Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   E1949_RS02445 Genome accession   NZ_CP039160
Coordinates   492140..492709 (+) Length   189 a.a.
NCBI ID   WP_000872864.1    Uniprot ID   -
Organism   Staphylococcus aureus strain Lr6     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 487140..497709
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E1949_RS02420 (E1949_02470) cysE 488353..489000 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  E1949_RS02425 (E1949_02475) cysS 488984..490384 (+) 1401 WP_000631974.1 cysteine--tRNA ligase -
  E1949_RS02430 (E1949_02480) - 490377..490781 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  E1949_RS02435 (E1949_02485) rlmB 490789..491535 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  E1949_RS02440 (E1949_02490) - 491535..492059 (+) 525 WP_000664738.1 NYN domain-containing protein -
  E1949_RS02445 (E1949_02495) sigH 492140..492709 (+) 570 WP_000872864.1 sigma-70 family RNA polymerase sigma factor Regulator
  E1949_RS02450 (E1949_02500) rpmG 492824..492967 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  E1949_RS02455 (E1949_02505) secE 493023..493205 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  E1949_RS02460 (E1949_02510) nusG 493218..493766 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  E1949_RS02465 (E1949_02515) rplK 493947..494369 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  E1949_RS02470 (E1949_02520) rplA 494577..495269 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  E1949_RS02480 (E1949_02530) rplJ 495541..496041 (+) 501 WP_001273087.1 50S ribosomal protein L10 -
  E1949_RS02485 (E1949_02535) rplL 496084..496452 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  E1949_RS02490 (E1949_02540) - 496627..497235 (+) 609 WP_000020302.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23097.96 Da        Isoelectric Point: 9.6015

>NTDB_id=357280 E1949_RS02445 WP_000872864.1 492140..492709(+) (sigH) [Staphylococcus aureus strain Lr6]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLKPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNQLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=357280 E1949_RS02445 WP_000872864.1 492140..492709(+) (sigH) [Staphylococcus aureus strain Lr6]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTAAAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATCAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.413

100

0.984
  sigH Staphylococcus aureus N315

97.354

100

0.974

Multiple sequence alignment