Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   HNEAP_RS11315 Genome accession   NC_013422
Coordinates   2437293..2438774 (-) Length   493 a.a.
NCBI ID   WP_012825114.1    Uniprot ID   D0KWW3
Organism   Halothiobacillus neapolitanus c2     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2432293..2443774
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HNEAP_RS11285 (Hneap_2262) - 2432660..2432875 (-) 216 WP_012825107.1 CsbD family protein -
  HNEAP_RS11290 (Hneap_2263) - 2432878..2433162 (-) 285 WP_133484713.1 hypothetical protein -
  HNEAP_RS12755 (Hneap_2264) - 2433295..2433441 (+) 147 WP_012825109.1 lmo0937 family membrane protein -
  HNEAP_RS11295 (Hneap_2265) murI 2433455..2434321 (-) 867 WP_012825110.1 glutamate racemase -
  HNEAP_RS11300 (Hneap_2266) phoB 2434506..2435198 (+) 693 WP_012825111.1 phosphate regulon transcriptional regulator PhoB -
  HNEAP_RS11305 (Hneap_2267) phoR 2435205..2436623 (+) 1419 WP_012825112.1 phosphate regulon sensor histidine kinase PhoR -
  HNEAP_RS11310 (Hneap_2268) - 2436661..2437035 (-) 375 WP_243726360.1 SCP-2 sterol transfer family protein -
  HNEAP_RS11315 (Hneap_2269) pilR 2437293..2438774 (-) 1482 WP_012825114.1 sigma-54-dependent transcriptional regulator Regulator
  HNEAP_RS11320 (Hneap_2270) - 2438803..2440449 (-) 1647 WP_012825115.1 sensor histidine kinase -
  HNEAP_RS11325 - 2440486..2440725 (-) 240 WP_041600448.1 PP0621 family protein -
  HNEAP_RS11330 (Hneap_2272) msrA 2441017..2442273 (-) 1257 WP_012825117.1 peptide-methionine (S)-S-oxide reductase MsrA -
  HNEAP_RS11335 (Hneap_2273) - 2442486..2443373 (-) 888 WP_012825118.1 glycosyltransferase family 2 protein -

Sequence

Protein


Download         Length: 493 a.a.        Molecular weight: 53368.73 Da        Isoelectric Point: 6.0354

>NTDB_id=35535 HNEAP_RS11315 WP_012825114.1 2437293..2438774(-) (pilR) [Halothiobacillus neapolitanus c2]
MTACLIVDDELDIRTLIALSLRREGVTCHLAADLASARAQLAESGHTLSFCLTDMRLPDGDGLDLLDEIRQRFPDLPVAV
ITAHGQVDAAVRALKAGAFDFVSKPIEQLVLKRLLRDALKARTLDSAPDQSSQHALGSSASGQDAAPREGPFDAGPNAAD
MGQGAAKSPLIGPSRAMQMLRETIAKVARSQAPVFICGESGTGKELVARQIHELSGRADGPFIPVNCGAIPAELIESELF
GHKKGAFTGAHQAHEGLFRAAEGGSLFLDEVADLPLGLQVKLLRAIQERKVRPVGEYAEVPIDVRIISASHQDLNAAVRD
GRFRHDLFYRLNVIELRVPPLRARLEDLPALCAHILGKLAEREHRPPPHLTPEALSWLAQQSFEGNVRGLENLLERAIAL
TEGDLLGVSALTDFPGDNSFDSSAEQNGLHLGSPPDVKSTWGATPPSSALEAEEQRQVLSALEMTRWNRSEAARRLGLSL
RQLRYRLAKWGVE

Nucleotide


Download         Length: 1482 bp        

>NTDB_id=35535 HNEAP_RS11315 WP_012825114.1 2437293..2438774(-) (pilR) [Halothiobacillus neapolitanus c2]
ATGACCGCTTGCCTGATCGTTGATGATGAACTGGATATTCGCACCCTCATTGCCTTGTCGTTGCGCCGTGAAGGCGTGAC
TTGCCATCTGGCCGCCGATCTGGCCAGCGCGCGCGCTCAGTTGGCAGAGTCGGGCCACACGTTAAGTTTTTGTTTGACCG
ACATGCGCTTGCCCGATGGCGATGGGCTTGATCTGCTCGATGAGATTCGCCAGCGGTTTCCCGATTTGCCTGTCGCGGTA
ATTACGGCGCATGGGCAAGTGGACGCGGCCGTGCGCGCCCTCAAGGCAGGCGCATTCGATTTTGTTTCCAAACCGATCGA
GCAATTGGTGCTCAAGCGCCTGTTGCGCGATGCATTAAAGGCCAGAACACTTGATTCGGCTCCTGATCAGTCATCTCAGC
ATGCGTTAGGGTCGAGCGCATCCGGGCAAGACGCGGCGCCCAGAGAAGGTCCTTTCGATGCTGGCCCGAACGCGGCTGAC
ATGGGGCAGGGCGCGGCCAAATCACCATTGATTGGCCCGTCGCGTGCCATGCAGATGCTGCGTGAAACCATTGCCAAGGT
GGCGCGATCTCAGGCACCGGTGTTCATCTGCGGCGAGTCGGGCACAGGCAAAGAGCTGGTGGCGCGACAGATCCATGAAC
TCAGTGGTCGGGCCGACGGCCCTTTCATTCCGGTCAACTGCGGTGCCATTCCGGCTGAATTGATCGAGAGCGAGTTGTTC
GGCCACAAGAAAGGTGCTTTCACGGGCGCGCATCAGGCGCATGAAGGGCTTTTTCGTGCGGCGGAAGGCGGGAGCCTGTT
TCTGGACGAAGTGGCCGATTTGCCGCTGGGTTTGCAGGTCAAGTTGCTGCGCGCCATTCAGGAGCGCAAGGTGCGCCCGG
TGGGTGAGTATGCCGAAGTCCCCATTGATGTGCGCATCATCTCCGCATCGCATCAGGACTTGAATGCGGCGGTGCGCGAT
GGGCGCTTCCGGCACGATTTGTTTTACCGCCTCAATGTGATCGAGCTACGCGTGCCGCCGCTGCGCGCGCGCTTGGAAGA
TCTCCCCGCGCTCTGTGCCCATATCCTGGGCAAGCTGGCTGAGCGCGAGCACCGCCCACCCCCGCACCTCACTCCGGAGG
CATTGAGTTGGCTGGCCCAGCAGTCATTTGAGGGGAATGTTCGGGGATTGGAGAATCTACTGGAGCGGGCCATCGCGTTG
ACCGAGGGTGATCTGCTTGGCGTTTCCGCACTGACCGATTTCCCGGGGGACAATTCGTTTGACTCTTCGGCCGAGCAGAA
TGGTCTTCATTTGGGTTCACCACCGGACGTCAAATCGACTTGGGGCGCTACGCCGCCGAGCAGCGCATTGGAAGCCGAAG
AGCAGCGGCAGGTGCTCAGCGCGCTGGAAATGACCCGGTGGAATCGCAGCGAGGCGGCCCGACGTTTGGGGTTGAGCTTG
CGGCAACTCCGCTATCGGCTGGCCAAATGGGGCGTCGAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory protein, Fis family (HTH_8)

(450-490)

Sigma-54 interaction domain (Sigma54_activat)

(170-336)

Response regulator receiver domain (Response_reg)

(5-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB D0KWW3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

49.593

99.797

0.495
  pilR Acinetobacter baumannii strain A118

47.791

100

0.483

Multiple sequence alignment