Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   GO596_RS08655 Genome accession   NZ_CP046628
Coordinates   1745506..1747293 (-) Length   595 a.a.
NCBI ID   WP_157339614.1    Uniprot ID   -
Organism   Streptococcus equinus strain CNU 77-23     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1740506..1752293
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GO596_RS08635 (GO596_08635) - 1740730..1741314 (-) 585 WP_157339611.1 uracil-DNA glycosylase family protein -
  GO596_RS08640 (GO596_08640) pepV 1741383..1742789 (-) 1407 WP_157339612.1 dipeptidase PepV -
  GO596_RS08645 (GO596_08645) - 1742953..1743555 (-) 603 WP_021142121.1 nitroreductase family protein -
  GO596_RS08650 (GO596_08650) - 1743678..1745408 (-) 1731 WP_157339613.1 hypothetical protein -
  GO596_RS08655 (GO596_08655) uvrC 1745506..1747293 (-) 1788 WP_157339614.1 excinuclease ABC subunit UvrC Machinery gene
  GO596_RS08660 (GO596_08660) - 1747521..1748546 (-) 1026 WP_157339615.1 YeiH family protein -
  GO596_RS08665 (GO596_08665) - 1748653..1749519 (+) 867 WP_157339616.1 LysR family transcriptional regulator -
  GO596_RS08670 (GO596_08670) - 1749600..1750271 (+) 672 WP_157339617.1 Crp/Fnr family transcriptional regulator -
  GO596_RS08675 (GO596_08675) - 1750321..1750650 (-) 330 WP_074669358.1 potassium channel family protein -
  GO596_RS08680 (GO596_08680) - 1750721..1751407 (-) 687 WP_157339618.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 595 a.a.        Molecular weight: 68653.28 Da        Isoelectric Point: 9.2920

>NTDB_id=354026 GO596_RS08655 WP_157339614.1 1745506..1747293(-) (uvrC) [Streptococcus equinus strain CNU 77-23]
MNELIKHKLELLPDSPGCYIHKDKNGKIIYVGKAKNLKNRVRSYFHGSHNTKTELLVSEIEDFEYIVTGSNTEALLLEIN
LIQENMPKYNIKLKDDKSYPFIKITVNEQYPRLMITRQIKKDGAMYFGPYPDSGAATEIKRLLDRIFPFKKCTNPANKVC
FYYHLGQCKAHTICHVDHDYFVEMAQDVKNFLDGKDNKIVDGLKDKMQKASDMMEFERAAEYRDLLQAISTLRTKQRVMN
QDMMDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNMFPYYNDPEEDFLTYVGQFYRDSKHFVPKEVFIPQDIDEELVKA
VVDTKVIKPQRGEKKQLVNLATKNARVSLQQKFDLLEKDIRKTHGAIENIGELLNIPKPVRIEAFDNSNIQGTSPVAGMV
AFVNGKPSKKDYRKFKIKTVVGPDDYASMREVIYRRYSRVMKDGLTPPDLIIIDGGQGQVNVARDVIENKLGLDIPIVGL
QKNDKHQTHELLFGDPLEVVELPRNSEEFFLLQRIQDEVHRFAITFHRQLRSKNSFSSKLDGIAGLGPKRKQLLMKHFKS
LPNIQKADVDDIINCGVPRNVAIAVKEKLSEEKKG

Nucleotide


Download         Length: 1788 bp        

>NTDB_id=354026 GO596_RS08655 WP_157339614.1 1745506..1747293(-) (uvrC) [Streptococcus equinus strain CNU 77-23]
ATGAATGAACTGATTAAACACAAATTGGAATTGCTTCCAGATAGCCCTGGTTGCTATATCCATAAAGATAAAAACGGCAA
AATTATCTATGTCGGAAAGGCAAAAAATCTCAAAAATCGTGTGCGCAGCTATTTTCACGGTAGCCACAATACCAAGACAG
AACTCTTGGTTTCTGAAATTGAAGATTTTGAATACATTGTTACTGGGTCAAATACAGAAGCCCTTCTTCTTGAAATCAAT
CTGATTCAAGAAAACATGCCAAAGTATAACATCAAGCTAAAAGATGACAAATCTTACCCATTCATCAAAATCACGGTGAA
TGAGCAGTACCCACGCTTGATGATTACCCGCCAAATCAAAAAAGATGGTGCTATGTATTTTGGACCATACCCAGATTCTG
GTGCTGCGACAGAAATCAAACGTCTGCTAGACCGCATTTTCCCATTCAAAAAATGTACAAATCCTGCTAACAAGGTTTGT
TTTTATTACCATTTGGGGCAATGTAAAGCTCATACAATTTGTCATGTTGACCATGATTATTTTGTTGAAATGGCGCAAGA
CGTCAAGAATTTTCTTGATGGCAAAGACAATAAAATCGTCGATGGCTTGAAAGACAAAATGCAAAAAGCGTCAGACATGA
TGGAATTTGAACGTGCGGCAGAATACCGTGATTTATTGCAAGCTATCTCAACACTTCGTACCAAACAACGTGTCATGAAC
CAAGATATGATGGACCGTGATATTTTTGGTTATTATGTCGACAAAGGTTGGATGTGTGTGCAGGTATTCTTTGTTCGCCA
AGGAAAACTCATCCAACGTGATGTCAATATGTTCCCGTATTACAATGACCCAGAAGAAGATTTCTTGACCTATGTCGGAC
AATTTTACCGAGACAGCAAGCATTTTGTGCCAAAAGAAGTCTTTATTCCTCAGGACATTGACGAAGAATTAGTTAAAGCA
GTTGTTGATACCAAAGTCATCAAACCACAACGTGGTGAGAAGAAGCAGCTGGTAAATCTCGCGACAAAAAACGCGCGTGT
CAGCTTACAACAAAAATTTGACCTGCTAGAAAAAGATATTCGCAAAACGCACGGCGCTATTGAAAATATCGGTGAATTGC
TCAATATTCCAAAACCAGTGCGCATTGAAGCCTTTGATAACTCAAATATTCAAGGAACAAGCCCAGTTGCGGGGATGGTT
GCCTTTGTAAATGGAAAACCAAGTAAGAAAGATTACCGTAAATTTAAAATTAAAACTGTTGTCGGCCCAGACGACTATGC
CAGCATGCGTGAAGTCATTTATCGTAGATACAGTCGAGTCATGAAAGACGGTCTAACTCCGCCAGATTTGATTATCATCG
ATGGTGGTCAAGGTCAGGTTAATGTTGCGCGCGATGTCATTGAAAATAAACTTGGACTCGATATTCCAATCGTTGGTCTG
CAAAAAAATGACAAGCACCAAACGCACGAATTGCTCTTTGGTGACCCATTAGAAGTGGTCGAATTGCCACGAAACTCTGA
AGAATTCTTCCTCTTACAGCGTATTCAAGATGAAGTTCACAGATTTGCCATTACTTTCCACCGTCAACTCCGTTCTAAAA
ATTCATTCTCATCAAAACTCGATGGCATTGCTGGGCTTGGTCCAAAGCGTAAGCAATTACTCATGAAACACTTCAAGAGC
TTGCCAAATATTCAAAAAGCAGACGTGGACGACATTATCAACTGTGGCGTCCCACGAAACGTTGCCATTGCTGTGAAAGA
AAAACTAAGTGAGGAGAAGAAAGGGTAA

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(17-90)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-524)

UvrB/uvrC motif (UVR)

(199-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

79.153

99.16

0.785
  uvrC Streptococcus pneumoniae R6

78.983

99.16

0.783
  uvrC Streptococcus pneumoniae D39

78.983

99.16

0.783