Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   GO004_RS05035 Genome accession   NZ_CP046591
Coordinates   932860..934743 (-) Length   627 a.a.
NCBI ID   WP_088467663.1    Uniprot ID   -
Organism   Bacillus subtilis strain R31     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 927860..939743
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GO004_RS05005 (GO004_04975) fabD 928476..929342 (-) 867 WP_038428987.1 ACP S-malonyltransferase -
  GO004_RS05010 (GO004_04980) - 929339..929605 (-) 267 WP_134818945.1 hypothetical protein -
  GO004_RS05015 (GO004_04985) pksB 929716..930393 (-) 678 WP_088467664.1 MBL fold metallo-hydrolase -
  GO004_RS05020 (GO004_04990) pksA 930583..931200 (-) 618 WP_003231827.1 TetR/AcrR family transcriptional regulator -
  GO004_RS05025 (GO004_04995) - 931321..931878 (+) 558 WP_033883746.1 hypothetical protein -
  GO004_RS05030 (GO004_05000) ymzD 932006..932461 (+) 456 WP_088467694.1 regulatory YrvL family protein -
  GO004_RS05035 (GO004_05005) hexB 932860..934743 (-) 1884 WP_088467663.1 DNA mismatch repair endonuclease MutL Machinery gene
  GO004_RS05040 (GO004_05010) hexA 934759..937335 (-) 2577 WP_003231832.1 DNA mismatch repair protein MutS Machinery gene
  GO004_RS05045 (GO004_05015) cotE 937468..938013 (-) 546 WP_003231833.1 outer spore coat protein CotE -
  GO004_RS05050 (GO004_05020) ymcA 938274..938705 (-) 432 WP_003231834.1 regulatory iron-sulfur-containing complex subunit RicA Regulator

Sequence

Protein


Download         Length: 627 a.a.        Molecular weight: 70542.43 Da        Isoelectric Point: 5.6018

>NTDB_id=353552 GO004_RS05035 WP_088467663.1 932860..934743(-) (hexB) [Bacillus subtilis strain R31]
MAKVIQLSDELSNKIAAGEVVERPASIVKELVENAIDADSTVIEIDIEEAGLASIRVLDNGEGMENEDCKRAFRRHATSK
IKDENDLFRVRTLGFRGEALPSIASVSHLEITTSTGEGAGTKLVLQGGNIISESRSSSRKGTEIVVSNLFFNTPARLKYM
KTVHTELGNITDVVNRIALAHPEVSIRLRHHGKNLLQTNGNGDVRHVLAAIYGTAVAKKMLPLHVSSLDFEVKGYIALPE
ITRASRNYMSSVVNGRYIKNFPLVKAVHEGYHTLLPIGRHPITFIEITMDPILVDVNVHPSKLEVRLSKETELHDLIRDG
IKDVFKQQQLIPSAQLPKKSAPAIKNEQQFITFDEKPPEKKVSEKSTASSYSPMKLSSVVKEPVDAEEELPPLQFDAPPI
VDQEQTLEVSDISEELPETFEQECHEEQQQPASERVPIMYPIGQMHGTYILAQNENGLYIIDQHAAQERIKYEYFREKVG
EVEPEVQEMIVPLTFHYSTNEALIIEQHKQELESVGVFLESFGSNSYIVRCHPAWFPKGEEAELIEEIIQQVLDSKNIDI
KKLREEAAIMMSCKGSIKANRHLRNDEIKALLDDLRSTSDPFTCPHGRPIIIHHSTYEMEKMFKRVM

Nucleotide


Download         Length: 1884 bp        

>NTDB_id=353552 GO004_RS05035 WP_088467663.1 932860..934743(-) (hexB) [Bacillus subtilis strain R31]
GTGGCAAAAGTCATCCAGCTGTCAGATGAGCTTTCAAATAAAATAGCGGCGGGCGAGGTTGTGGAACGGCCCGCCTCAAT
CGTCAAAGAATTGGTGGAAAATGCGATCGACGCTGACAGCACAGTCATTGAAATCGATATTGAGGAAGCAGGCCTTGCAT
CCATTCGGGTCTTGGATAACGGCGAAGGAATGGAGAATGAAGATTGCAAGCGAGCTTTCCGCCGCCACGCAACGAGTAAA
ATAAAAGATGAAAATGATTTATTCAGGGTGAGAACGCTCGGTTTCAGGGGAGAAGCCCTGCCGAGTATCGCGTCAGTCTC
TCATCTGGAGATTACAACAAGCACTGGTGAAGGAGCTGGGACGAAGCTCGTCCTCCAAGGAGGAAACATCATTTCCGAAT
CGCGTTCCTCAAGCAGGAAGGGAACTGAAATTGTCGTTTCCAACCTGTTTTTTAACACACCGGCCCGTTTGAAATATATG
AAAACCGTTCATACAGAGCTTGGAAACATTACGGATGTGGTTAACCGTATTGCTCTGGCGCATCCAGAGGTATCGATCCG
CCTGCGCCATCATGGGAAAAACCTGCTTCAAACGAACGGAAACGGAGATGTGCGCCATGTACTGGCAGCGATTTACGGCA
CGGCTGTCGCCAAAAAAATGCTTCCGCTGCATGTGAGCTCCTTGGATTTTGAAGTAAAGGGATATATCGCCCTCCCAGAG
ATTACACGGGCGTCGAGGAACTATATGTCGTCTGTGGTCAATGGCCGTTACATTAAAAATTTCCCGCTCGTCAAAGCGGT
TCATGAAGGCTATCATACGCTTCTGCCGATCGGACGCCATCCGATTACTTTTATAGAAATTACGATGGACCCGATTTTAG
TCGATGTCAACGTGCATCCATCGAAGCTTGAGGTCCGGCTCAGCAAGGAAACAGAGCTTCATGACTTAATACGTGACGGA
ATTAAAGATGTGTTTAAACAGCAGCAGCTGATTCCGAGTGCCCAGCTCCCGAAAAAATCAGCACCTGCCATCAAAAATGA
GCAGCAGTTCATAACCTTTGATGAAAAGCCTCCGGAAAAAAAAGTTTCGGAAAAATCGACTGCGTCATCTTATTCACCAA
TGAAGCTCAGCTCAGTCGTGAAAGAGCCGGTTGATGCGGAGGAAGAATTGCCTCCTCTCCAATTTGATGCTCCACCTATC
GTTGATCAGGAACAAACCCTTGAGGTGTCCGATATTTCAGAAGAACTGCCTGAAACATTTGAGCAGGAATGCCATGAGGA
ACAGCAGCAGCCAGCGTCTGAGCGGGTTCCGATTATGTACCCGATCGGCCAGATGCACGGGACTTATATATTGGCACAAA
ACGAAAACGGCCTATATATTATCGACCAGCACGCCGCCCAAGAACGTATTAAATATGAGTACTTCCGTGAAAAGGTGGGG
GAGGTTGAGCCTGAGGTGCAGGAGATGATTGTACCGCTGACGTTCCACTACTCCACAAATGAGGCTTTGATTATTGAACA
GCACAAACAAGAGCTCGAAAGCGTCGGTGTCTTTTTAGAGTCATTCGGCTCTAACAGTTACATCGTCCGCTGCCACCCAG
CCTGGTTTCCAAAGGGAGAAGAAGCAGAGCTTATAGAAGAAATCATTCAGCAGGTGCTCGACTCCAAAAATATAGATATT
AAAAAACTCCGCGAGGAAGCGGCGATTATGATGAGCTGCAAAGGCTCCATCAAAGCAAATCGCCACCTCAGAAACGATGA
AATCAAAGCGCTTCTGGACGACCTCCGAAGCACATCAGACCCATTTACATGCCCGCACGGCCGCCCGATCATCATTCACC
ACTCGACATATGAGATGGAAAAGATGTTCAAACGCGTGATGTAG

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-324)

MutL C terminal dimerisation domain (MutL_C)

(442-583)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(26-124)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

45.201

100

0.466

Multiple sequence alignment