprot ID   -
Organism   Staphylococcus aureus strain Lr6     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1910201..1920830
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E1949_RS09710 (E1949_09880) - 1910622..1911152 (-) 531 WP_000184383.1 acyl-CoA thioesterase -
  E1949_RS09715 (E1949_09885) - 1911242..1912498 (-) 1257 WP_075583716.1 aminopeptidase -
  E1949_RS09720 (E1949_09890) - 1912501..1912701 (-) 201 WP_000180460.1 DUF1128 family protein -
  E1949_RS09725 (E1949_09895) - 1912848..1913312 (+) 465 WP_000228666.1 low molecular weight protein-tyrosine-phosphatase -
  E1949_RS09730 (E1949_09900) - 1913319..1913594 (+) 276 WP_000428172.1 YtxH domain-containing protein -
  E1949_RS09735 (E1949_09905) - 1913872..1915089 (+) 1218 WP_000037078.1 YihY/virulence factor BrkB family protein -
  E1949_RS09740 (E1949_09910) vraR 1915201..1915830 (-) 630 WP_000153528.1 two-component system response regulator VraR Regulator
  E1949_RS09745 (E1949_09915) vraS 1915820..1916863 (-) 1044 WP_001017131.1 sensor histidine kinase Regulator
  E1949_RS09750 (E1949_09920) liaF 1916860..1917561 (-) 702 WP_000149064.1 cell wall-active antibiotics response protein LiaF -
  E1949_RS09755 (E1949_09925) - 1917576..1917962 (-) 387 WP_001110179.1 hypothetical protein -
  E1949_RS09760 (E1949_09930) map 1918179..1918937 (-) 759 WP_000636142.1 type I methionyl aminopeptidase -
  E1949_RS09765 (E1949_09935) - 1919409..1920395 (+) 987 WP_000999718.1 aromatic acid exporter family protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23527.26 Da        Isoelectric Point: 5.3889

>NTDB_id=357309 E1949_RS09740 WP_000153528.1 1915201..1915830(-) (vraR) [Staphylococcus aureus strain Lr6]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMDDMDGVEATTQIKKDLPQIKVL
ILTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=357309 E1949_RS09740 WP_000153528.1 1915201..1915830(-) (vraR) [Staphylococcus aureus strain Lr6]
ATGACGATTAAAGTATTGTTTGTGGATGATCATGAAATGGTACGTATAGGAATTTCAAGTTATCTATCAACGCAAAGTGA
TATTGAAGTAGTTGGTGAAGGCGCTTCTGGTAAAGAAGCAATTGCCAAAGCCCATGAGTTGAAGCCAGATTTAATTTTAA
TGGATTTACTTATGGATGACATGGATGGTGTAGAAGCGACGACTCAGATTAAAAAAGATTTACCGCAAATTAAAGTATTA
ATATTAACTAGTTTTATTGAAGATAAAGAGGTATATCGTGCATTAGATGCAGGTGTCGATAGTTACATTTTAAAAACAAC
AAGTGCAAAAGATATCGCCGATGCAGTTCGTAAAACTTCTAGAGGAGAATCTGTTTTTGAACCGGAAGTTTTAGTGAAAA
TGCGTAACCGTATGAAAAAGCGCGCAGAGTTATATGAAATGCTTACAGAACGAGAAATGGAAATATTATTATTGATTGCG
AAAGGTTACTCAAATCAAGAAATTGCTAGTGCATCGCATATTACTATTAAAACGGTTAAGACACATGTGAGTAACATTTT
AAGTAAGTTAGAAGTGCAAGATAGAACACAAGCTGTCATCTATGCATTCCAACATAATTTAATTCAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

99.043

100

0.99
  degU Bacillus subtilis subsp. subtilis str. 168

35.268

100

0.378

Multiple sequence alignment