Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   GOM47_RS08825 Genome accession   NZ_CP046524
Coordinates   1764839..1767670 (-) Length   943 a.a.
NCBI ID   WP_235081286.1    Uniprot ID   -
Organism   Streptococcus oralis strain SOT     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1759839..1772670
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM47_RS08810 (GOM47_08815) spx 1760189..1760587 (-) 399 WP_000591165.1 transcriptional regulator Spx -
  GOM47_RS08815 (GOM47_08820) mgtA 1760722..1763382 (-) 2661 WP_235080562.1 magnesium-translocating P-type ATPase -
  GOM47_RS08820 (GOM47_08825) - 1763785..1764846 (-) 1062 WP_235080563.1 M24 family metallopeptidase -
  GOM47_RS08825 (GOM47_08830) uvrA 1764839..1767670 (-) 2832 WP_235081286.1 excinuclease ABC subunit UvrA Machinery gene
  GOM47_RS08830 (GOM47_08835) - 1767807..1768751 (+) 945 WP_000815625.1 magnesium transporter CorA family protein -
  GOM47_RS08835 (GOM47_08840) - 1768763..1769440 (+) 678 WP_235080564.1 DUF1129 domain-containing protein -
  GOM47_RS08840 (GOM47_08845) - 1769578..1770615 (+) 1038 WP_235080565.1 S66 peptidase family protein -
  GOM47_RS08845 (GOM47_08850) - 1770661..1771344 (-) 684 WP_235081287.1 CPBP family intramembrane glutamic endopeptidase -
  GOM47_RS08850 (GOM47_08855) - 1771345..1771905 (-) 561 WP_235080566.1 DNA-3-methyladenine glycosylase I -
  GOM47_RS08855 (GOM47_08860) ruvA 1771915..1772508 (-) 594 WP_235080567.1 Holliday junction branch migration protein RuvA Machinery gene

Sequence

Protein


Download         Length: 943 a.a.        Molecular weight: 104072.11 Da        Isoelectric Point: 6.3291

>NTDB_id=352853 GOM47_RS08825 WP_235081286.1 1764839..1767670(-) (uvrA) [Streptococcus oralis strain SOT]
MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGL
SPAISIDQKTTSKNPRSTVGTTTEINDYLRLLYARVGTPYCINGHGAIKASSVEQIVDKVLELPERQRLQILAPVIRKKK
GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRLFDSIEAALRIAEGYVIIDTMDD
SELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCSECDGLGIKLEVDTDLVVPDASKTLREGALAPWNPISSNYYPNML
EQAMTAFGVDMDKPFEDLLEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVVNNIKRRYHETNSDYTRTQMRLYM
NELTCGTCHGYRLNDQALSVRVGGEQGLHIGEISDLSIADHLELVSQLTLSENEAIIARPILKEIKDRLTFLNNVGLNYL
TLSRSAGTLSGGESQRIRLATQIGSNLSGVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLI
DVGPGAGAFGGEIVAAGTPKQVARNSKSITGQYLSGKRAIPVPAERRAGNGRFIEVTGARENNLQNITARFPLGKFIAVT
GVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHVDRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNE
AKIRGYKKGRFSFNVKGGRCEACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVEFF
QHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYILDEPTTGLHTEDIARLLKVLARFVD
DGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGTIIATGTPEEVAANEASYTGHYLKGKLHHE

Nucleotide


Download         Length: 2832 bp        

>NTDB_id=352853 GOM47_RS08825 WP_235081286.1 1764839..1767670(-) (uvrA) [Streptococcus oralis strain SOT]
ATGCAAGATAAGATTGTGATTCATGGGGCACGCGCCCATAATTTAAAAAATATCGATGTGGAGATTCCGCGTGACAAGCT
GGTCGTGGTTACGGGTTTGTCGGGTTCTGGCAAGTCCAGTCTGGCCTTTGATACCCTCTATGCTGAGGGACAAAGGCGCT
ATGTAGAGAGTCTATCAGCCTATGCTCGTCAGTTTTTGGGCAACATGGAAAAACCAGATGTAGATGCCATTGACGGCCTC
AGCCCAGCTATTTCCATCGACCAGAAAACTACCAGTAAAAACCCGCGCTCGACCGTGGGAACAACAACTGAAATCAATGA
CTATCTGCGTCTCCTCTACGCACGTGTGGGGACGCCGTACTGTATTAACGGGCATGGGGCAATCAAGGCCTCTTCTGTTG
AGCAAATCGTTGATAAGGTCTTAGAATTGCCAGAACGCCAACGTCTGCAAATTTTAGCTCCTGTCATTCGTAAGAAAAAA
GGACAACATAAGAGTGTCATTGAAAAGGTTCAGAAAGACGGTTATGTCCGCGTCCGAGTGGATGGGGAGGTCTATGATGT
GACCGAAGTGCCAGAGTTGTCCAAGAGCAAGCAACACAATATTGATGTCGTGGTTGACCGTATTGTCATCAAGGAGGGCA
TTCGTAGCCGTCTCTTTGATTCCATTGAGGCTGCCCTTCGTATCGCAGAAGGCTATGTGATTATCGACACTATGGACGAT
TCTGAGCTGCTCTTCTCTGAGCATTATGCCTGTCCAGTTTGTGGTTTTACCGTACCAGAGTTAGAGCCTCGTCTCTTCTC
CTTTAATGCTCCTTTTGGTTCTTGTAGTGAGTGTGACGGTTTGGGCATCAAGCTGGAGGTGGATACTGACTTGGTAGTGC
CAGATGCCAGCAAAACGCTACGTGAGGGGGCTTTGGCACCTTGGAATCCTATCTCATCTAACTACTATCCAAATATGCTA
GAGCAGGCCATGACAGCCTTTGGAGTGGATATGGATAAGCCCTTTGAGGACTTGTTAGAAGAAGATAAGAACTTGATTCT
CTACGGCTCGGATGGCAAGGAATTTCATTTCCACTATGAAAATGAATTTGGTGGTGTGCGCGATATCGACATTCCTTTTG
AGGGAGTTGTCAATAATATCAAACGTCGTTACCATGAGACTAACAGTGATTACACGCGCACCCAGATGCGTCTCTACATG
AATGAGCTGACCTGCGGGACTTGTCACGGCTACCGTCTCAATGACCAGGCCTTGTCTGTCCGTGTGGGTGGTGAGCAAGG
GCTACATATCGGTGAAATCTCAGACCTGTCTATCGCAGACCACTTGGAATTAGTGAGCCAGCTGACCTTGTCAGAAAATG
AAGCCATCATTGCTCGGCCCATTCTCAAGGAAATCAAGGATCGCTTGACCTTCCTCAATAACGTGGGACTCAACTATCTG
ACCCTATCACGCTCGGCAGGAACTCTTTCAGGTGGTGAGAGCCAGCGTATTCGCTTGGCAACCCAGATTGGTTCCAATCT
ATCAGGTGTCCTCTATATTCTAGACGAGCCGTCGATTGGTCTCCACCAGAGGGATAATGACCGCCTGATTGCCAGTCTGA
AAAAGATGCGCGATTTGGGCAATACTCTCATCGTGGTGGAACATGATGAAGATACCATGCGAGAGGCAGATTATCTGATT
GACGTCGGTCCTGGTGCGGGAGCCTTTGGTGGAGAGATCGTCGCTGCAGGCACGCCCAAACAGGTGGCTCGCAACAGCAA
GTCTATCACAGGCCAGTACTTGTCAGGAAAACGTGCCATTCCAGTACCAGCAGAGCGCCGTGCTGGGAATGGTCGCTTTA
TCGAAGTGACAGGAGCGCGTGAGAACAACTTGCAAAATATCACTGCTCGTTTCCCATTAGGAAAATTCATCGCAGTGACG
GGGGTATCAGGTTCAGGGAAATCAACCTTAATCAACAGCATCCTCAAAAAAGCCATTGCCCAGAAGCTCAACCGTAATTC
AGACAAACCTGGTAAGTTTAAGACTATTACAGGTATTGAGCATGTAGACCGCTTGATTGACATTGACCAGAGCCCTATCG
GACGGACGCCGAGGTCTAACCCAGCTACTTATACGGGAGTTTTTGACGATATACGTGACCTCTTTGCCCAGACAAATGAA
GCTAAGATACGAGGCTACAAGAAGGGCCGTTTCAGTTTCAACGTCAAGGGTGGTCGTTGTGAAGCCTGCTCAGGTGACGG
GATTATCAAGATCGAGATGCACTTCTTACCAGATGTTTATGTGGCTTGTGAAGTCTGCCACGGAACTCGCTACAACAGTG
AAACTCTAGAAGTCCACTACAAGGAAAAAAATATTTCGCAGGTTTTGGACATGACCGTCAACGATGCGGTGGAATTCTTC
CAACACATTCCCAAGATTCAACGCAAACTTCAGACCATCAAGGATGTGGGGCTGGGCTATGTAACGTTAGGGCAACCAGC
TACGACCCTTTCTGGGGGAGAAGCCCAGCGTATGAAGCTGGCTAGTGAACTCCACAAACGCTCGACAGGAAAATCCTTCT
ACATTCTGGATGAGCCAACGACAGGCCTTCATACAGAGGACATTGCTCGCTTGCTTAAAGTCTTGGCTCGCTTTGTTGAC
GATGGCAATACCGTCCTCGTCATCGAGCACAATCTAGACGTCATCAAGACAGCAGACCATATTATCGACTTGGGACCTGA
GGGCGGTGTTGGTGGTGGAACCATCATCGCAACAGGAACTCCAGAAGAAGTAGCGGCTAATGAAGCCAGCTACACAGGAC
ACTATTTGAAAGGAAAGTTACATCATGAATAA

Domains

Predicted by InterProScan.

UvrA DNA-binding domain (UvrA_DNA-bind)

(288-396)

ABC transporter (ABC_tran)

(624-860)

UvrA interaction domain (UvrA_inter)

(132-238)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

98.197

100

0.982
  uvrA Streptococcus pneumoniae TIGR4

98.197

100

0.982
  uvrA Streptococcus pneumoniae D39

98.197

100

0.982

Multiple sequence alignment