Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   GO596_RS00705 Genome accession   NZ_CP046628
Coordinates   138416..139060 (-) Length   214 a.a.
NCBI ID   WP_024344653.1    Uniprot ID   -
Organism   Streptococcus equinus strain CNU 77-23     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 133416..144060
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GO596_RS00680 (GO596_00680) comFA/cflA 133460..134758 (-) 1299 WP_157339042.1 DEAD/DEAH box helicase Machinery gene
  GO596_RS00685 (GO596_00685) - 134813..135439 (+) 627 WP_157339043.1 YigZ family protein -
  GO596_RS00690 (GO596_00690) cysK 135537..136466 (+) 930 WP_021141798.1 cysteine synthase A -
  GO596_RS00695 (GO596_00695) - 136536..136892 (-) 357 WP_027968108.1 S1 RNA-binding domain-containing protein -
  GO596_RS00700 (GO596_00700) - 136892..138292 (-) 1401 WP_029876003.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  GO596_RS00705 (GO596_00705) vraR 138416..139060 (-) 645 WP_024344653.1 response regulator transcription factor Regulator
  GO596_RS00710 (GO596_00710) - 139044..140069 (-) 1026 WP_157339044.1 sensor histidine kinase -
  GO596_RS00715 (GO596_00715) liaF 140066..140761 (-) 696 WP_027968110.1 cell wall-active antibiotics response protein LiaF -
  GO596_RS00720 (GO596_00720) pknB 140905..142779 (-) 1875 WP_157339045.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  GO596_RS00725 (GO596_00725) - 142779..143516 (-) 738 WP_157339046.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 23992.85 Da        Isoelectric Point: 5.1944

>NTDB_id=353939 GO596_RS00705 WP_024344653.1 138416..139060(-) (vraR) [Streptococcus equinus strain CNU 77-23]
MTQKIRVILVDDHEMVRLGLKSFFNLQPDVEVVGEAGNGIDGIKLALELKPDVVVMDLVMPEMSGVEATLKLLKEWKEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNAIHKVARGDLAIETEVDKKIKAHDQKPELHEDLTARERDILKLL
AKGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQAVVYAFKHHLVPQDEE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=353939 GO596_RS00705 WP_024344653.1 138416..139060(-) (vraR) [Streptococcus equinus strain CNU 77-23]
ATGACCCAGAAAATTAGAGTTATCCTAGTTGATGATCATGAAATGGTACGTTTAGGGCTGAAAAGTTTCTTTAATTTGCA
GCCAGACGTTGAAGTTGTCGGTGAAGCTGGAAATGGTATTGATGGGATAAAATTAGCCTTAGAGTTAAAACCAGATGTTG
TTGTTATGGATTTGGTAATGCCAGAGATGAGTGGTGTTGAAGCGACATTGAAGCTTTTAAAAGAGTGGAAAGAAGCCAAA
ATTTTAGTTTTGACATCATACCTTGATAATGAAAAAATTTATCCAGTTATTGAAGCTGGTGCCAAAGGTTACATGCTAAA
AACATCTAGTGCAGCTGAGATTTTAAATGCTATTCATAAAGTTGCGCGTGGTGATTTGGCGATTGAGACAGAAGTTGATA
AAAAAATCAAAGCGCACGATCAAAAACCAGAATTGCATGAGGATCTTACAGCGCGTGAACGAGATATTTTGAAACTTTTG
GCAAAAGGTTACGATAATCAGACTATTGCTGATGAGTTATTTATTTCTCTGAAAACCGTGAAGACACACGTGTCAAATAT
TTTAGCGAAGCTAGAAGTTGACGACCGTACTCAAGCTGTTGTCTATGCCTTTAAGCATCATTTAGTTCCGCAAGATGAGG
AATAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-203)

Response regulator receiver domain (Response_reg)

(7-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

51.456

96.262

0.495
  degU Bacillus subtilis subsp. subtilis str. 168

37.5

100

0.393

Multiple sequence alignment