Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   GQF95_RS12540 Genome accession   NZ_CP047010
Coordinates   2573743..2574399 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain 19-5     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2568743..2579399
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GQF95_RS12510 (GQF95_12470) - 2569874..2570614 (+) 741 WP_072663995.1 hypothetical protein -
  GQF95_RS12530 (GQF95_12490) pgsA 2571309..2571857 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  GQF95_RS12535 (GQF95_12495) uvrC 2571914..2573746 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  GQF95_RS12540 (GQF95_12500) letA 2573743..2574399 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  GQF95_RS26340 - 2574541..2574612 (+) 72 Protein_2478 transcriptional regulator -
  GQF95_RS12545 (GQF95_12505) yecU 2574695..2574871 (+) 177 WP_147723667.1 protein YecU -
  GQF95_RS12550 (GQF95_12510) yecF 2574858..2575082 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  GQF95_RS12555 (GQF95_12515) sdiA 2575150..2575872 (-) 723 WP_001154268.1 transcriptional regulator SdiA -
  GQF95_RS12560 (GQF95_12520) tcyN 2576102..2576854 (-) 753 WP_023356451.1 L-cystine ABC transporter ATP-binding protein TcyN -
  GQF95_RS12565 (GQF95_12525) tcyL 2576851..2577519 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  GQF95_RS12570 (GQF95_12530) dcyD 2577534..2578520 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=356857 GQF95_RS12540 WP_000611328.1 2573743..2574399(-) (letA) [Escherichia coli strain 19-5]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=356857 GQF95_RS12540 WP_000611328.1 2573743..2574399(-) (letA) [Escherichia coli strain 19-5]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482