Detailed information    

insolico Bioinformatically predicted

Overview

Name   comK/comK1   Type   Regulator
Locus tag   E1949_RS04625 Genome accession   NZ_CP039160
Coordinates   923916..924485 (-) Length   189 a.a.
NCBI ID   WP_048538800.1    Uniprot ID   -
Organism   Staphylococcus aureus strain Lr6     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 918916..929485
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E1949_RS04600 (E1949_04680) - 919229..920404 (+) 1176 Protein_883 S1C family serine protease -
  E1949_RS04605 (E1949_04685) - 920421..921779 (+) 1359 WP_000021865.1 TrkH family potassium uptake protein -
  E1949_RS04610 (E1949_04690) - 921918..923429 (+) 1512 WP_000414165.1 bifunctional UDP-sugar hydrolase/5'-nucleotidase -
  E1949_RS04625 (E1949_04705) comK/comK1 923916..924485 (-) 570 WP_048538800.1 competence protein ComK Regulator
  E1949_RS04630 (E1949_04710) - 924695..924913 (+) 219 WP_000876826.1 IDEAL domain-containing protein -
  E1949_RS04635 (E1949_04715) - 924994..925980 (-) 987 WP_000668818.1 lipoate--protein ligase -
  E1949_RS04640 (E1949_04720) - 926179..926355 (+) 177 WP_000214898.1 YkvS family protein -
  E1949_RS04645 (E1949_04725) - 926370..926972 (+) 603 WP_001033865.1 CPBP family glutamic-type intramembrane protease -
  E1949_RS14355 - 927287..927349 (+) 63 WP_228764722.1 hypothetical protein -
  E1949_RS04655 (E1949_04735) - 927888..927989 (+) 102 WP_031763719.1 hypothetical protein -
  E1949_RS04660 (E1949_04740) - 928011..928271 (+) 261 WP_033860750.1 lactococcin 972 family bacteriocin -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 22569.77 Da        Isoelectric Point: 9.6091

>NTDB_id=357286 E1949_RS04625 WP_048538800.1 923916..924485(-) (comK/comK1) [Staphylococcus aureus strain Lr6]
MYSQNIYVIRKGDMVIRPAFDDDDQRNGSEIIRFDKTRIQNPFKVQKIIERSCKFYGNTYLGKKAETNRITGISSKPPIL
LTPLFPTYFFPTHSDRQNENIWLNMHYIESIKELKNRKCKVTFINNESIILHVSYHSLWHQYNNSIFYYYVVDKQSRMIS
KNPDQPIDYNKATLNVFEALTRYSLFEDK

Nucleotide


Download         Length: 570 bp        

>NTDB_id=357286 E1949_RS04625 WP_048538800.1 923916..924485(-) (comK/comK1) [Staphylococcus aureus strain Lr6]
ATGTATTCTCAAAATATTTATGTGATACGCAAAGGAGACATGGTTATTCGACCAGCATTTGATGATGACGATCAAAGAAA
CGGTAGTGAAATAATTCGGTTTGACAAAACGCGTATTCAAAATCCTTTTAAAGTCCAGAAAATCATTGAACGCTCTTGCA
AATTTTATGGTAATACTTATCTTGGCAAGAAAGCAGAGACAAACCGCATTACTGGCATTTCTAGTAAACCACCTATTTTA
CTAACACCATTATTTCCAACTTATTTTTTCCCAACACATTCTGACAGACAAAATGAAAATATTTGGTTAAATATGCATTA
TATCGAAAGTATTAAAGAATTAAAAAATCGTAAATGTAAAGTGACATTTATTAATAATGAATCTATCATTCTTCATGTTT
CATACCACAGTTTATGGCATCAATATAACAATTCCATTTTTTACTATTACGTGGTAGATAAACAATCTCGCATGATATCA
AAAAATCCCGACCAACCAATAGATTATAATAAAGCCACATTGAATGTGTTTGAAGCATTGACACGCTATTCTTTATTTGA
AGATAAATAA

Domains

Predicted by InterproScan.

ComK protein (ComK)

(5-156)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comK/comK1 Staphylococcus aureus MW2

99.471

100

0.995
  comK/comK1 Staphylococcus aureus N315

99.471

100

0.995

Multiple sequence alignment