Detailed information NTG0353665

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: GO004_RS20705
• Genome accession: NZ_CP046591
• Coordinates: 4001301..4002563 (+)
• Length: 420 a.a.
• NCBI ID: WP_003229613.1
• Uniprot ID: A0ABU0V489
• Organism: Bacillus subtilis strain R31
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 3996301..4007563

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GO004_RS20685 (GO004_20700)	leuC	3996374..3997792 (+)	1419	WP_003229604.1	3-isopropylmalate dehydratase large subunit	-
GO004_RS20690 (GO004_20705)	leuD	3997805..3998404 (+)	600	WP_003229606.1	3-isopropylmalate dehydratase small subunit	-
GO004_RS20695 (GO004_20710)	ddcA	3998523..3999527 (+)	1005	WP_003229609.1	DNA damage checkpoint antagonist DdcA	-
GO004_RS20700 (GO004_20715)	tig	3999755..4001029 (+)	1275	WP_003229611.1	trigger factor	-
GO004_RS20705 (GO004_20720)	clpX	4001301..4002563 (+)	1263	WP_003229613.1	ATP-dependent protease ATP-binding subunit ClpX	Regulator
GO004_RS20710 (GO004_20725)	lonB	4002715..4004373 (+)	1659	WP_004398923.1	ATP-dependent protease LonB	-
GO004_RS20715 (GO004_20730)	lon	4004554..4006878 (+)	2325	WP_003229618.1	endopeptidase La	-
GO004_RS20720 (GO004_20735)	yihA	4006875..4007462 (+)	588	WP_003229621.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-

Sequence

Protein

• Length: 420 a.a.
• Molecular weight: 46350.22 Da
• Isoelectric Point: 4.5879

>NTDB_id=353665 GO004_RS20705 WP_003229613.1 4001301..4002563(+) (clpX) [Bacillus subtilis strain R31]
MFKFNEEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEIVEEELGTEEEVEFKDVPKPQEIREILNEYVIGQDQ
AKKSLAVAVYNHYKRINSNSKVDDVELSKSNISLIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILL
KLIQAADYDVEKAEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNI
LFICGGAFDGIEQIIKRRLGQKVIGFGADNKAADLEKEDLLSKVLPEDLLRFGLIPEFIGRLPVIASLEKLDEEALVAIL
TKPKNALVKQFKKMLELDNVELEFEEEALSEIAKKAIERKTGARGLRSIIEGIMLDVMFELPSRDDIEKCVITGATVTHG
EPPRLLLKDGTEVSQDKTSA

Nucleotide

• Length: 1263 bp

>NTDB_id=353665 GO004_RS20705 WP_003229613.1 4001301..4002563(+) (clpX) [Bacillus subtilis strain R31]
ATGTTTAAATTTAACGAGGAAAAAGGACAATTAAAATGCTCGTTCTGTGGAAAAACACAAGATCAGGTTCGTAAGCTTGT
AGCTGGACCTGGTGTATATATATGTGACGAATGTATCGAACTCTGCACTGAAATTGTAGAGGAAGAACTCGGAACAGAAG
AAGAAGTAGAATTTAAAGACGTACCAAAGCCTCAGGAAATTCGCGAAATTTTGAATGAATATGTCATCGGCCAAGATCAA
GCGAAGAAATCACTTGCTGTTGCTGTGTATAACCACTATAAGCGCATTAACTCCAACAGCAAAGTTGATGATGTTGAGCT
TTCAAAAAGTAATATTTCATTAATCGGCCCTACGGGAAGCGGTAAAACCCTTCTGGCGCAAACATTGGCTCGCATTTTAA
ATGTGCCGTTTGCGATTGCGGACGCTACATCTTTGACTGAAGCTGGATACGTGGGTGAAGATGTAGAGAATATTCTCTTG
AAGCTCATCCAAGCTGCTGATTATGATGTGGAAAAAGCCGAAAAAGGCATTATCTATATTGATGAAATCGATAAAGTGGC
TAGAAAATCTGAAAACCCGTCTATCACACGTGATGTGTCAGGTGAGGGTGTACAGCAGGCATTGCTTAAAATTCTTGAGG
GTACAGTGGCAAGCGTACCGCCTCAAGGTGGACGTAAGCATCCTCATCAAGAATTCATTCAAATTGACACAACAAATATT
TTGTTCATTTGCGGCGGAGCTTTCGATGGTATCGAACAAATCATCAAACGCCGTTTAGGCCAAAAAGTGATTGGATTCGG
TGCCGACAATAAAGCTGCTGATCTTGAGAAAGAAGATCTTCTTTCAAAAGTGCTTCCAGAAGATTTGCTCCGTTTCGGGT
TAATTCCTGAATTTATCGGACGTCTTCCGGTTATTGCAAGCCTTGAAAAGCTTGACGAAGAAGCATTGGTTGCGATCTTA
ACAAAACCGAAAAACGCTCTTGTTAAGCAATTCAAGAAAATGCTTGAGCTTGACAACGTTGAGCTTGAGTTTGAAGAAGA
AGCGCTTTCTGAAATTGCTAAAAAAGCAATTGAACGCAAGACTGGAGCACGCGGACTCCGTTCTATCATTGAAGGCATCA
TGCTTGATGTGATGTTTGAGCTGCCTTCTCGTGATGACATTGAAAAATGTGTAATCACCGGGGCAACTGTGACACACGGA
GAGCCTCCTCGCCTCTTATTAAAAGACGGCACTGAGGTAAGCCAAGATAAAACATCTGCATAA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (109-305)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (311-389)

• ClpX C4-type zinc finger (zf-C4_ClpX) (11-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	68.01	94.524	0.643
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	60.506	94.048	0.569