Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   GQ584_RS10700 Genome accession   NZ_CP047057
Coordinates   2152500..2153156 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli NC101     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2147500..2158156
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GQ584_RS10670 (GQ584_10540) yecA 2148752..2149417 (-) 666 WP_000847882.1 UPF0149 family protein YecA -
  GQ584_RS10690 (GQ584_10560) pgsA 2150066..2150614 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  GQ584_RS10695 (GQ584_10565) uvrC 2150671..2152503 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  GQ584_RS10700 (GQ584_10570) letA 2152500..2153156 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  GQ584_RS10705 (GQ584_10575) yecU 2153452..2153628 (+) 177 WP_001307856.1 protein YecU -
  GQ584_RS10710 (GQ584_10580) yecF 2153615..2153839 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  GQ584_RS10715 (GQ584_10585) sdiA 2153907..2154629 (-) 723 WP_001154255.1 transcriptional regulator SdiA -
  GQ584_RS10720 (GQ584_10590) tcyN 2154859..2155611 (-) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  GQ584_RS10725 (GQ584_10595) tcyL 2155608..2156276 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  GQ584_RS10730 (GQ584_10600) dcyD 2156291..2157277 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=357116 GQ584_RS10700 WP_000611328.1 2152500..2153156(-) (letA) [Escherichia coli NC101]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=357116 GQ584_RS10700 WP_000611328.1 2152500..2153156(-) (letA) [Escherichia coli NC101]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482